Thomas Litman
Professor
Immunology
Blegdamsvej 3B, 2200 København N
Member of:
Introductory remarks on publicationslist
For reprints, just write me, or download directly, if available.
- 2017
- Published
Repeated monthly epicutaneous challenges with diphenylcyclopropenone result in a clinically reproducible level of contact allergy in de novo sensitized individuals
Mose, K. F., Andersen, F., Skov, Lone, Røpke, M. A., Litman, Thomas, Friedmann, P. S. & Andersen, K. E., Apr 2017, In: British Journal of Dermatology. 176, 4, p. 1095-1097Research output: Contribution to journal › Letter › Research › peer-review
Effects of glucocorticoids on stratum corneum lipids and function in human skin-A detailed lipidomic analysis
Røpke, M. A., Alonso, C., Jung, S., Norsgaard, H., Richter, C., Darvin, M. E., Litman, Thomas, Vogt, A., Lademann, J., Blume-Peytavi, U. & Kottner, J., 2017, In: Journal of Dermatological Science. 88, 3, p. 330-338 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling
Ewald, D. A., Noda, S., Oliva, M., Litman, Thomas, Nakajima, S., Li, X., Xu, H., Workman, C. T., Scheipers, P., Svitacheva, N., Labuda, T., Krueger, J. G., Suárez-Fariñas, M., Kabashima, K. & Guttman-Yassky, E., 2017, In: Journal of Allergy and Clinical Immunology. 139, 2, p. 562-571 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Adrenocortical cancer: A molecularly complex disease where surgery matters
Payabyab, E. C., Balasubramaniam, S., Edgerly, M., Velarde, M., Merino, M. J., Venkatesan, A. M., Leuva, H., Litman, Thomas, Bates, S. E. & Fojo, T., 15 Oct 2016, In: Clinical Cancer Research. 22, 20, p. 4989-5000 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct molecular signatures of mild extrinsic and intrinsic atopic dermatitis
Martel, B. C., Litman, Thomas, Hald, A., Norsgaard, H., Lovato, P., Dyring-Andersen, Beatrice, Skov, Lone, Thestrup-Pedersen, K., Skov, Søren, Skak, K. & Poulsen, Lars K., Jun 2016, In: Experimental Dermatology Online. 25, 6, p. 453-459 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tumor-Preferential Induction of Immune Responses and Epidermal Cell Death in Actinic Keratoses by Ingenol Mebutate
Emmert, S., Haenssle, H. A., Zibert, J. R., Schön, M., Hald, A., Hansen, M. H., Litman, Thomas & Schön, M. P., 2016, In: PLOS ONE. 11, 9, p. e0160096Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways
Ewald, D. A., Malajian, D., Krueger, J. G., Workman, C. T., Wang, T., Tian, S., Litman, Thomas, Guttman-Yassky, E. & Suárez-Fariñas, M., 12 Oct 2015, In: BMC Medical Genomics. 8, p. 60Research output: Contribution to journal › Journal article › Research › peer-review
miR-155, identified as anti-metastatic by global miRNA profiling of a metastasis model, inhibits cancer cell extravasation and colonization in vivo and causes significant signaling alterations
Thomsen, K. G., Terp, M. G., Lund, R. R., Søkilde, R., Elias, D., Bak, M., Litman, Thomas, Beck, H. C., Lyng, M. B. & Ditzel, H. J., 6 Oct 2015, In: OncoTarget. 6, 30, p. 29224-39 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data
Bates, S. E., Eisch, R., Ling, A., Rosing, D., Turner, M., Pittaluga, S., Prince, H. M., Kirschbaum, M. H., Allen, S. L., Zain, J., Geskin, L. J., Joske, D., Popplewell, L., Cowen, E. W., Jaffe, E. S., Nichols, J., Kennedy, S., Steinberg, S. M., Liewehr, D. J., Showe, L. C. & 5 others, , Jul 2015, In: British Journal of Haematology. 170, 1, p. 96-109 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection
Esaki, H., Ewald, D. A., Ungar, B., Rozenblit, M., Zheng, X., Xu, H., Estrada, Y. D., Peng, X., Mitsui, H., Litman, Thomas, Suárez-Fariñas, M., Krueger, J. G. & Guttman-Yassky, E., Jan 2015, In: The Journal of allergy and clinical immunology. 135, 1, p. 153-63 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma
Ralfkiaer, U., Lindahl, L. M., Litman, Thomas, Gjerdrum, Lise Mette Rahbek, Ahler, C. B., Gniadecki, R., Marstrand, T., Fredholm, S., Iversen, L., Wasik, M. A., Bonefeld, Charlotte Menne, Geisler, Carsten, Krejsgaard, T., Glue, C., Røpke, M. A., Woetmann, A., Skov, Lone, Grønbæk, Kirsten & Ødum, Niels, Dec 2014, In: Anticancer Research. 34, 12, p. 7207-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Channels, Carriers, and Pumps: An Introduction to Membrane Transport
Stein, W. D. & Litman, Thomas, 2014, Elsevier. 406 p.Research output: Book/Report › Book › Research › peer-review
Histone deacetylase inhibitor-mediated cell death is distinct from its global effect on chromatin
Luchenko, V. L., Litman, Thomas, Chakraborty, A. R., Heffner, A., Devor, C., Wilkerson, J., Stein, W., Robey, R. W., Bangiolo, L., Levens, D. & Bates, S. E., 2014, In: Molecular Oncology. 8, 8, p. 1379-1392 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of a diagnostic miRNA classifier in cutaneous T-cell lymphomas
Marstrand, T., Ahler, C. B., Ralfkiaer, U., Clemmensen, A., Kopp, K. L., Sibbesen, N. A., Krejsgaard, T., Litman, Thomas, Wasik, M. A., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Gjerdum, L. M. R., Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Woetmann, Anders , Røpke, M. A., Glue, C., Skov, Lone & Ødum, Niels, 2014, In: Leukemia and Lymphoma. 55, 4, p. 957-958 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma
Kopp, K. L., Ralfkiaer, U., Gjerdrum, Lise Mette Rahbek, Helvad, R., Pedersen, I. H., Litman, Thomas, Jønson, L., Hagedorn, P. H., Krejsgaard, T., Gniadecki, R., Bonefeld, Charlotte Menne, Skov, Lone, Geisler, Carsten, Wasik, M. A., Ralfkiaer, E., Ødum, Niels & Woetmann, A., 2013, In: Cell Cycle. 12, 12, p. 1939-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
Global microRNA expression profiling of high-risk ER+ breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG study
Lyng, M. B., Lænkholm, A. V., Søkilde, R., Gravgaard, K. H., Litman, Thomas & Ditzel, H., 2012, In: PloS one. 7, 5, p. e36170Research output: Contribution to journal › Journal article › Research › peer-review
The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer
Gravgaard, K. H., Lyng, M. B., Laenkholm, A., Søkilde, R., Nielsen, B. S., Litman, Thomas & Ditzel, H., 2012, In: Breast Cancer Research and Treatment. 134, 1, p. 207-217 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The rectal cancer microRNAome - microRNA expression in rectal cancer and matched normal mucosa
Gaedcke, J., Grade, M., Camps, J., Søkilde, R., Kaczkowski, B., Schetter, A. J., Difilippantonio, M. J., Harris, C. C., Ghadimi, B. M., Møller, S., Beissbarth, T., Ried, T. & Litman, Thomas, 2012, In: Clinical Cancer Research. 18, 18, p. 4919-4930 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
MicroRNA expression profiles associated with development of drug resistance in Ehrlich ascites tumor cells
Husted, S., Søkilde, R., Rask, L., Cirera, S., Busk, P. K., Eriksen, J. & Litman, Thomas, 5 Dec 2011, In: Molecular Pharmaceutics. 8, 6, p. 2055-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IFN-α primes T- and NK-cells for IL-15-mediated signaling and cytotoxicity
Hansen, M. L., Woetmann, Anders , Krejsgaard, T., Kopp, K. L. M., Søkilde, R., Litman, Thomas, Straten, P. T., Geisler, Carsten, Wasik, M. A., Ødum, Niels & Eriksen, K. W., Sep 2011, In: Molecular Immunology. 48, 15-16, p. 2087-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer
Martens-Uzunova, E. S., Jalava, S. E., Dits, N. F., van Leenders, G. J. L. H., Møller, S., Trapman, J., Bangma, C. H., Litman, Thomas, Visakorpi, T. & Jenster, G., 18 Jul 2011, In: Oncogene. 31, 8, p. 978-991 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crx broadly modulates the pineal transcriptome
Rovsing, L., Clokie, S., Bustos, D. M., Rohde, K., Coon, S. L., Litman, Thomas, Rath, Martin Fredensborg, Møller, Morten & Klein, D. C., 2011, In: Journal of Neurochemistry. 119, 2, p. 262-74 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)
Ralfkiaer, U., Hagedorn, P., Bangsgaard, N., Løvendorf, M. B., Ahler, C. B., Svensson, L., Kopp, K. L., Vennegaard, M. T., Lauenborg, B., Zibert, J. R., Krejsgaard, T., Bonefeld, C. M., Søkilde, R., Gjerdrum, L. M., Labuda, T., Mathiesen, A-M., Grønbaek, K., Wasik, M. A., Sokolowska-Wojdylo, M., Queille-Roussel, C. & 9 others, , 2011, In: Blood. 118, 22, p. 5891-5900 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High expression of miR-21 in tumor stroma correlates with increased cancer cell proliferation in human breast cancer
Rask, L., Balslev, E., Jørgensen, S., Eriksen, J., Flyger, H., Møller, S., Høgdall, Estrid Vilma Solyom, Litman, Thomas & Nielsen, B. S., 2011, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 119, 10, p. 663-673 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How the RNA isolation method can affect microRNA microarray results
Podolska, A., Kaczkowski, B., Litman, Thomas, Fredholm, Merete & Cirera, Susanna, 2011, In: Acta Biochimica Polonica. 58, 4, p. 535-540 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
MicroRNAs and potential target interactions in psoriasis
Zibert, J. R., Løvendorf, M. B., Litman, Thomas, Olsen, Jørgen, Kaczkowski, B. & Skov, Lone, 2010, In: Journal of Dermatological Science. 58, 3, p. 177-185 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
MicroRNA expression analysis by LNA enhanced microarrays
Søkilde, R., Kaczkowski, B., Barken, K. B., Mouritzen, P., Møller, Søren & Litman, Thomas, 1 Oct 2009, MicroRNA Profiling in Cancer: A Bioinformatics Perspective. Pan Stanford Publishing Pte. Ltd., p. 23-46 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Ammonia and urea permeability of mammalian aquaporins
Litman, Thomas, Søgaard, R. & Zeuthen, Thomas, 2009, In: Handbook of Experimental Pharmacology. 190, p. 327-58 31 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative miRNA expression analysis: comparing microarrays with next-generation sequencing
Willenbrock, H., Salomon, J., Søkilde, R., Barken, K. B., Hansen, T. N., Nielsen, Finn Cilius, Møller, Søren & Litman, Thomas, 2009, In: RNA: A publication of the RNA Society. 15, 11, p. 2028-34 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells
Dejligbjerg, M., Grauslund, M., Litman, Thomas, Collins, L., Qian, X., Jeffers, M., Lichenstein, H., Jensen, P. B. & Sehested, M., 12 Sep 2008, In: Molecular Cancer. 7, 70.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter
Özvegy-Laczka, C., Laczkó, R., Hegedűs, C., Litman, Thomas, Várady, G., Goda, K., Hegedűs, T., Dokholyan, N. V., Sorrentino, B. P., Váradi, A. & Sarkadi, B., 2008, In: The Journal of Biological Chemistry. 283, 38, p. 26059-26070 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
PolyHEMA spheroids are an inadequate model for the drug resistance of the intractable solid tumors
Steadman, K., Stein, W. D., Litman, Thomas, Yang, S. X., Abu-Asab, M., Dutcher, S. K. & Bates, S., 2008, In: Cell Cycle. 7, 6, p. 818-829 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line
To, K. K. W., Zhan, Z., Litman, Thomas & Bates, S. E., 2008, In: Molecular and Cellular Biology. 28, 17, p. 5147-5161 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
A database study that identifies genes whose expression correlates, negatively or positively, with 5-year survival of cancer patients
Stein, W. D., Litman, Thomas, Fojo, T. & Bates, S. E., 2007, In: Biochimica et Biophysica Acta - General Subjects. 1770, 6, p. 857-871 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Data on the recurrence of breast tumors fit a model in which dormant cells are subject to slow attrition but can randomly awaken to become malignant
Stein, W. D. & Litman, Thomas, 2006, In: Cell Cycle. 5, 20, p. 2348-53 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues
Fetsch, P. A., Abati, A., Litman, Thomas, Morisaki, K., Honjo, Y., Mittal, K. & Bates, S. E., 2006, In: Cancer Letters. 235, 1, p. 84-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2
Henriksen, U. B., Fog, J. U., Litman, Thomas & Gether, Ulrik, 4 Nov 2005, In: Journal of Biological Chemistry. 280, 44, p. 36926-34 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2
Henriksen, U. B., Gether, Ulrik & Litman, Thomas, 1 Apr 2005, In: Journal of Cell Science. 118, Pt 7, p. 1417-26 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential expression of cell adhesion genes: implications for drug resistance
Stein, W. D., Litman, Thomas, Fojo, T. & Bates, S. E., 1 Mar 2005, In: International journal of cancer. Journal international du cancer. 113, 6, p. 861-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression profiling in chemoresistant variants of three cell lines of different origin
Johnsson, A., Vallon-Christensson, J., Strand, C., Litman, Thomas & Eriksen, J., 2005, In: Anticancer Research. 25, 4, p. 2661-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
A Serial Analysis of Gene Expression (SAGE) Database Analysis of Chemosensitivity: Comparing Solid Tumors with Cell Lines and Comparing Solid Tumors from Different Tissue Origins: comparing solid tumors with cell lines and comparing solid tumors from different tissue origins
Stein, W. D., Litman, Thomas, Fojo, T. & Bates, S. E., 15 Apr 2004, In: Cancer Research. 64, 8, p. 2805-2816 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bioinformatik, undervisningsformer og IT, Hvad mener de studerende?
Vestergaard, B. F. & Litman, Thomas, 2004, In: Plexus. Vol. 36 (1), p. 16-9Research output: Contribution to journal › Journal article › Research
- Published
Molecular cloning of a K+ channel from the malaria parasite Plasmodium falciparum
Ellekvist, P., Ricke, C. H., Litman, Thomas, Salanti, Ali, Colding, H., Zeuthen, Thomas & Klærke, Dan Arne, 2004, In: Biochemical and Biophysical Research Communications. 318, 2, p. 477-84 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Pumping of drugs by P-glycoprotein: a two-step process?
Litman, Thomas, Skovsgaard, T. & Stein, W. D., Dec 2003, In: Journal of Pharmacology and Experimental Therapeutics. 307, 3, p. 846-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pumping of drugs by P-glycoprotein: a two-step process?
Litman, Thomas, Skovsgaard, T. & Stein, W. D., 2003, In: Pharmacol Exp Ther.. 307(3), p. 846-853Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Functional analysis of candidate ABC transporter proteins for sitosterol transport
Albrecht, C., Elliott, J. I., Sardini, A., Litman, Thomas, Stieger, B., Meier, P. J. & Higgins, C. F., 23 Dec 2002, In: BBA General Subjects. 1567, 1-2, p. 133-42 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2
Litman, Thomas, Jensen, U., Hansen, Alastair, Covitz, K., Zhan, Z., Fetsch, P., Abati, A., Hansen, Paul Robert, Horn, T., Skovsgaard, T. & Bates, S. E., 20 Sep 2002, In: BBA General Subjects. 1565, 1, p. 6-16 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells
Poulsen, K. A., Litman, Thomas, Eriksen, J., Mollerup, J. & Lambert, Ian Henry, Jun 2002, In: Amino Acids. 22, 4, p. 333-50 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of BCRP/MXR, MRP1 and MDR1/P-Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells
Stein, U., Lage, H., Jordan, A., Walther, W., Bates, S. E., Litman, Thomas, Hohenberger, P. & Dietel, M., 20 Feb 2002, In: International journal of cancer. Journal international du cancer. 97, 6, p. 751-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle
Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 5 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 3, p. 1683-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 33298538
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212
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Personalized medicine - concepts, technologies, and applications in inflammatory skin diseases
Research output: Contribution to journal › Review › Research › peer-review
Published -
124
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Obtaining estimates for the ages of all the protein-coding genes and most of the ontology-identified noncoding genes of the human genome, assigned to 19 phylostrata
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
121
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HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503
Research output: Contribution to journal › Journal article › Research › peer-review
Published