Troels Kasper Høyer Scheel

Troels Kasper Høyer Scheel

Associate Professor, Associate Professor - Promotion Programme

Member of:


    1. 2024
    2. Published

      Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice

      Brown, A. J., Won, J. J., Wolfisberg, R., Fahnøe, U., Catanzaro, N., West, A., Moreira, F. R., Nogueira Batista, M., Ferris, M. T., Linnertz, C. L., Leist, S. R., Nguyen, C., De La Cruz, G., Midkiff, B. R., Xia, Y., Evangelista, M. D., Montgomery, S. A., Billerbeck, E., Bukh, J., Scheel, T. K. H. & 2 others, Rice, C. M. & Sheahan, T. P., 2024, In: Hepatology. 79, 1, p. 183-197

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. 2023
    4. Published

      Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease

      Mullari, M., Fossat, Nicolas Julien, Skotte, Niels Henning, Asenjo-Martinez, A., Humphreys, D. T., Bukh, Jens, Kirkeby, Agnete, Scheel, Troels Kasper Høyer & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 20 p., 4348.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Differential activity of nucleotide analogs against tick-borne encephalitis and yellow fever viruses in human cell lines

      Binderup, A., Galli, Andrea, Fossat, Nicolas Julien, Fernandez-Antunez, C., Mikkelsen, L. S., Rivera, Lizandro, Scheel, Troels Kasper Høyer, Fahnøe, Ulrik, Bukh, Jens & Ramirez, S., 2023, In: Virology. 585, p. 179-185 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide

      Sherwood, A. V., Rivera-Rangel, L. R., Ryberg, L. A., Larsen, H. S., Anker, K. M., Costa, R., Vågbø, C. B., Jakljevič, E., Pham, L. V., Fernandez-Antunez, C., Indrisiunaite, G., Podolska-Charlery, A., Grothen, J. E. R., Langvad, N. W., Fossat, N., Offersgaard, A., Al-Chaer, A., Nielsen, L., Kuśnierczyk, A., Sølund, C. & 8 others, Weis, Nina, Gottwein, Judith Margarete, Holmbeck, Kenn, Bottaro, S., Ramirez Almeida, Santseharay, Bukh, Jens, Scheel, Troels Kasper Høyer & Vinther, Jeppe, 2023, In: Nature. 619, p. 811-818

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Identification of the viral and cellular microRNA interactomes during SARS-CoV-2 infection

      Fossat, Nicolas Julien, Lundsgaard, Emma Alberte, Costa, Rui, Rivera, Lizandro, Nielsen, L., Mikkelsen, L. S., Ramirez Almeida, Santseharay, Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Cell Reports. 42, 4, 112282.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Molecular Determinants of Mouse Adaptation of Rat Hepacivirus

      Wolfisberg, R., Holmbeck, Kenn, Billerbeck, E., Thorselius, Caroline Eva, Batista, M. N., Fahnøe, Ulrik, Lundsgaard, Emma Alberte, Kennedy, Matthew James, Nielsen, L., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Journal of Virology. 97, 4, 17 p., e0181222.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. 2022
    10. Published

      Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals

      Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P., Ramirez Almeida, S. & 4 others, Reichl, U., Genzel, Y., Bukh, Jens & Gottwein, Judith Margarete, 6 Jul 2022.

      Research output: Contribution to conferencePosterCommunication

    11. Published

      Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals

      Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Holmbeck, K., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P. & 5 others, Ramirez Almeida, Santseharay, Reichl, U., Genzel, Y., Bukh, J. & Gottwein, Judith Margarete, 6 Jul 2022.

      Research output: Contribution to conferenceConference abstract for conferenceCommunication

    12. Published

      A distinct dexamethasone-dependent gene expression profile in the lungs of COVID-19 patients

      Fahnøe, Ulrik, Ronit, A., Berg, Ronan Martin Griffin, Jørgensen, S. E., Mogensen, T. H., Underwood, Alexander Paul James, Scheel, Troels Kasper Høyer, Bukh, Jens & Plovsing, R. R., 2022, In: The Journal of Infectious Diseases. 226, 12, p. 2137–2141

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Neutralization and receptor use of infectious culture–derived rat hepacivirus as a model for HCV

      Wolfisberg, R., Thorselius, Caroline Eva, Salinas, E., Elrod, E., Trivedi, S., Nielsen, L., Fahnøe, Ulrik, Kapoor, A., Grakoui, A., Rice, C. M., Bukh, Jens, Holmbeck, Kenn & Scheel, Troels Kasper Høyer, 2022, In: Hepatology. 76, 5, p. 1506-1519

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and Replication

      Fahnøe, Ulrik, Pham, Long, Fernandez-Antunez, C., Costa, Rui, Rivera, Lizandro, Galli, Andrea, Feng, S., Mikkelsen, L. S., Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay & Bukh, Jens, 2022, In: Viruses. 14, 2, 172.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. 2021
    16. Published

      Argonaute-CLIP delineates versatile, functional RNAi networks in Aedes aegypti, a major vector of human viruses

      Rozen-Gagnon, K., Gu, M., Luna, J. M., Luo, J., Yi, S., Novack, S., Jacobson, E., Wang, W., Paul, M. R., Scheel, Troels Kasper Høyer, Carroll, T. & Rice, C. M., 2021, In: Cell Host & Microbe. 29, 5, p. 834-848

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 in Vitro

      Gammeltoft, Karen Anbro, Zhou, Y., Duarte Hernandez, C. R., Galli, Andrea, Offersgaard, Anna Falden, Costa, Rui, Pham, Long, Fahnøe, Ulrik, Feng, S., Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2021, In: Antimicrobial Agents and Chemotherapy. 65, 9, e02680-20.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Pathogenesis, miR-122 gene-regulation, and protective immune responses after acute equine hepacivirus infection

      Tomlinson, J. E., Wolfisberg, R., Fahnøe, Ulrik, Patel, R. S., Trivedi, S., Kumar, A., Sharma, H., Nielsen, L., McDonough, S. P., Bukh, Jens, Tennant, B. C., Kapoor, A., Rosenberg, B. R., Rice, C. M., Divers, T. J., Van de Walle, G. R. & Scheel, Troels Kasper Høyer, 2021, In: Hepatology. 74, 3, p. 1148-1163

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Sars-cov-2 production in a scalable high cell density bioreactor

      Offersgaard, Anna Falden, Hernandez, C. R. D., Pihl, A. F., Costa, Rui, Venkatesan, N. P., Lin, X., Pham, Long, Feng, S., Fahnøe, Ulrik, Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Reichl, U., Bukh, Jens, Genzel, Y. & Gottwein, Judith Margarete, 2021, In: Vaccines. 9, 7, 706.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. 2020
    21. Published

      Evolutionary selection of pestivirus variants with altered or no microRNA dependency

      Kokkonos, K. G., Fossat, Nicolas Julien, Nielsen, L., Holm, C., Hepkema, W. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 4 Jun 2020, In: Nucleic Acids Research. 48, 10, p. 5555-5571 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Equine pegiviruses cause persistent infection of bone marrow and are not associated with hepatitis

      Tomlinson, J. E., Wolfisberg, R., Fahnøe, Ulrik, Sharma, H., Renshaw, R. W., Nielsen, L., Nishiuchi, E., Holm, C., Dubovi, E., Rosenberg, B. R., Tennant, B. C., Bukh, Jens, Kapoor, A., Divers, T. J., Rice, C. M., Van de Walle, G. R. & Scheel, Troels Kasper Høyer, 2020, In: P L o S Pathogens. 16, 7, 23 p., e1008677.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. 2019
    24. Published

      Functional Interplay between RNA Viruses and Non-Coding RNA in Mammals

      Damas, N. D., Fossat, Nicolas Julien & Scheel, Troels Kasper Høyer, 14 Jan 2019, In: Non-coding RNA. 5, 1, 7.

      Research output: Contribution to journalReviewResearchpeer-review

    25. Published

      Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells

      Wolfisberg, R., Holmbeck, Kenn, Nielsen, L., Kapoor, A., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2019, In: Journal of Virology. 93, 19, 19 p., e00733-19.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. 2018
    27. Published

      Viral persistence, liver disease, and host response in a hepatitis C–like virus rat model

      Trivedi, S., Murthy, S., Sharma, H., Hartlage, A. S., Kumar, A., Gadi, S. V., Simmonds, P., Chauhan, L. V., Scheel, Troels Kasper Høyer, Billerbeck, E., Burbelo, P. D., Rice, C. M., Lipkin, W. I., Vandegrift, K., Cullen, J. M. & Kapoor, A., 1 Aug 2018, In: Hepatology. 68, 2, p. 435-448 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Efficacy of NS5A Inhibitors Against Hepatitis C Virus Genotypes 1–7 and Escape Variants

      Gottwein, Judith Margarete, Pham, Long, Mikkelsen, L. S., Ghanem, L., Ramirez Almeida, Santseharay, Scheel, Troels Kasper Høyer, Carlsen, T. H. R. & Bukh, Jens, Apr 2018, In: Gastroenterology. 154, 5, p. 1435-1448 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product

      Divers, T. J., Tennant, B. C., Kumar, A., McDonough, S., Cullen, J., Bhuva, N., Jain, K., Chauhan, L. S., Scheel, Troels Kasper Høyer, Lipkin, W. I., Laverack, M., Trivedi, S., Srinivasa, S., Beard, L., Rice, C. M., Burbelo, P. D., Renshaw, R. W., Dubovi, E. & Kapoor, A., Feb 2018, In: Emerging Infectious Diseases . 24, 2, p. 303-310 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. 2017
    31. Published

      Global mapping of miRNA-target interactions in cattle (Bos taurus)

      Scheel, Troels Kasper Høyer, Moore, M. J., Luna, J. M., Nishiuchi, E., Fak, J., Darnell, R. B. & Rice, C. M., 2017, In: Scientific Reports. 7, 1, 13 p., 8190.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Mouse models of acute and chronic hepacivirus infection

      Billerbeck, E., Wolfisberg, R., Fahnøe, Ulrik, Xiao, J. W., Quirk, C., Luna, J. M., Cullen, J. M., Hartlage, A. S., Chiriboga, L., Ghoshal, K., Lipkin, W. I., Bukh, Jens, Scheel, Troels Kasper Høyer, Kapoor, A. & Rice, C. M., 2017, In: Science. 357, 6347, p. 204-208 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence

      Yu, Y., Scheel, Troels Kasper Høyer, Luna, J. M., Chung, H., Nishiuchi, E., Scull, M. A., Echeverría, N., Ricardo-Lax, I., Kapoor, A., Lipkin, I. W., Divers, T. J., Antczak, D. F., Tennant, B. C. & Rice, C. M., 2017, In: PLOS Pathogens. 13, 10, 21 p., e1006694.

      Research output: Contribution to journalJournal articleResearchpeer-review

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    ID: 3511922