Neo-antigen specific memory T-cell responses in healthy individuals
Research output: Contribution to journal › Letter › Research › peer-review
The driver mutations in exon 9 of the calreticulin protein have only been identified in patients with myeloid cancers. We recently demonstrated that healthy individuals display strong and frequent T-cell responses towards this mutation. This memory T-cell response is likely evidence of the elimination of mutated cells in healthy individuals.
Original language | English |
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Article number | 1599640 |
Journal | OncoImmunology |
Volume | 8 |
Issue number | 7 |
Number of pages | 2 |
ISSN | 2162-4011 |
DOIs | |
Publication status | Published - 2019 |
- calreticulin, cancer immunoediting, hematological cancer, memory T-cells, Neoantigens
Research areas
Links
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527287/pdf/koni-08-07-1599640.pdf
Final published version
ID: 223256978