Troels Kasper Høyer Scheel

Troels Kasper Høyer Scheel

Associate Professor, Associate Professor - Promotion Programme

Member of:


    1. 2024
    2. Published

      Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice

      Brown, A. J., Won, J. J., Wolfisberg, R., Fahnøe, U., Catanzaro, N., West, A., Moreira, F. R., Nogueira Batista, M., Ferris, M. T., Linnertz, C. L., Leist, S. R., Nguyen, C., De La Cruz, G., Midkiff, B. R., Xia, Y., Evangelista, M. D., Montgomery, S. A., Billerbeck, E., Bukh, J., Scheel, T. K. H. & 2 others, Rice, C. M. & Sheahan, T. P., 2024, In: Hepatology. 79, 1, p. 183-197

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. 2023
    4. Published

      Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease

      Mullari, M., Fossat, Nicolas Julien, Skotte, Niels Henning, Asenjo-Martinez, A., Humphreys, D. T., Bukh, Jens, Kirkeby, Agnete, Scheel, Troels Kasper Høyer & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 20 p., 4348.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Differential activity of nucleotide analogs against tick-borne encephalitis and yellow fever viruses in human cell lines

      Binderup, A., Galli, Andrea, Fossat, Nicolas Julien, Fernandez-Antunez, C., Mikkelsen, L. S., Rivera, Lizandro, Scheel, Troels Kasper Høyer, Fahnøe, Ulrik, Bukh, Jens & Ramirez, S., 2023, In: Virology. 585, p. 179-185 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide

      Sherwood, A. V., Rivera-Rangel, L. R., Ryberg, L. A., Larsen, H. S., Anker, K. M., Costa, R., Vågbø, C. B., Jakljevič, E., Pham, L. V., Fernandez-Antunez, C., Indrisiunaite, G., Podolska-Charlery, A., Grothen, J. E. R., Langvad, N. W., Fossat, N., Offersgaard, A., Al-Chaer, A., Nielsen, L., Kuśnierczyk, A., Sølund, C. & 8 others, Weis, Nina, Gottwein, Judith Margarete, Holmbeck, Kenn, Bottaro, S., Ramirez Almeida, Santseharay, Bukh, Jens, Scheel, Troels Kasper Høyer & Vinther, Jeppe, 2023, In: Nature. 619, p. 811-818

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Identification of the viral and cellular microRNA interactomes during SARS-CoV-2 infection

      Fossat, Nicolas Julien, Lundsgaard, Emma Alberte, Costa, Rui, Rivera, Lizandro, Nielsen, L., Mikkelsen, L. S., Ramirez Almeida, Santseharay, Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Cell Reports. 42, 4, 112282.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Molecular Determinants of Mouse Adaptation of Rat Hepacivirus

      Wolfisberg, R., Holmbeck, Kenn, Billerbeck, E., Thorselius, Caroline Eva, Batista, M. N., Fahnøe, Ulrik, Lundsgaard, Emma Alberte, Kennedy, Matthew James, Nielsen, L., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Journal of Virology. 97, 4, 17 p., e0181222.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. 2022
    10. Published

      Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals

      Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P., Ramirez Almeida, S. & 4 others, Reichl, U., Genzel, Y., Bukh, Jens & Gottwein, Judith Margarete, 6 Jul 2022.

      Research output: Contribution to conferencePosterCommunication

    11. Published

      Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals

      Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Holmbeck, K., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P. & 5 others, Ramirez Almeida, Santseharay, Reichl, U., Genzel, Y., Bukh, J. & Gottwein, Judith Margarete, 6 Jul 2022.

      Research output: Contribution to conferenceConference abstract for conferenceCommunication

    12. Published

      A distinct dexamethasone-dependent gene expression profile in the lungs of COVID-19 patients

      Fahnøe, Ulrik, Ronit, A., Berg, Ronan Martin Griffin, Jørgensen, S. E., Mogensen, T. H., Underwood, Alexander Paul James, Scheel, Troels Kasper Høyer, Bukh, Jens & Plovsing, R. R., 2022, In: The Journal of Infectious Diseases. 226, 12, p. 2137–2141

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Neutralization and receptor use of infectious culture–derived rat hepacivirus as a model for HCV

      Wolfisberg, R., Thorselius, Caroline Eva, Salinas, E., Elrod, E., Trivedi, S., Nielsen, L., Fahnøe, Ulrik, Kapoor, A., Grakoui, A., Rice, C. M., Bukh, Jens, Holmbeck, Kenn & Scheel, Troels Kasper Høyer, 2022, In: Hepatology. 76, 5, p. 1506-1519

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and Replication

      Fahnøe, Ulrik, Pham, Long, Fernandez-Antunez, C., Costa, Rui, Rivera, Lizandro, Galli, Andrea, Feng, S., Mikkelsen, L. S., Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay & Bukh, Jens, 2022, In: Viruses. 14, 2, 172.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. 2021
    16. Published

      Argonaute-CLIP delineates versatile, functional RNAi networks in Aedes aegypti, a major vector of human viruses

      Rozen-Gagnon, K., Gu, M., Luna, J. M., Luo, J., Yi, S., Novack, S., Jacobson, E., Wang, W., Paul, M. R., Scheel, Troels Kasper Høyer, Carroll, T. & Rice, C. M., 2021, In: Cell Host & Microbe. 29, 5, p. 834-848

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 in Vitro

      Gammeltoft, Karen Anbro, Zhou, Y., Duarte Hernandez, C. R., Galli, Andrea, Offersgaard, Anna Falden, Costa, Rui, Pham, Long, Fahnøe, Ulrik, Feng, S., Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2021, In: Antimicrobial Agents and Chemotherapy. 65, 9, e02680-20.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Pathogenesis, miR-122 gene-regulation, and protective immune responses after acute equine hepacivirus infection

      Tomlinson, J. E., Wolfisberg, R., Fahnøe, Ulrik, Patel, R. S., Trivedi, S., Kumar, A., Sharma, H., Nielsen, L., McDonough, S. P., Bukh, Jens, Tennant, B. C., Kapoor, A., Rosenberg, B. R., Rice, C. M., Divers, T. J., Van de Walle, G. R. & Scheel, Troels Kasper Høyer, 2021, In: Hepatology. 74, 3, p. 1148-1163

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Sars-cov-2 production in a scalable high cell density bioreactor

      Offersgaard, Anna Falden, Hernandez, C. R. D., Pihl, A. F., Costa, Rui, Venkatesan, N. P., Lin, X., Pham, Long, Feng, S., Fahnøe, Ulrik, Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Reichl, U., Bukh, Jens, Genzel, Y. & Gottwein, Judith Margarete, 2021, In: Vaccines. 9, 7, 706.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. 2020
    21. Published

      Evolutionary selection of pestivirus variants with altered or no microRNA dependency

      Kokkonos, K. G., Fossat, Nicolas Julien, Nielsen, L., Holm, C., Hepkema, W. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 4 Jun 2020, In: Nucleic Acids Research. 48, 10, p. 5555-5571 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Equine pegiviruses cause persistent infection of bone marrow and are not associated with hepatitis

      Tomlinson, J. E., Wolfisberg, R., Fahnøe, Ulrik, Sharma, H., Renshaw, R. W., Nielsen, L., Nishiuchi, E., Holm, C., Dubovi, E., Rosenberg, B. R., Tennant, B. C., Bukh, Jens, Kapoor, A., Divers, T. J., Rice, C. M., Van de Walle, G. R. & Scheel, Troels Kasper Høyer, 2020, In: P L o S Pathogens. 16, 7, 23 p., e1008677.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. 2019
    24. Published

      Functional Interplay between RNA Viruses and Non-Coding RNA in Mammals

      Damas, N. D., Fossat, Nicolas Julien & Scheel, Troels Kasper Høyer, 14 Jan 2019, In: Non-coding RNA. 5, 1, 7.

      Research output: Contribution to journalReviewResearchpeer-review

    25. Published

      Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells

      Wolfisberg, R., Holmbeck, Kenn, Nielsen, L., Kapoor, A., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2019, In: Journal of Virology. 93, 19, 19 p., e00733-19.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. 2018
    27. Published

      Viral persistence, liver disease, and host response in a hepatitis C–like virus rat model

      Trivedi, S., Murthy, S., Sharma, H., Hartlage, A. S., Kumar, A., Gadi, S. V., Simmonds, P., Chauhan, L. V., Scheel, Troels Kasper Høyer, Billerbeck, E., Burbelo, P. D., Rice, C. M., Lipkin, W. I., Vandegrift, K., Cullen, J. M. & Kapoor, A., 1 Aug 2018, In: Hepatology. 68, 2, p. 435-448 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Efficacy of NS5A Inhibitors Against Hepatitis C Virus Genotypes 1–7 and Escape Variants

      Gottwein, Judith Margarete, Pham, Long, Mikkelsen, L. S., Ghanem, L., Ramirez Almeida, Santseharay, Scheel, Troels Kasper Høyer, Carlsen, T. H. R. & Bukh, Jens, Apr 2018, In: Gastroenterology. 154, 5, p. 1435-1448 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product

      Divers, T. J., Tennant, B. C., Kumar, A., McDonough, S., Cullen, J., Bhuva, N., Jain, K., Chauhan, L. S., Scheel, Troels Kasper Høyer, Lipkin, W. I., Laverack, M., Trivedi, S., Srinivasa, S., Beard, L., Rice, C. M., Burbelo, P. D., Renshaw, R. W., Dubovi, E. & Kapoor, A., Feb 2018, In: Emerging Infectious Diseases . 24, 2, p. 303-310 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. 2017
    31. Published

      Global mapping of miRNA-target interactions in cattle (Bos taurus)

      Scheel, Troels Kasper Høyer, Moore, M. J., Luna, J. M., Nishiuchi, E., Fak, J., Darnell, R. B. & Rice, C. M., 2017, In: Scientific Reports. 7, 1, 13 p., 8190.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Mouse models of acute and chronic hepacivirus infection

      Billerbeck, E., Wolfisberg, R., Fahnøe, Ulrik, Xiao, J. W., Quirk, C., Luna, J. M., Cullen, J. M., Hartlage, A. S., Chiriboga, L., Ghoshal, K., Lipkin, W. I., Bukh, Jens, Scheel, Troels Kasper Høyer, Kapoor, A. & Rice, C. M., 2017, In: Science. 357, 6347, p. 204-208 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence

      Yu, Y., Scheel, Troels Kasper Høyer, Luna, J. M., Chung, H., Nishiuchi, E., Scull, M. A., Echeverría, N., Ricardo-Lax, I., Kapoor, A., Lipkin, I. W., Divers, T. J., Antczak, D. F., Tennant, B. C. & Rice, C. M., 2017, In: PLOS Pathogens. 13, 10, 21 p., e1006694.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. 2016
    35. Published

      A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration

      Scheel, Troels Kasper Høyer, Luna, J. M., Liniger, M., Nishiuchi, E., Rozen-Gagnon, K., Shlomai, A., Auray, G., Gerber, M., Fak, J., Keller, I., Bruggmann, R., Darnell, R. B., Ruggli, N. & Rice, C. M., 9 Mar 2016, In: Cell Host & Microbe. 19, 3, p. 409-23 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. 2015
    37. Published

      Hepatitis C virus RNA functionally sequesters miR-122

      Luna, J. M., Scheel, Troels Kasper Høyer, Danino, T., Shaw, K. S., Mele, A., Fak, J. J., Nishiuchi, E., Takacs, C. N., Catanese, M. T., de Jong, Y. P., Jacobson, I. M., Rice, C. M. & Darnell, R. B., 12 Mar 2015, In: Cell. 160, 6, p. 1099-110 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Surveying the global virome: identification and characterization of HCV-related animal hepaciviruses

      Scheel, Troels Kasper Høyer, Simmonds, P. & Kapoor, A., Mar 2015, In: Antiviral Research. 115, p. 83-93 11 p.

      Research output: Contribution to journalReviewResearchpeer-review

    39. Published

      Characterization of nonprimate hepacivirus and construction of a functional molecular clone

      Scheel, Troels Kasper Høyer, Kapoor, A., Nishiuchi, E., Brock, K. V., Yu, Y., Andrus, L., Gu, M., Renshaw, R. W., Dubovi, E. J., McDonough, S. P., Van de Walle, G. R., Lipkin, W. I., Divers, T. J., Tennant, B. C. & Rice, C. M., 17 Feb 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 7, p. 2192-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      miRNA-target chimeras reveal miRNA 3'-end pairing as a major determinant of Argonaute target specificity

      Moore, M. J., Scheel, Troels Kasper Høyer, Luna, J. M., Park, C. Y., Fak, J. J., Nishiuchi, E., Rice, C. M. & Darnell, R. B., 2015, In: Nature Communications. 6, 17 p., 8864.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. 2013
    42. Published

      Adapted J6/JFH1-based Hepatitis C virus recombinants with genotype-specific NS4A show similar efficacies against lead protease inhibitors, alpha interferon, and a putative NS4A inhibitor

      Gottwein, Judith Margarete, Jensen, S. B., Serre, S. B. N., Ghanem, L., Scheel, Troels Kasper Høyer, Jensen, T. B., Krarup, H., Uzcategui, N., Mikkelsen, L. S. & Bukh, Jens, Dec 2013, In: Antimicrobial Agents and Chemotherapy. 57, 12, p. 6034-49 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Analysis of hepatitis C virus core/NS5A protein co-localization using novel cell culture systems expressing core-NS2 and NS5A of genotypes 1-7

      Galli, A., Scheel, Troels Kasper Høyer, Prentø, Jannick, Mikkelsen, L. S., Gottwein, Judith Margarete & Bukh, Jens, Oct 2013, In: The Journal of general virology. 94, Pt 10, p. 2221-35 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Understanding the hepatitis C virus life cycle paves the way for highly effective therapies

      Scheel, Troels Kasper Høyer & Rice, C. M., Jul 2013, In: Nature Medicine. 19, 7, p. 837-49 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Identification of a pegivirus (GB virus-like virus) that infects horses

      Kapoor, A., Simmonds, P., Cullen, J. M., Scheel, Troels Kasper Høyer, Medina, J. L., Giannitti, F., Nishiuchi, E., Brock, K. V., Burbelo, P. D., Rice, C. M. & Lipkin, W. I., Jun 2013, In: Journal of Virology. 87, 12, p. 7185-90 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Combination treatment with hepatitis C virus protease and NS5A inhibitors is effective against recombinant genotype 1a, 2a, and 3a viruses

      Gottwein, Judith Margarete, Jensen, S. B., Li, Y., Ghanem, L., Scheel, Troels Kasper Høyer, Serre, S. B. N., Mikkelsen, L. & Bukh, Jens, Mar 2013, In: Antimicrobial Agents and Chemotherapy. 57, 3, p. 1291-303 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Productive homologous and non-homologous recombination of hepatitis C virus in cell culture

      Scheel, Troels Kasper Høyer, Galli, A., Li, Y., Mikkelsen, L. S., Gottwein, Judith Margarete & Bukh, Jens, Mar 2013, In: P L o S Pathogens. 9, 3, p. 1-12 13 p., e1003228.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Characterization of hepatitis C virus recombinants with chimeric E1/E2 envelope proteins and identification of single amino acids in the E2 stem region important for entry

      Carlsen, T. H. R., Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Foung, S. K. H. & Bukh, Jens, 2013, In: Journal of Virology. 87, 3, p. 1385-99 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Identification of rodent homologs of hepatitis C virus and pegiviruses

      Kapoor, A., Simmonds, P., Scheel, Troels Kasper Høyer, Hjelle, B., Cullen, J. M., Burbelo, P. D., Chauhan, L. V., Duraisamy, R., Sanchez Leon, M., Jain, K., Vandegrift, K. J., Calisher, C. H., Rice, C. M. & Lipkin, W. I., 2013, In: mBio. 4, 2, p. e00216-13

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. 2012
    51. Published

      Efficient replication of genotype 3a and 4a hepatitis C virus replicons in human hepatoma cells

      Saeed, M., Scheel, Troels Kasper Høyer, Gottwein, Judith Margarete, Marukian, S., Dustin, L. B., Bukh, Jens & Rice, C. M., Oct 2012, In: Antimicrobial Agents and Chemotherapy. 56, 10, p. 5365-73 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Analysis of functional differences between hepatitis C virus NS5A of genotypes 1-7 in infectious cell culture systems

      Scheel, Troels Kasper Høyer, Prentø, Jannick, Carlsen, T. H. R., Mikkelsen, L. S., Gottwein, Judith Margarete & Bukh, Jens, 2012, In: P L o S Pathogens. 8, 5, p. 1-16 17 p., e1002696.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains

      Li, Y., Ramirez, S., Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Mikkelsen, L., Purcell, R. H. & Bukh, Jens, 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 18, p. E1101-E1110 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. 2011
    55. Published

      Efficient Culture Adaptation of Hepatitis C Virus Recombinants with Genotype-Specific Core-NS2 by Using Previously Identified Mutations

      Scheel, Troels Kasper Høyer, Gottwein, J. M., Carlsen, T. H. R., Li, Y., Jensen, T. B., Spengler, U., Weis, Nina & Bukh, Jens, Mar 2011, In: Journal of Virology. 85, 6, p. 2891-2906 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. Published

      Development and application of hepatitis C reporter viruses with genotype 1 to 7 core-nonstructural protein 2 (NS2) expressing fluorescent proteins or luciferase in modified JFH1 NS5A

      Gottwein, J. M., Jensen, T. B., Mathiesen, C. K., Meuleman, P., Serre, S. B. N., Lademann, J. B., Ghanem, L., Scheel, Troels Kasper Høyer, Leroux-Roels, G. & Bukh, Jens, 2011, In: Journal of Virology. 85, 17, p. 8913-28 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Published

      Differential efficacy of protease inhibitors against HCV genotypes 2a, 3a, 5a, and 6a NS3/4A protease recombinant viruses

      Gottwein, J. M., Scheel, Troels Kasper Høyer, Jensen, T. B., Ghanem, L. & Bukh, Jens, 2011, In: Gastroenterology Today. 141, 3, p. 1067-1079 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Hypervariable region 1 differentially impacts viability of hepatitis C virus strains of genotypes 1 to 6 and impairs virus neutralization

      Prentø, Jannick, Jensen, T. B., Meuleman, P., Serre, S., Scheel, Troels Kasper Høyer, Leroux-Roels, G., Gottwein, J. & Bukh, Jens, 2011, In: Journal of Virology. 85, 5, p. 2224-34 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. Published

      MicroRNA-122 antagonism against hepatitis C virus genotypes 1-6 and reduced efficacy by host RNA insertion or mutations in the HCV 5' UTR

      Li, Y., Gottwein, J., Scheel, Troels Kasper Høyer, Jensen, T. B. & Bukh, Jens, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 12, p. 4991-4996

      Research output: Contribution to journalJournal articleResearchpeer-review

    60. Published

      Recombinant HCV variants with NS5A from genotypes 1-7 have different sensitivities to an NS5A inhibitor but not interferon-a

      Scheel, Troels Kasper Høyer, Gottwein, J. M., Mikkelsen, L. S., Jensen, T. B. & Bukh, Jens, 2011, In: Gastroenterology Today. 140, 3, p. 1032-42 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    61. 2010
    62. Published

      Novel infectious cDNA clones of hepatitis C virus genotype 3a (strain S52) and 4a (strain ED43): genetic analyses and in vivo pathogenesis studies

      Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Callendret, B., Li, Y., Eccleston, H. B., Engle, R. E., Govindarajan, S., Satterfield, W., Purcell, R. H., Walker, C. M. & Bukh, Jens, 2010, In: Journal of Virology. 84, 10, p. 5277-93 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    63. 2009
    64. Published

      DELETION OF HYPERVARIABLE REGION 1 (HVR1) OF E2 FROM HCV GENOTYPES 1-6 HAS DIFFERENTIAL EFFECT ON INFECTIVITY IN VITRO AND CAUSES INCREASED SUSCEPTIBILITY TO NEUTRALIZATION

      Prentø, Jannick, Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Jensen, T. B., Serre, S. & Bukh, Jens, 2009, In: Journal of Hepatology. 50, p. S34-S34

      Research output: Contribution to journalJournal articleResearchpeer-review

    65. Published

      Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: role of CD81 and scavenger receptor class B type I and effect of antiviral drugs

      Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Jensen, T. B., Lademann, J. B., Prentø, Jannick, Knudsen, M. L., Hoegh, A. M. & Bukh, Jens, 2009, In: Hepatology. 49, 2, p. 364-77 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    66. Published

      MONOCISTRONIC HEPATITIS C REPORTER VIRUS RECOMBINANTS OF ALL MAJOR GENOTYPES EXPRESSING ENHANCED GREEN FLUORESCENT PROTEIN TAGGED NS5A PROTEIN

      Gottwein, Judith Margarete, Lademann, J. B., Scheel, Troels Kasper Høyer, Jensen, T. B., Prentø, Jannick & Bukh, Jens, 2009, In: Journal of Hepatology. 50, p. S33-S33

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. 2008
    68. Published

      Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization

      Scheel, Troels Kasper Høyer, Gottwein, Judith Margarete, Jensen, T. B., Prentø, Jannick, Høegh, A. M., Alter, H. J., Eugen-Olsen, J. & Bukh, Jens, 2008, In: Proceedings of the National Academy of Science of the United States of America. 105, 3, p. 997-1002 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    69. Published

      Highly Efficient JFH1-Based Cell-Culture System for Hepatitis C Virus Genotype 5a: Failure of Homologous Neutralizing-Antibody Treatment to Control Infection

      Jensen, T. B., Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Høgh, A. M., Eugen-Olsen, J. & Bukh, Jens, 2008, In: Journal of Infectious Diseases. 198, 12, p. 1756-1765 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    70. 2007
    71. Published

      Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses

      Gottwein, J. M., Scheel, Troels Kasper Høyer, Hoegh, A. M., Lademann, J. B., Eugen-Olsen, J., Lisby, G. & Bukh, Jens, 2007, In: Gastroenterology. 133, 5, p. 1614-26 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    72. 2006
    73. Published

      Development and validation of a multiplex add-on assay for sepsis biomarkers using xMAP technology

      Kofoed, K., Schneider, U. V., Scheel, Troels Kasper Høyer, Andersen, Ove & Eugen-Olsen, J., Jul 2006, In: Clinical Chemistry. 52, 7, p. 1284-93 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 3511922