Henrik Nyhus Kløverpris

Henrik Nyhus Kløverpris

Associate Professor

ORCID: 0000-0002-2165-3313

Publication year:
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1 - 25 out of 61Page size: 25
  1. 2023
  2. Published

    Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype

    Vieira, V., Lim, N., Singh, A., Leitman, E., Dsouza, R., Adland, E., Muenchhoff, M., Roider, J., Lopez, M. M., Carabelli, J., Giandhari, J., Groll, A., Jooste, P., Prado, J. G., Thobakgale, C., Dong, K., Kiepiela, P., Prendergast, A. J., Tudor-Williams, G., Frater, J. & 6 others, Walker, B. D., Ndung'U, T., Ramsuran, V., Leslie, A., Kløverpris, Henrik Nyhus & Goulder, P., 2023, In: JCI insight. 8, 3, e156049.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2022

  4. A simple, robust flow cytometry-based whole blood assay for investigating sex differential interferon alpha production by plasmacytoid dendritic cells

    Sampson, O., Lim, N., White, J., Vieira, V., Kløverpris, Henrik Nyhus, Adland, E., Conlon, C., Skelly, D., Jones, L., Stafford, L., Jamsen, A., Barnes, E., Dunachie, S., Frater, J., Klenerman, P., Altfeld, M. & Goulder, P., 2022, In: Journal of Immunological Methods. 504, 113263.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity

    Riou, C., Keeton, R., Moyo-Gwete, T., Hermanus, T., Kgagudi, P., Baguma, R., Valley-Omar, Z., Smith, M., Tegally, H., Doolabh, D., Iranzadeh, A., Tyers, L., Mutavhatsindi, H., Tincho, M. B., Benede, N., Marais, G., Chinhoyi, L. R., Mennen, M., Skelem, S., du Bruyn, E. & 31 others, Stek, C., de Oliveira, T., Williamson, C., Moore, P. L., Wilkinson, R. J., Ntusi, N. A. B., Burgers, W. A., Abrahams, F., Ayres, F., du Toit, E., Goliath, R. T., Hanekom, W., Hardie, D., Hsiao, N. Y., Kløverpris, Henrik Nyhus, Korsman, S., Lakay, F., Lambson, B., Leslie, A., Makhado, Z., Maseko, M., Mhlanga, D., Naidoo, M., Ndhlovu, Z., Ngomti, A., Oosthuysen, B., Ruzive, S., Sigal, A., Smith, T., van der Westhuizen, D. & South African Cellular Immunity Network, S. A. C. I. N., 2022, In: Science Translational Medicine. 14, 631, eabj6824.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway

    Krause, R., Snyman, J., Shi-Hsia, H., Muema, D., Karim, F., Ganga, Y., Ngoepe, A., Zungu, Y., Gazy, I., Bernstein, M., Khan, K., Mazibuko, M., Mthabela, N., Ramjit, D., Limbo, O., Jardine, J., Sok, D., Wilson, I. A., Hanekom, W., Sigal, A. & 4 others, Kløverpris, Henrik Nyhus, Ndung'u, T., Leslie, A. & COMMIT-KZN Team, C. T., 2022, In: eLife. 11, e79924.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control

    Fardoos, R., Nyquist, S. K., Asowata, O. E., Kazer, S. W., Singh, A., Ngoepe, A., Giandhari, J., Mthabela, N., Ramjit, D., Singh, S., Karim, F., Buus, S., Anderson, F., Porterfield, J. Z., Sibiya, A. L., Bipath, R., Moodley, K., Kuhn, W., Berger, B., Nguyen, S. & 6 others, de Oliveira, T., Ndung’u, T., Goulder, P., Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2022, In: Frontiers in Immunology. 13, 912038.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

    Cele, S., Jackson, L., Khoury, D. S., Khan, K., Moyo-Gwete, T., Tegally, H., San, J. E., Cromer, D., Scheepers, C., Amoako, D. G., Karim, F., Bernstein, M., Lustig, G., Archary, D., Smith, M., Ganga, Y., Jule, Z., Reedoy, K., Hwa, S. H., Giandhari, J. & 32 others, Blackburn, J. M., Gosnell, B. I., Abdool Karim, S. S., Hanekom, W., Davies, M. A., Hsiao, M., Martin, D., Mlisana, K., Wibmer, C. K., Williamson, C., York, D., Harrichandparsad, R., Herbst, K., Jeena, P., Khoza, T., Kløverpris, Henrik Nyhus, Leslie, A., Madansein, R., Magula, N., Manickchund, N., Marakalala, M., Mazibuko, M., Moshabela, M., Mthabela, N., Naidoo, K., Ndhlovu, Z., Ndung’u, T., Ngcobo, N., Nyamande, K., Patel, V., NGS-SA, N. & COMMIT-KZN Team, C. T., 2022, In: Nature. 602, 7898, p. 654-656 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Omicron infection enhances Delta antibody immunity in vaccinated persons

    Khan, K., Karim, F., Cele, S., Reedoy, K., San, J. E., Lustig, G., Tegally, H., Rosenberg, Y., Bernstein, M., Jule, Z., Ganga, Y., Ngcobo, N., Mazibuko, M., Mthabela, N., Mhlane, Z., Mbatha, N., Miya, Y., Giandhari, J., Ramphal, Y., Naidoo, T. & 31 others, Sivro, A., Samsunder, N., Kharsany, A. B. M., Amoako, D., Bhiman, J. N., Manickchund, N., Abdool Karim, Q., Magula, N., Abdool Karim, S. S., Gray, G., Hanekom, W., von Gottberg, A., Harrichandparsad, R., Herbst, K., Jeena, P., Khoza, T., Kløverpris, Henrik Nyhus, Leslie, A., Madansein, R., Marakalala, M., Moshabela, M., Naidoo, K., Ndhlovu, Z., Ndung’u, T., Nyamande, K., Patel, V., Smit, T., Steyn, A., Wong, E., Milo, R. & COMMIT-KZN Team, C. T., 2022, In: Nature. 607, 7918, p. 356-359 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Similar Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 in Individuals Living Without and with Human Immunodeficiency Virus on Antiretroviral Therapy during the First South African Infection Wave

    Snyman, J., Hwa, S. H., Krause, R., Muema, D., Reddy, T., Ganga, Y., Karim, F., Leslie, A., Sigal, A., Ndung'U, T., Archary, M., Dullabh, K. J., Goulder, P., Harling, G., Harrichandparsad, R., Herbst, K., Jeena, P., Khoza, T., Klein, N., Kloverpris, H. & 13 others, Madansein, R., Marakalala, M., Mazibuko, M., Moshabela, M., Mthabela, N., Naidoo, K., Ndhlovu, Z., Nyamande, K., Padayatchi, N., Patel, V., Smit, T., Steyn, A. & Wong, E., 2022, In: Clinical Infectious Diseases. 75, 1, p. E249-E256

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation

    Kummerlowe, C., Mwakamui, S., Hughes, T. K., Mulugeta, N., Mudenda, V., Besa, E., Zyambo, K., Shay, J. E. S., Fleming, I., Vukovic, M., Doran, B. A., Aicher, T. P., Wadsworth, M. H., Bramante, J. T., Uchida, A. M., Fardoos, R., Asowata, O. E., Herbert, N., Yilmaz, Ö. H., Kløverpris, H. N. & 6 others, Garber, J. J., Ordovas-Montañes, J., Gartner, Z. J., Wallach, T., Shalek, A. K. & Kelly, P., 2022, In: Science Translational Medicine. 14, 660, eabi8633.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2021
  13. Published

    Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma

    Cele, S., Network for Genomic Surveillance in South Africa, N. F. G. S. I. S. A. & COMMIT-KZN Team, C. T., 2021, In: Nature. 593, 7857, p. 142-146 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

    Fardoos, R., Asowata, O. E., Herbert, N., Nyquist, S. K., Zungu, Y., Singh, A., Ngoepe, A., Mbano, I. M., Mthabela, N., Ramjit, D., Karim, F., Kuhn, W., Madela, F. G., Manzini, V. T., Anderson, F., Berger, B., Pers, Tune H, Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 16, e148920.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    HIV status alters disease severity and immune cell responses in beta variant sars-COV-2 infection wave

    COMMIT-KZN Team, C. T., 2021, In: eLife. 10, e67397.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Irreversible depletion of intestinal CD4+ T cells is associated with T cell activation during chronic HIV infection

    Asowata, O. E., Singh, A., Ngoepe, A., Herbert, N., Fardoos, R., Reddy, K., Zungu, Y., Nene, F., Mthabela, N., Ramjit, D., Karim, F., Govender, K., Ndung’u, T., Zachary Porterfield, J., Adamson, J. H., Madela, F. G., Manzini, V. T., Anderson, F., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 22, e146162.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy

    Lustig, G., Cele, S., Karim, F., Derache, A., Ngoepe, A., Khan, K., Gosnell, B. I., Moosa, M. Y. S., Ntshuba, N., Marais, S., Jeena, P. M., Govender, K., Adamson, J., Kløverpris, Henrik Nyhus, Gupta, R. K., Harrichandparsad, R., Patel, V. B. & Sigal, A., 2021, In: PLOS Pathogens. 17, 9, 21 p., e1009871.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung

    Ogongo, P., Tezera, L. B., Ardain, A., Nhamoyebonde, S., Ramsuran, D., Singh, A., Ng’oepe, A., Karim, F., Naidoo, T., Khan, K., Dullabh, K. J., Fehlings, M., Lee, B. H., Nardin, A., Lindestam Arlehamn, C. S., Sette, A., Behar, S. M., Steyn, A. J. C., Madansein, R., Kløverpris, H. N. & 2 others, Elkington, P. T. & Leslie, A., 2021, In: Journal of Clinical Investigation. 131, 10, e142014.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2020

  20. Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life

    Attaf, M., Roider, J., Malik, A., Rius Rafael, C., Dolton, G., Predergast, A. J., Leslie, A., Ndung'u, T., Kløverpris, Henrik Nyhus, Sewell, A. K. & Goulder, P. J., 2020, In: Frontiers in Immunology. 11, 1587.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection

    Muenchhoff, M., Chung, A. W., Roider, J., Dugast, A. S., Richardson, S., Kløverpris, Henrik Nyhus, Leslie, A., Ndung’u, T., Moore, P., Alter, G. & Gouldera, P. J. R., 2020, In: mSphere. 5, 6, p. 1-16 e00880-20.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy

    Singh, A., Kazer, S. W., Roider, J., Krista, K. C., Millar, J., Asowata, O. E., Ngoepe, A., Ramsuran, D., Fardoos, R., Ardain, A., Muenchhoff, M., Kuhn, W., Karim, F., Ndung'u, T., Shalek, A. K., Goulder, P., Leslie, A. & Kløverpris, Henrik Nyhus, 2020, In: Cell Reports. 32, 11, 108153.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection

    Magnoumba, M., Singh, A., Ogongo, P., Roider, J., Asowata, O., Fehlings, M., Karim, F., Ndung'u, T., Anderson, F., Leslie, A. & Kløverpris, Henrik Nyhus, 2020, In: Frontiers in Immunology. 11, 579743.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2019
  25. Published

    Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children

    Muenchhoff, M., Adland, E., Roider, J., Kløverpris, Henrik Nyhus, Leslie, A., Boehm, S., Keppler, O. T., Ndung'u, T. & Goulder, P. J. R., 2019, In: The Journal of Infectious Diseases. 219, 9, p. 1407-1417 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

    Ardain, A., Domingo-Gonzalez, R., Das, S., Kazer, S. W., Howard, N. C., Singh, A., Ahmed, M., Nhamoyebonde, S., Rangel-Moreno, J., Ogongo, P., Lu, L., Ramsuran, D., de la Luz Garcia-Hernandez, M., K. Ulland, T., Darby, M., Park, E., Karim, F., Melocchi, L., Madansein, R., Dullabh, K. J. & 16 others, Dunlap, M., Marin-Agudelo, N., Ebihara, T., Ndung’u, T., Kaushal, D., Pym, A. S., Kolls, J. K., Steyn, A., Zúñiga, J., Horsnell, W., Yokoyama, W. M., Shalek, A. K., Kløverpris, Henrik Nyhus, Colonna, M., Leslie, A. & Khader, S. A., 2019, In: Nature. 570, 7762, p. 528-532

    Research output: Contribution to journal › Letter › Research › peer-review

  27. Published

    Increased regulatory T-cell activity and enhanced T-cell homeostatic signaling in slow progressing HIV-infected children

    Roider, J., Ngoepe, A., Muenchhoff, M., Adland, E., Groll, A., Ndung'u, T., Kløverpris, Henrik Nyhus, Goulder, P. & Leslie, A., 2019, In: Frontiers in Immunology. 10, FEB, 12 p., 213.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Plasma IL-5 but not CXCL13 correlates with neutralization breadth in HIV-infected children

    Roider, J., Zachary Porterfield, J., Ogongo, P., Muenchhoff, M., Adland, E., Groll, A., Morris, L., Moore, P. L., Ndung'U, T., Kløverpris, Henrik Nyhus, Goulder, P. J. R. & Leslie, A., 2019, In: Frontiers in Immunology. 10, JUL, 9 p., 1497.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis

    Wong, E. B., Gold, M. C., Meermeier, E. W., Xulu, B. Z., Khuzwayo, S., Sullivan, Z. A., Mahyari, E., Rogers, Z., Kløverpris, H., Sharma, P. K., Worley, A. H., Lalloo, U., Baijnath, P., Ambaram, A., Naidoo, L., Suleman, M., Madansein, R., McLaren, J. E., Ladell, K., Miners, K. L. & 8 others, Price, D. A., Behar, S. M., Nielsen, M., Kasprowicz, V. O., Leslie, A., Bishai, W. R., Ndung’u, T. & Lewinsohn, D. M., 2019, In: Communications Biology. 2, 1, 13 p., 203.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Type 3 ILCs in lung disease

    Ardain, A., Porterfield, J. Z., Kløverpris, Henrik Nyhus & Leslie, A., 2019, In: Frontiers in Immunology. 10, JAN, 92.

    Research output: Contribution to journal › Review › Research › peer-review

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ID: 43835678