Jannick Prentø

Jannick Prentø

Associate Professor

Member of:


    1. 2023
    2. Published

      Identification of novel neutralizing determinants for protection against HCV

      Alzua, G. P., Pihl, A. F., Offersgaard, Anna Falden, Velázquez-Moctezuma, R., Duarte Hernandez, Carlos Rene, Augestad, Elias Honerød, Fahnøe, Ulrik, Mathiesen, C. K., Krarup, H., Law, M., Prentø, Jannick, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Hepatology. 73, 3, p. 982-996

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice

      Alzua, G. P., Pihl, A. F., Offersgaard, Anna Falden, Duarte Hernandez, Carlos Rene, Duan, Z., Feng, S., Fahnøe, Ulrik, Sølund, C., Weis, Nina, Law, M., Prentø, Jannick, Christensen, Jan Pravsgaard, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Gut. 72, 3, p. 560-572

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. 2022
    5. Published

      Inactivated whole hepatitis C virus vaccine employing a licensed adjuvant elicits cross-genotype neutralizing antibodies in mice

      Pihl, A. F., Feng, S., Offersgaard, Anna Falden, Alzua, G. P., Augestad, Elias Honerød, Mathiesen, C. K., Jensen, T. B., Krarup, H., Law, M., Prentø, Jannick, Christensen, Jan Pravsgaard, Bukh, Jens & Gottwein, Judith Margarete, 2022, In: Journal of Hepatology. 76, 5, p. 1051-1061

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Novel HCV Genotype 4d Infectious Systems and Assessment of Direct-Acting Antivirals and Antibody Neutralization

      Pham, Long, Velázquez-Moctezuma, R., Fahnøe, Ulrik, Collignon, Laura Maria F, Bajpai, P., Sølund, C., Weis, Nina, Holmbeck, Kenn, Prentø, Jannick & Bukh, Jens, 2022, In: Viruses. 14, 11, 2527.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers

      Prentø, Jannick, Janitzek, C. M., Velázquez-Moctezuma, R., Sørensen, Andreas Holst Holmegaard, Jørgensen, T., Clemmensen, S., Soroka, V., Thrane, Susan, Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Bukh, Jens & Sander, Adam F. , 2022, In: npj Vaccines. 7, 148.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. 2021
    9. Published

      In vitro adaptation and characterization of attenuated hypervariable region 1 swap chimeras of hepatitis C virus

      Olesen, C. H., Augestad, Elias Honerød, Troise, F., Bukh, Jens & Prentø, Jannick, 2021, In: PLOS Pathogens. 17, July, 29 p., e1009720.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Antigenic and immunogenic evaluation of permutations of soluble hepatitis C virus envelope protein E2 and E1 antigens

      Prentø, Jannick, Janitzek, C. M., Velázquez-Moctezuma, R., Goksøyr, L., Olsen, Rebecca Wendelboe, Fanalista, Margherita, Augestad, Elias Honerød, Thrane, Susan, Pihl, A. F., Gottwein, Judith Margarete, Sander, Adam F. & Bukh, Jens, 2021, In: PLoS ONE. 16, e0255336.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins

      Chen, F., Tzarum, N., Lin, X., Giang, E., Velázquez-Moctezuma, R., Augestad, Elias Honerød, Nagy, K., He, L., Hernandez, M., Fouch, M. E., Grinyó, A., Chavez, D., Doranz, B. J., Prentø, Jannick, Stanfield, R. L., Lanford, R., Bukh, Jens, Wilson, I. A., Zhu, J. & Law, M., 2021, In: Immunity. 54, 4, p. 781-796.e4

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Hepatitis C virus envelope protein dynamics and the link to hypervariable region 1

      Augestad, Elias Honerød, Bukh, Jens & Prentø, Jannick, 2021, In: Current Opinion in Virology. 50, p. 69-75 7 p.

      Research output: Contribution to journalReviewResearchpeer-review

    13. Published

      Mechanisms of hepatitis C virus escape from vaccine-relevant neutralizing antibodies

      Velázquez-Moctezuma, R., Augestad, Elias Honerød, Castelli, M., Olesen, C. H., Clementi, N., Clementi, M., Mancini, N. & Prentø, Jannick, 2021, In: Vaccines. 9, 3, 291.

      Research output: Contribution to journalReviewResearchpeer-review

    14. 2020
    15. Published

      An alternate conformation of HCV E2 neutralizing face as an additional vaccine target

      Tzarum, N., Giang, E., Kadam, R. U., Chen, F., Nagy, K., Augestad, E. H., Velázquez-Moctezuma, R., Keck, Z. Y., Hua, Y., Stanfield, R. L., Dreux, M., Prentø, Jannick, Foung, S. K. H., Bukh, Jens, Wilson, I. A. & Law, M., 2020, In: Science Advances. 6, 30, abb5642.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Global and local envelope protein dynamics of hepatitis C virus determine broad antibody sensitivity

      Augestad, E. H., Castelli, M., Clementi, N., Ströh, L. J., Krey, T., Burioni, R., Mancini, N., Bukh, Jens & Prentø, Jannick, 2020, In: Science Advances. 6, 35, 13 p., eabb5938.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Specific antibodies induced by immunization with hepatitis B virus-like particles carrying hepatitis C virus envelope glycoprotein 2 epitopes show differential neutralization efficiency

      Czarnota, A., Offersgaard, A., Pihl, A. F., Prentø, Jannick, Bukh, Jens, Gottwein, Judith Margarete, Bieńkowska-Szewczyk, K. & Grzyb, K., 2020, In: Vaccines. 8, 2, 19 p., 294.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. 2019
    19. Published

      Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis c virus infections uncover molecular determinants for E2 targeting and vaccine design

      Keck, Z. Y., Pierce, B. G., Lau, P., Lu, J., Wang, Y., Underwood, A., Bull, R. A., Prentø, Jannick, Velázquez-Moctezuma, R., Walker, Melanie Rose, Luciani, F., Guest, J. D., Fauvelle, C., Baumert, T. F., Bukh, Jens, Lloyd, A. R. & Foung, S. K. H., 2019, In: P L o S Pathogens. 15, 5, 28 p., e1007772.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies

      Tzarum, N., Giang, E., Kong, L., He, L., Prentø, Jannick, Augestad, E., Hua, Y., Castillo, S., Lauer, G. M., Bukh, Jens, Zhu, J., Wilson, I. A. & Law, M., 2019, In: Science Advances. 5, 1, 12 p., eaav1882.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Hepatitis C Virus–Escape Studies for Human Monoclonal Antibody AR4A Reveal Isolate-Specific Resistance and a High Barrier to Resistance

      Velázquez-moctezuma, R., Galli, Andrea, Law, M., Bukh, Jens & Prentø, Jannick, 2019, In: The Journal of Infectious Diseases. 219, 1, p. 68-79

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Hepatitis C virus escape studies of human antibody AR3a reveal a high barrier to resistance and novel insights on viral antibody evasion mechanisms

      Velázquez-Moctezuma, R., Galli, Andrea, Law, M., Bukh, Jens & Prentø, Jannick, 2019, In: Journal of Virology. 93, 4, 27 p., e0190918.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Hypervariable region 1 and N-linked glycans of hepatitis C regulate virion neutralization by modulating envelope conformations

      Prentø, Jannick, Velázquez-Moctezuma, R., Augestad, E. H., Galli, Andrea, Wang, R., Law, M., Alter, H. & Bukh, Jens, 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 20, p. 10039-10047 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      In vitro neutralization assay using cultured hepatitis C virus

      Prentø, Jannick & Bukh, Jens, 2019, Hepatitis C Virus Protocols. Humana Press, p. 433-439 7 p. (Methods in Molecular Biology, Vol. 1911).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    25. 2018
    26. Published

      Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry

      Riva, L., Song, O., Prentø, Jannick, Helle, F., L'homme, L., Gattolliat, C., Vandeputte, A., Feneant, L., Belouzard, S., Baumert, T. F., Asselah, T., Bukh, Jens, Brodin, P., Cocquerel, L., Rouille, Y. & Dubuisson, J., 1 May 2018, In: Journal of Virology. 92, 10, 19 p., e01982-17.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      High density Huh7.5 cell hollow fiber bioreactor culture for high-yield production of hepatitis C virus and studies of antivirals

      Pihl, A. F., Offersgaard, A. F., Mathiesen, C. K., Prentø, Jannick, Fahnøe, Ulrik, Krarup, H., Bukh, Jens & Gottwein, Judith Margarete, 2018, In: Scientific Reports. 8, 1, 13 p., 17505.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Hypervariable Region 1 in Envelope Protein 2 of Hepatitis C Virus: A Linchpin in Neutralizing Antibody Evasion and Viral Entry

      Prentø, Jannick & Bukh, Jens, 2018, In: Frontiers in Immunology. 9, 11 p., 2146.

      Research output: Contribution to journalReviewResearchpeer-review

    29. 2017
    30. Published

      Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A

      Velazquez-Moctezuma, R., Law, M., Bukh, Jens & Prentø, Jannick, Feb 2017, In: PLOS Pathogens. 13, 2, 29 p., 1006214.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. 2016
    32. Published

      HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice

      Prentø, Jannick, Verhoye, L., Moctezuma, R. V., Buysschaert, C., Farhoudi, A., Wang, R., Alter, H., Meuleman, P. & Bukh, Jens, Dec 2016, In: Gut. 65, 12, p. 1988-1997 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Hypervariable Region 1 Shielding of Hepatitis C Virus Is a Main Contributor to Genotypic Differences in Neutralization Sensitivity

      Prentø, Jannick, Velazquez-Moctezuma, R., Foung, S. K. H., Law, M. & Bukh, Jens, Dec 2016, In: Hepatology. 64, 6, p. 1881-1892 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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