Henrik Nyhus Kløverpris

Henrik Nyhus Kløverpris

Associate Professor


  1. 2016
  2. Published

    Human T cell responses to Japanese encephalitis virus in health and disease

    Turtle, L., Bali, T., Buxton, G., Chib, S., Chan, S., Soni, M., Hussain, M., Isenman, H., Fadnis, P., Venkataswamy, M. M., Satishkumar, V., Lewthwaite, P., Kurioka, A., Krishna, S., Shankar, M. V., Ahmed, R., Begum, A., Ravi, V., Desai, A., Yoksan, S. & 7 others, Fernandez, S., Willberg, C. B., Kløverpris, Henrik Nyhus, Conlon, C., Klenerman, P., Satchidanandam, V. & Solomon, T., 2016, In: Journal of Experimental Medicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells

    Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells

    Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Role of HLA adaptation in HIV evolution

    Kløverpris, Henrik Nyhus, Leslie, A. & Goulder, P., 2016, In: Frontiers in Immunology. 6, 15 p., 665.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-Infection in the Absence of Viral Suppression

    Kløverpris, H. N., Kazer, S. W., Mjösberg, J., Mabuka, J. M., Wellmann, A., Ndhlovu, Z., Yadon, M. C., Nhamoyebonde, S., Muenchhoff, M., Simoni, Y., Andersson, F., Kuhn, W., Garrett, N., Burgers, W. A., Kamya, P., Pretorius, K., Dong, K., Moodley, A., Newell, E. W., Kasprowicz, V. & 6 others, Abdool Karim, S. S., Goulder, P., Shalek, A. K., Walker, B. D., Ndung'u, T. & Leslie, A., 16 Feb 2016, In: Immunity. 44, 2, p. 391-405 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

    Muenchhoff, M., Adland, E., Karimanzira, O., Crowther, C., Pace, M., Csala, A., Leitman, E., Moonsamy, A., McGregor, C., Hurst, J., Groll, A., Mori, M., Sinmyee, S., Thobakgale, C., Tudor-Williams, G., Prendergast, A. J., Kloverpris, H., Roider, J., Leslie, A., Shingadia, D. & 10 others, Brits, T., Daniels, S., Frater, J., Willberg, C. B., Walker, B. D., Ndung'u, T., Jooste, P., Moore, P. L., Morris, L. & Goulder, P., 28 Sep 2016, In: Science Translational Medicine. 8, 358, 15 p., 358ra125.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2017
  9. Published

    Immunodominant cytomegalovirus-specific CD8+ T-cell responses in sub-Saharan African populations

    Malik, A., Adland, E., Laker, L., Kløverpris, Henrik Nyhus, Fardoos, R., Roider, J., Severinsen, M. C., Chen, F., Riddell, L., Edwards, A., Buus, Søren, Jooste, P., Matthews, P. C. & Goulder, P. J. R., 2017, In: PLOS ONE. 12, 12, 15 p., e0189612.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

    Simoni, Y., Fehlings, M., Kloverpris, H. N., McGovern, N., Koo, S-L., Loh, C. Y., Lim, S., Kurioka, A., Fergusson, J. R., Tang, C-L., Kam, M. H., Dennis, K., Lim, T. K. H., Fui, A. C. Y., Hoong, C. W., Chan, J. K. Y., de Lafaille, M. C., Narayanan, S., Baig, S., Shabeer, M. & 11 others, Toh, S. E. S., Tan, H. K. K., Anicete, R., Tan, E., Takano, A., Klenerman, P., Leslie, A., Tan, D. S. W., Tan, I. B., Ginhoux, F. & Newell, E. W., 17 Jan 2017, In: Immunity. 46, 1, p. 148-161

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2018
  12. Published

    High-frequency, functional HIV-specific T-follicular helper and regulatory cells are present within germinal centers in children but not adults

    Roider, J., Maehara, T., Ngoepe, A., Ramsuran, D., Muenchhoff, M., Adland, E., Aicher, T., Kazer, S. W., Jooste, P., Karim, F., Kuhn, W., Shalek, A. K., Ndung'u, T., Morris, L., Moore, P. L., Pillai, S., Kløverpris, Henrik Nyhus, Goulder, P. & Leslie, A., 2018, In: Frontiers in Immunology. 9, 14 p., 1975.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells

    Attaf, M., Malik, A., Severinsen, M. C., Roider, J., Ogongo, P., Buus, Søren, Ndung'u, T., Leslie, A., Kløverpris, Henrik Nyhus, Matthews, P. C., Sewell, A. K. & Goulder, P., 2018, In: Frontiers in Immunology. 9, 2539.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy

    Muenchhoff, M., Healy, M., Singh, R., Roider, J., Groll, A., Kindra, C., Sibaya, T., Moonsamy, A., McGregor, C., Phan, M. Q., Palma, A., Kløverpris, Henrik Nyhus, Leslie, A., Bobat, R., Larussa, P., Ndung'U, T., Goulder, P., Sobieszczyk, M. E. & Archary, M., Jan 2018, In: AIDS Research and Human Retroviruses. 34, 1, p. 46-55 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2019
  16. Published

    Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children

    Muenchhoff, M., Adland, E., Roider, J., Kløverpris, Henrik Nyhus, Leslie, A., Boehm, S., Keppler, O. T., Ndung'u, T. & Goulder, P. J. R., 2019, In: The Journal of Infectious Diseases. 219, 9, p. 1407-1417 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

    Ardain, A., Domingo-Gonzalez, R., Das, S., Kazer, S. W., Howard, N. C., Singh, A., Ahmed, M., Nhamoyebonde, S., Rangel-Moreno, J., Ogongo, P., Lu, L., Ramsuran, D., de la Luz Garcia-Hernandez, M., K. Ulland, T., Darby, M., Park, E., Karim, F., Melocchi, L., Madansein, R., Dullabh, K. J. & 16 others, Dunlap, M., Marin-Agudelo, N., Ebihara, T., Ndung’u, T., Kaushal, D., Pym, A. S., Kolls, J. K., Steyn, A., Zúñiga, J., Horsnell, W., Yokoyama, W. M., Shalek, A. K., Kløverpris, Henrik Nyhus, Colonna, M., Leslie, A. & Khader, S. A., 2019, In: Nature. 570, 7762, p. 528-532

    Research output: Contribution to journalLetterResearchpeer-review

  18. Published

    Increased regulatory T-cell activity and enhanced T-cell homeostatic signaling in slow progressing HIV-infected children

    Roider, J., Ngoepe, A., Muenchhoff, M., Adland, E., Groll, A., Ndung'u, T., Kløverpris, Henrik Nyhus, Goulder, P. & Leslie, A., 2019, In: Frontiers in Immunology. 10, FEB, 12 p., 213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Plasma IL-5 but not CXCL13 correlates with neutralization breadth in HIV-infected children

    Roider, J., Zachary Porterfield, J., Ogongo, P., Muenchhoff, M., Adland, E., Groll, A., Morris, L., Moore, P. L., Ndung'U, T., Kløverpris, Henrik Nyhus, Goulder, P. J. R. & Leslie, A., 2019, In: Frontiers in Immunology. 10, JUL, 9 p., 1497.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis

    Wong, E. B., Gold, M. C., Meermeier, E. W., Xulu, B. Z., Khuzwayo, S., Sullivan, Z. A., Mahyari, E., Rogers, Z., Kløverpris, H., Sharma, P. K., Worley, A. H., Lalloo, U., Baijnath, P., Ambaram, A., Naidoo, L., Suleman, M., Madansein, R., McLaren, J. E., Ladell, K., Miners, K. L. & 8 others, Price, D. A., Behar, S. M., Nielsen, M., Kasprowicz, V. O., Leslie, A., Bishai, W. R., Ndung’u, T. & Lewinsohn, D. M., 2019, In: Communications Biology. 2, 1, 13 p., 203.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Type 3 ILCs in lung disease

    Ardain, A., Porterfield, J. Z., Kløverpris, Henrik Nyhus & Leslie, A., 2019, In: Frontiers in Immunology. 10, JAN, 92.

    Research output: Contribution to journalReviewResearchpeer-review

  22. 2020
  23. Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life

    Attaf, M., Roider, J., Malik, A., Rius Rafael, C., Dolton, G., Predergast, A. J., Leslie, A., Ndung'u, T., Kløverpris, Henrik Nyhus, Sewell, A. K. & Goulder, P. J., 2020, In: Frontiers in Immunology. 11, 1587.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection

    Muenchhoff, M., Chung, A. W., Roider, J., Dugast, A. S., Richardson, S., Kløverpris, Henrik Nyhus, Leslie, A., Ndung’u, T., Moore, P., Alter, G. & Gouldera, P. J. R., 2020, In: mSphere. 5, 6, p. 1-16 e00880-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy

    Singh, A., Kazer, S. W., Roider, J., Krista, K. C., Millar, J., Asowata, O. E., Ngoepe, A., Ramsuran, D., Fardoos, R., Ardain, A., Muenchhoff, M., Kuhn, W., Karim, F., Ndung'u, T., Shalek, A. K., Goulder, P., Leslie, A. & Kløverpris, Henrik Nyhus, 2020, In: Cell Reports. 32, 11, 108153.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection

    Magnoumba, M., Singh, A., Ogongo, P., Roider, J., Asowata, O., Fehlings, M., Karim, F., Ndung'u, T., Anderson, F., Leslie, A. & Kløverpris, Henrik Nyhus, 2020, In: Frontiers in Immunology. 11, 579743.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2021
  28. Published

    Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma

    Cele, S., Network for Genomic Surveillance in South Africa, N. F. G. S. I. S. A. & COMMIT-KZN Team, C. T., 2021, In: Nature. 593, 7857, p. 142-146 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

    Fardoos, R., Asowata, O. E., Herbert, N., Nyquist, S. K., Zungu, Y., Singh, A., Ngoepe, A., Mbano, I. M., Mthabela, N., Ramjit, D., Karim, F., Kuhn, W., Madela, F. G., Manzini, V. T., Anderson, F., Berger, B., Pers, Tune H, Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 16, e148920.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    HIV status alters disease severity and immune cell responses in beta variant sars-COV-2 infection wave

    COMMIT-KZN Team, C. T., 2021, In: eLife. 10, e67397.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Irreversible depletion of intestinal CD4+ T cells is associated with T cell activation during chronic HIV infection

    Asowata, O. E., Singh, A., Ngoepe, A., Herbert, N., Fardoos, R., Reddy, K., Zungu, Y., Nene, F., Mthabela, N., Ramjit, D., Karim, F., Govender, K., Ndung’u, T., Zachary Porterfield, J., Adamson, J. H., Madela, F. G., Manzini, V. T., Anderson, F., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 22, e146162.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 43835678