Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer
Research output: Contribution to journal › Journal article › Research › peer-review
Adoptive transfer of tumor-infiltrating lymphocytes (TIL) has proven effective in metastatic melanoma and should therefore be explored in other types of cancer. The aim of this study was to examine the feasibility of potentially expanding clinically relevant quantities of tumor-specific T-cell cultures from TIL from patients with head and neck squamous cell carcinoma (HNSCC) using a more rapid expansion procedure compared with previous HNSCC studies.
| Original language | English |
|---|---|
| Journal | Cytotherapy |
| Volume | 13 |
| Issue number | 7 |
| Pages (from-to) | 822-34 |
| Number of pages | 13 |
| ISSN | 1465-3249 |
| DOIs | |
| Publication status | Published - 2011 |
- Adoptive Transfer, Adult, Aged, Antigens, CD3, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Carcinoma, Squamous Cell, Cells, Cultured, Feeder Cells, Female, Head and Neck Neoplasms, Humans, Immunotherapy, Adoptive, Interferon-gamma, Interleukin-2, Lymphocytes, Tumor-Infiltrating, Male, Middle Aged, Receptors, Antigen, T-Cell, T-Lymphocyte Subsets
Research areas
ID: 38028995