Thomas Eiland Nielsen
Affiliate Professor
Bacteriology
Nørre Allé 14
2200 København N
- 2024
- Published
High efficacytreatment of murine Pseudomonas aeruginosa catheter-associated urinary tract infections using the c-di-GMP modulating anti-biofilmcompound Disperazol in combination with ciprofloxacin
Hultqvist, Louise Dahl, Andersen, Jens Bo, Nilsson, Carl Martin Peter, Jansen, C. U., Rybtke, Morten Levin, Jakobsen, Tim Holm, Nielsen, Thomas Eiland, Qvortrup, Klaus, Moser, Claus Ernst, Graz, M., Qvortrup, K., Tolker-Nielsen, Tim & Givskov, Michael, 2024, In: Antimicrobial Agents and Chemotherapy. 68, 6, 16 p., e01481-23.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Solid-phase synthesis and biological evaluation of piperazine-based novel bacterial topoisomerase inhibitors
Flagstad, T., Pedersen, M. T., Jakobsen, Tim Holm, Felding, J., Tolker-Nielsen, Tim, Givskov, Michael, Qvortrup, K. & Nielsen, Thomas Eiland, 2022, In: Bioorganic and Medicinal Chemistry Letters. 57, 128499.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Identification of small molecules that interfere with c-di-GMP signaling and induce dispersal of Pseudomonas aeruginosa biofilms
Andersen, Jens Bo, Hultqvist, Louise Dahl, Jansen, C. U., Jakobsen, Tim Holm, Nilsson, Carl Martin Peter, Rybtke, Morten Levin, Uhd, J., Fritz, Blaine Gabriel, Seifert, R., Berthelsen, J., Nielsen, Thomas Eiland, Qvortrup, K., Givskov, Michael & Tolker-Nielsen, Tim, 2021, In: npj Biofilms and Microbiomes. 7, 13 p., 59.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SAR study of 4-arylazo-3,5-diamino-1: H -pyrazoles: identification of small molecules that induce dispersal of Pseudomonas aeruginosa biofilms
Jansen, C. U., Uhd, J., Andersen, Jens Bo, Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Nilsson, Carl Martin Peter, Nielsen, Thomas Eiland, Givskov, Michael, Tolker-Nielsen, Tim & Qvortrup, K. M., 2021, In: RSC Medicinal Chemistry. 12, 11, p. 1868-1878 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Generation of a Heteropolycyclic and sp3-Rich Scaffold for Library Synthesis from a Highly Diastereoselective Petasis/Diels–Alder and ROM–RCM Reaction Sequence
Flagstad, T., Azevedo, C. M. G., Troelsen, N. S., Min, G. K., Macé, Y., Willaume, A., Guilleux, R., Velay, M., Bonnet, K., Morgentin, R., Nielsen, Thomas Eiland & Clausen, M. H., 2019, In: European Journal of Organic Chemistry. 2019, 5, p. 1061-1076Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Itaconimides as Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa
Fong, J., Mortensen, K. T., Nørskov, A., Qvortrup, K., Yang, L., Tan, C. H., Nielsen, Thomas Eiland & Givskov, Michael, 2019, In: Frontiers in Cellular and Infection Microbiology. 11, 11 p., 433.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reactivity and Synthetic Applications of Multicomponent Petasis Reactions
Wu, P., Givskov, Michael & Nielsen, Thomas Eiland, 2019, In: Chemical Reviews. 119, 20, p. 11245-11290 46 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Small Molecule Anti-biofilm Agents Developed on the Basis of Mechanistic Understanding of Biofilm Formation
Qvortrup, K., Hultqvist, Louise Dahl, Nilsson, Carl Martin Peter, Jakobsen, Tim Holm, Jansen, C. U., Uhd, J., Andersen, Jens Bo, Nielsen, Thomas Eiland, Givskov, Michael & Tolker-Nielsen, Tim, 2019, In: Frontiers in Chemistry. 7, 27 p., 742.Research output: Contribution to journal › Review › Research › peer-review
- 2018
- Published
Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa
Fong, J., Zhang, C., Yang, R., Boo, Z. Z., Tan, S. K., Nielsen, Thomas Eiland, Givskov, Michael, Liu, X., Bin, W., Su, H. & Yang, L., 1 Dec 2018, In: Scientific Reports. 8, 11 p., 1155.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bead-based screening in chemical biology and drug discovery
Komnatnyy, V. V., Nielsen, Thomas Eiland & Qvortrup, K., 2018, In: Chemical Communications. 54, 50, p. 6759-6771 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 162434453
Most downloads
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214
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A broad range quorum sensing inhibitor working through sRNA inhibition
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
203
downloads
Small Molecule Anti-biofilm Agents Developed on the Basis of Mechanistic Understanding of Biofilm Formation
Research output: Contribution to journal › Review › Research › peer-review
Published -
168
downloads
Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa
Research output: Contribution to journal › Journal article › Research › peer-review
Published