Troels Kasper Høyer Scheel
Associate Professor, Associate Professor - Promotion Programme
Virology
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-13-84
Member of:
- 2024
- Published
Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice
Brown, A. J., Won, J. J., Wolfisberg, R., Fahnøe, U., Catanzaro, N., West, A., Moreira, F. R., Nogueira Batista, M., Ferris, M. T., Linnertz, C. L., Leist, S. R., Nguyen, C., De La Cruz, G., Midkiff, B. R., Xia, Y., Evangelista, M. D., Montgomery, S. A., Billerbeck, E., Bukh, J., Scheel, T. K. H. & 2 others, , 2024, In: Hepatology. 79, 1, p. 183-197Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease
Mullari, M., Fossat, Nicolas Julien, Skotte, Niels Henning, Asenjo-Martinez, A., Humphreys, D. T., Bukh, Jens, Kirkeby, Agnete, Scheel, Troels Kasper Høyer & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 20 p., 4348.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential activity of nucleotide analogs against tick-borne encephalitis and yellow fever viruses in human cell lines
Binderup, A., Galli, Andrea, Fossat, Nicolas Julien, Fernandez-Antunez, C., Mikkelsen, L. S., Rivera, Lizandro, Scheel, Troels Kasper Høyer, Fahnøe, Ulrik, Bukh, Jens & Ramirez, S., 2023, In: Virology. 585, p. 179-185 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide
Sherwood, A. V., Rivera-Rangel, L. R., Ryberg, L. A., Larsen, H. S., Anker, K. M., Costa, R., Vågbø, C. B., Jakljevič, E., Pham, L. V., Fernandez-Antunez, C., Indrisiunaite, G., Podolska-Charlery, A., Grothen, J. E. R., Langvad, N. W., Fossat, N., Offersgaard, A., Al-Chaer, A., Nielsen, L., Kuśnierczyk, A., Sølund, C. & 8 others, , 2023, In: Nature. 619, p. 811-818Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of the viral and cellular microRNA interactomes during SARS-CoV-2 infection
Fossat, Nicolas Julien, Lundsgaard, Emma Alberte, Costa, Rui, Rivera, Lizandro, Nielsen, L., Mikkelsen, L. S., Ramirez Almeida, Santseharay, Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Cell Reports. 42, 4, 112282.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Determinants of Mouse Adaptation of Rat Hepacivirus
Wolfisberg, R., Holmbeck, Kenn, Billerbeck, E., Thorselius, Caroline Eva, Batista, M. N., Fahnøe, Ulrik, Lundsgaard, Emma Alberte, Kennedy, Matthew James, Nielsen, L., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Journal of Virology. 97, 4, 17 p., e0181222.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals
Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P., Ramirez Almeida, S. & 4 others, , 6 Jul 2022.Research output: Contribution to conference › Poster › Communication
- Published
Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals
Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Holmbeck, K., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P. & 5 others, , 6 Jul 2022.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
A distinct dexamethasone-dependent gene expression profile in the lungs of COVID-19 patients
Fahnøe, Ulrik, Ronit, A., Berg, Ronan Martin Griffin, Jørgensen, S. E., Mogensen, T. H., Underwood, Alexander Paul James, Scheel, Troels Kasper Høyer, Bukh, Jens & Plovsing, R. R., 2022, In: The Journal of Infectious Diseases. 226, 12, p. 2137–2141Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutralization and receptor use of infectious culture–derived rat hepacivirus as a model for HCV
Wolfisberg, R., Thorselius, Caroline Eva, Salinas, E., Elrod, E., Trivedi, S., Nielsen, L., Fahnøe, Ulrik, Kapoor, A., Grakoui, A., Rice, C. M., Bukh, Jens, Holmbeck, Kenn & Scheel, Troels Kasper Høyer, 2022, In: Hepatology. 76, 5, p. 1506-1519Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and Replication
Fahnøe, Ulrik, Pham, Long, Fernandez-Antunez, C., Costa, Rui, Rivera, Lizandro, Galli, Andrea, Feng, S., Mikkelsen, L. S., Gottwein, Judith Margarete, Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay & Bukh, Jens, 2022, In: Viruses. 14, 2, 172.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Argonaute-CLIP delineates versatile, functional RNAi networks in Aedes aegypti, a major vector of human viruses
Rozen-Gagnon, K., Gu, M., Luna, J. M., Luo, J., Yi, S., Novack, S., Jacobson, E., Wang, W., Paul, M. R., Scheel, Troels Kasper Høyer, Carroll, T. & Rice, C. M., 2021, In: Cell Host & Microbe. 29, 5, p. 834-848Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 in Vitro
Gammeltoft, Karen Anbro, Zhou, Y., Duarte Hernandez, C. R., Galli, Andrea, Offersgaard, Anna Falden, Costa, Rui, Pham, Long, Fahnøe, Ulrik, Feng, S., Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2021, In: Antimicrobial Agents and Chemotherapy. 65, 9, e02680-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathogenesis, miR-122 gene-regulation, and protective immune responses after acute equine hepacivirus infection
Tomlinson, J. E., Wolfisberg, R., Fahnøe, Ulrik, Patel, R. S., Trivedi, S., Kumar, A., Sharma, H., Nielsen, L., McDonough, S. P., Bukh, Jens, Tennant, B. C., Kapoor, A., Rosenberg, B. R., Rice, C. M., Divers, T. J., Van de Walle, G. R. & Scheel, Troels Kasper Høyer, 2021, In: Hepatology. 74, 3, p. 1148-1163Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sars-cov-2 production in a scalable high cell density bioreactor
Offersgaard, Anna Falden, Hernandez, C. R. D., Pihl, A. F., Costa, Rui, Venkatesan, N. P., Lin, X., Pham, Long, Feng, S., Fahnøe, Ulrik, Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Reichl, U., Bukh, Jens, Genzel, Y. & Gottwein, Judith Margarete, 2021, In: Vaccines. 9, 7, 706.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Evolutionary selection of pestivirus variants with altered or no microRNA dependency
Kokkonos, K. G., Fossat, Nicolas Julien, Nielsen, L., Holm, C., Hepkema, W. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 4 Jun 2020, In: Nucleic Acids Research. 48, 10, p. 5555-5571 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Equine pegiviruses cause persistent infection of bone marrow and are not associated with hepatitis
Tomlinson, J. E., Wolfisberg, R., Fahnøe, Ulrik, Sharma, H., Renshaw, R. W., Nielsen, L., Nishiuchi, E., Holm, C., Dubovi, E., Rosenberg, B. R., Tennant, B. C., Bukh, Jens, Kapoor, A., Divers, T. J., Rice, C. M., Van de Walle, G. R. & Scheel, Troels Kasper Høyer, 2020, In: P L o S Pathogens. 16, 7, 23 p., e1008677.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Functional Interplay between RNA Viruses and Non-Coding RNA in Mammals
Damas, N. D., Fossat, Nicolas Julien & Scheel, Troels Kasper Høyer, 14 Jan 2019, In: Non-coding RNA. 5, 1, 7.Research output: Contribution to journal › Review › Research › peer-review
- Published
Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells
Wolfisberg, R., Holmbeck, Kenn, Nielsen, L., Kapoor, A., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2019, In: Journal of Virology. 93, 19, 19 p., e00733-19.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Viral persistence, liver disease, and host response in a hepatitis C–like virus rat model
Trivedi, S., Murthy, S., Sharma, H., Hartlage, A. S., Kumar, A., Gadi, S. V., Simmonds, P., Chauhan, L. V., Scheel, Troels Kasper Høyer, Billerbeck, E., Burbelo, P. D., Rice, C. M., Lipkin, W. I., Vandegrift, K., Cullen, J. M. & Kapoor, A., 1 Aug 2018, In: Hepatology. 68, 2, p. 435-448 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of NS5A Inhibitors Against Hepatitis C Virus Genotypes 1–7 and Escape Variants
Gottwein, Judith Margarete, Pham, Long, Mikkelsen, L. S., Ghanem, L., Ramirez Almeida, Santseharay, Scheel, Troels Kasper Høyer, Carlsen, T. H. R. & Bukh, Jens, Apr 2018, In: Gastroenterology. 154, 5, p. 1435-1448 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product
Divers, T. J., Tennant, B. C., Kumar, A., McDonough, S., Cullen, J., Bhuva, N., Jain, K., Chauhan, L. S., Scheel, Troels Kasper Høyer, Lipkin, W. I., Laverack, M., Trivedi, S., Srinivasa, S., Beard, L., Rice, C. M., Burbelo, P. D., Renshaw, R. W., Dubovi, E. & Kapoor, A., Feb 2018, In: Emerging Infectious Diseases . 24, 2, p. 303-310 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Global mapping of miRNA-target interactions in cattle (Bos taurus)
Scheel, Troels Kasper Høyer, Moore, M. J., Luna, J. M., Nishiuchi, E., Fak, J., Darnell, R. B. & Rice, C. M., 2017, In: Scientific Reports. 7, 1, 13 p., 8190.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mouse models of acute and chronic hepacivirus infection
Billerbeck, E., Wolfisberg, R., Fahnøe, Ulrik, Xiao, J. W., Quirk, C., Luna, J. M., Cullen, J. M., Hartlage, A. S., Chiriboga, L., Ghoshal, K., Lipkin, W. I., Bukh, Jens, Scheel, Troels Kasper Høyer, Kapoor, A. & Rice, C. M., 2017, In: Science. 357, 6347, p. 204-208 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence
Yu, Y., Scheel, Troels Kasper Høyer, Luna, J. M., Chung, H., Nishiuchi, E., Scull, M. A., Echeverría, N., Ricardo-Lax, I., Kapoor, A., Lipkin, I. W., Divers, T. J., Antczak, D. F., Tennant, B. C. & Rice, C. M., 2017, In: PLOS Pathogens. 13, 10, 21 p., e1006694.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3511922
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264
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Global mapping of miRNA-target interactions in cattle (Bos taurus)
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
212
downloads
miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
206
downloads
Functional Interplay between RNA Viruses and Non-Coding RNA in Mammals
Research output: Contribution to journal › Review › Research › peer-review
Published