Henrik Nyhus Kløverpris

Henrik Nyhus Kløverpris

Associate Professor


  1. 2018
  2. Published

    Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy

    Muenchhoff, M., Healy, M., Singh, R., Roider, J., Groll, A., Kindra, C., Sibaya, T., Moonsamy, A., McGregor, C., Phan, M. Q., Palma, A., Kløverpris, Henrik Nyhus, Leslie, A., Bobat, R., Larussa, P., Ndung'U, T., Goulder, P., Sobieszczyk, M. E. & Archary, M., Jan 2018, In: AIDS Research and Human Retroviruses. 34, 1, p. 46-55 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    High-frequency, functional HIV-specific T-follicular helper and regulatory cells are present within germinal centers in children but not adults

    Roider, J., Maehara, T., Ngoepe, A., Ramsuran, D., Muenchhoff, M., Adland, E., Aicher, T., Kazer, S. W., Jooste, P., Karim, F., Kuhn, W., Shalek, A. K., Ndung'u, T., Morris, L., Moore, P. L., Pillai, S., Kløverpris, Henrik Nyhus, Goulder, P. & Leslie, A., 2018, In: Frontiers in Immunology. 9, 14 p., 1975.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells

    Attaf, M., Malik, A., Severinsen, M. C., Roider, J., Ogongo, P., Buus, Søren, Ndung'u, T., Leslie, A., Kløverpris, Henrik Nyhus, Matthews, P. C., Sewell, A. K. & Goulder, P., 2018, In: Frontiers in Immunology. 9, 2539.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2017
  6. Published

    Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

    Simoni, Y., Fehlings, M., Kloverpris, H. N., McGovern, N., Koo, S-L., Loh, C. Y., Lim, S., Kurioka, A., Fergusson, J. R., Tang, C-L., Kam, M. H., Dennis, K., Lim, T. K. H., Fui, A. C. Y., Hoong, C. W., Chan, J. K. Y., de Lafaille, M. C., Narayanan, S., Baig, S., Shabeer, M. & 11 others, Toh, S. E. S., Tan, H. K. K., Anicete, R., Tan, E., Takano, A., Klenerman, P., Leslie, A., Tan, D. S. W., Tan, I. B., Ginhoux, F. & Newell, E. W., 17 Jan 2017, In: Immunity. 46, 1, p. 148-161

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Immunodominant cytomegalovirus-specific CD8+ T-cell responses in sub-Saharan African populations

    Malik, A., Adland, E., Laker, L., Kløverpris, Henrik Nyhus, Fardoos, R., Roider, J., Severinsen, M. C., Chen, F., Riddell, L., Edwards, A., Buus, Søren, Jooste, P., Matthews, P. C. & Goulder, P. J. R., 2017, In: PLOS ONE. 12, 12, 15 p., e0189612.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2016
  9. Published

    Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

    Muenchhoff, M., Adland, E., Karimanzira, O., Crowther, C., Pace, M., Csala, A., Leitman, E., Moonsamy, A., McGregor, C., Hurst, J., Groll, A., Mori, M., Sinmyee, S., Thobakgale, C., Tudor-Williams, G., Prendergast, A. J., Kloverpris, H., Roider, J., Leslie, A., Shingadia, D. & 10 others, Brits, T., Daniels, S., Frater, J., Willberg, C. B., Walker, B. D., Ndung'u, T., Jooste, P., Moore, P. L., Morris, L. & Goulder, P., 28 Sep 2016, In: Science Translational Medicine. 8, 358, 15 p., 358ra125.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-Infection in the Absence of Viral Suppression

    Kløverpris, H. N., Kazer, S. W., Mjösberg, J., Mabuka, J. M., Wellmann, A., Ndhlovu, Z., Yadon, M. C., Nhamoyebonde, S., Muenchhoff, M., Simoni, Y., Andersson, F., Kuhn, W., Garrett, N., Burgers, W. A., Kamya, P., Pretorius, K., Dong, K., Moodley, A., Newell, E. W., Kasprowicz, V. & 6 others, Abdool Karim, S. S., Goulder, P., Shalek, A. K., Walker, B. D., Ndung'u, T. & Leslie, A., 16 Feb 2016, In: Immunity. 44, 2, p. 391-405 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Human T cell responses to Japanese encephalitis virus in health and disease

    Turtle, L., Bali, T., Buxton, G., Chib, S., Chan, S., Soni, M., Hussain, M., Isenman, H., Fadnis, P., Venkataswamy, M. M., Satishkumar, V., Lewthwaite, P., Kurioka, A., Krishna, S., Shankar, M. V., Ahmed, R., Begum, A., Ravi, V., Desai, A., Yoksan, S. & 7 others, Fernandez, S., Willberg, C. B., Kløverpris, Henrik Nyhus, Conlon, C., Klenerman, P., Satchidanandam, V. & Solomon, T., 2016, In: Journal of Experimental Medicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells

    Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells

    Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Role of HLA adaptation in HIV evolution

    Kløverpris, Henrik Nyhus, Leslie, A. & Goulder, P., 2016, In: Frontiers in Immunology. 6, 15 p., 665.

    Research output: Contribution to journalReviewResearchpeer-review

  15. 2015
  16. Published

    Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

    Ndhlovu, Z. M., Kamya, P., Mewalal, N., Kloverpris, H. N., Nkosi, T., Pretorius, K., Laher, F., Ogunshola, F., Chopera, D., Shekhar, K., Ghebremichael, M., Ismail, N., Moodley, A., Malik, A., Leslie, A., Goulder, P. J. R., Buus, S., Chakraborty, A., Dong, K., Ndung'u, T. & 1 others, Walker, B. D., 15 Sep 2015, In: Immunity. 43, 3, p. 591-604 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    CD8+ TCR Bias and Immunodominance in HIV-1 Infection

    Kløverpris, Henrik Nyhus, McGregor, R., McLaren, J. E., Ladell, K., Harndahl, M., Buus, Anette Stryhn, Carlson, J. M., Koofhethile, C., Gerritsen, B., Kesmir, C., Chen, F., Riddell, L., Luzzi, G., Leslie, A., Walker, B. D., Ndung'u, T., Buus, Søren, Price, D. A. & Goulder, P. J., 1 Jun 2015, In: Journal of Immunology. 194, 11, p. 5329-5345 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Human and Murine Clonal CD8+T Cell Expansions Arise during Tuberculosis Because of TCR Selection

    Nunes-Alves, C., Booty, M. G., Carpenter, S. M., Rothchild, A. C., Martin, C. J., Desjardins, D., Steblenko, K., Kløverpris, Henrik Nyhus, Madansein, R., Ramsuran, D., Leslie, A., Correia-Neves, M. & Behar, S. M., May 2015, In: P L o S Pathogens. 11, 5, p. 1-29 29 p., e1004849.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape

    Kløverpris, Henrik Nyhus, Cole, D. K., Fuller, A., Carlson, J., Beck, K., Schauenburg, A. J., Rizkallah, P. J., Buus, Søren, Sewell, A. K. & Goulder, P., 20 Feb 2015, In: Retrovirology. 12, p. 1-11 11 p., 20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2014
  21. Published

    Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load

    Kløverpris, Henrik Nyhus, McGregor, R., McLaren, J. E., Ladell, K., Buus, Anette Stryhn, Koofhethile, C., Brener, J., Chen, F., Riddell, L., Graziano, L., Klenerman, P., Leslie, A., Buus, Søren, Price, D. A. & Goulder, P., 10 Sep 2014, In: AIDS (London, England). 28, 14, p. 2007-21 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    HIV subtype influences HLA-B*07:02-associated HIV disease outcome

    Kløverpris, Henrik Nyhus, Adland, E., Koyanagi, M., Buus, Anette Stryhn, Harndahl, M., Matthews, P. C., Shapiro, R., Walker, B. D., Ndung'u, T., Brander, C., Takiguchi, M., Buus, Søren & Goulder, P., May 2014, In: AIDS Research and Human Retroviruses. 30, 5, p. 468-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Differential escape patterns within the dominant HLA-B*57:03-restricted HIV gag epitope reflect distinct clade-specific functional constraints

    Payne, R. P., Branch, S., Kløverpris, H., Matthews, P. C., Koofhethile, C. K., Strong, T., Adland, E., Leitman, E., Frater, J., Ndung'u, T., Hunter, E., Haubrich, R., Mothe, B., Edwards, A., Riddell, L., Chen, F., Harrigan, P. R., Brumme, Z. L., Mallal, S., John, M. & 9 others, Jooste, J. P., Shapiro, R., Deeks, S. G., Walker, B. D., Brander, C., Landis, C., Carlson, J. M., Prado, J. G. & Gouldera, P. J. R., 2014, In: Journal of Virology. 88, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2013
  25. Published

    HLA-A*68:02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective

    Kløverpris, Henrik Nyhus, Buus, Anette Stryhn, Harndahl, M., Carlson, J. M., Leslie, A. J., Chen, F., Riddell, L., Mulenga, J., Walker, B. D., Ndung'u, T., Buus, Søren & Goulder, P., 17 Jul 2013, In: AIDS (London, England). 27, 11, p. 1717-23 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A Randomised, Placebo-Controlled, First-In-Human Study of a Novel Clade C Therapeutic Peptide Vaccine Administered Ex Vivo to Autologous White Blood Cells in HIV Infected Individuals

    Jackson, Andrew D., Kløverpris, Henrik Nyhus, Boffito, M., Handley, A., Atkins, M., Hayes, P., Gilmour, J., Riddel, L., Chen, F., Bailey-Tippets, M., Walker, B., Ackland, J., Sullivan, M. & Goulder, P., 2013, In: PLoS ONE.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    CD8αα expression marks terminally differentiated human CD8+ T cells expanded in chronic viral infection

    Walker, L. J., Marrinan, E., Muenchhoff, M., Ferguson, J., Kløverpris, Henrik Nyhus, Cheroutre, H., Barnes, E., Goulder, P. & Klenerman, P., 2013, In: Frontiers in Immunology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T Cells

    Kløverpris, Henrik Nyhus, Payne, R. P., Sacha, J. B., Rasaiyaah, J. T., Chen, F., Takiguchi, M., Yang, O. O., Towers, G. J., Goulder, P. & Prado, J. G., 2013, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01

    Kløverpris, Henrik Nyhus, Stryhn, A., Harndahl, M., Payne, R., Towers, G. J., Chen, F., Riddell, L., Walker, B. D., Ndung'u, T., Leslie, A., Buus, Søren & Goulder, P., 2013, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Nef-specific CD8+ T cell responses contribute to HIV-1 immune control

    Adland, E., Carlson, J. M., Paioni, P., Kløverpris, Henrik Nyhus, Shapiro, R., Ogwu, A., Riddell, L., Luzzi, G., Chen, F., Balachandran, T., Heckerman, D., Stryhn, A., Edwards, A., Ndung'u, T., Walker, B. D., Buus, Søren, Goulder, P. & Matthews, P. C., 2013, In: PLoS ONE. 8, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Non-Immunogenicity of Overlapping Gag Peptides Pulsed on Autologous Cells after Vaccination of HIV Infected Individuals

    Kløverpris, Henrik Nyhus, Jackson, Andrew D., Handley, A., Hayes, P., Gilmour, J., Riddell, L., Chen, F., Atkins, M., Boffito, M., Walker, B. D., Ackland, J., Sullivan, M. & Goulder, P., 2013, In: PLoS ONE.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 43835678