Henrik Nyhus Kløverpris

Henrik Nyhus Kløverpris

Associate Professor


  1. 2007
  2. Published

    Sequence conservation of subdominant HLA-A2-binding CTL epitopes in HIV-1 clinical isolates and CD8<sup>+</sup> T-lymphocyte cross-recognition may explain the immune reaction in infected individuals

    Thorn, M., Tang, S., Therrien, D., Kløverpris, Henrik Nyhus, Vinner, Lasse, Kronborg, Gitte, Gerstoft, Jan, Corbet, S. & Fomsgaard, A., 2007, In: APMIS.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Sequence conservation of subdominant HLA-A2-binding CTL epitopes in HIV-1 clinical isolates and CD8<sup>+</sup> T-lymphocyte cross-recognition may explain the immune reaction in infected individuals

    Thorn, M., Tang, S., Therrien, D., Kløverpris, Henrik Nyhus, Vinner, Lasse, Kronborg, Gitte, Gerstoft, Jan, Corbet, S. & Fomsgaard, A., 2007, In: APMIS.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Sequence conservation of subdominant HLA-A2-binding CTL epitopes in HIV-1 clinical isolates and CD8<sup>+</sup> T-lymphocyte cross-recognition may explain the immune reaction in infected individuals

    Thorn, M., Tang, S., Therrien, D., Kløverpris, Henrik Nyhus, Vinner, Lasse, Kronborg, Gitte, Gerstoft, Jan, Corbet, S. & Fomsgaard, A., 2007, In: APMIS.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2010
  6. Published

    Efficacious early antiviral activity of HIV Gag- and Pol-specific HLA-B*2705-restricted CD8+ T cells

    Payne, R. P., Kløverpris, Henrik Nyhus, Sacha, J. B., Brumme, Z., Brumme, C., Buus, Søren, Sims, S., Hickling, S., Riddell, L., Chen, F., Luzzi, G., Edwards, A., Phillips, R., Prado, J. G. & Goulder, P. J. R., 2010, In: Journal of Virology. 84, 20, p. 10543-10557

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Dimethyl sulfoxide (DMSO) exposure to human peripheral blood mononuclear cells (PBMCs) abolish T cell responses only in high concentrations and following coincubation for more than two hours

    Kløverpris, Henrik Nyhus, Fomsgaard, A., Handley, A., Ackland, J., Sullivan, M. & Goulder, P., Apr 2010, In: Journal of Immunological Methods. 356, 1-2, p. 70-78 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2011
  9. Published

    High frequency, sustained T cell responses to PARV4 suggest viral persistence in vivo

    Simmons, R., Sharp, C., Sims, S., Kløverpris, Henrik Nyhus, Goulder, P., Simmonds, P., Bowness, P. & Klenerman, P., 2011, In: Journal of Infectious Diseases.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Sequence analysis of HIV-1 isolates from Guinea-Bissau: Selection of vaccine epitopes relevant in both West African and European countries

    Vinner, Lasse, Holmgren, B., Jensen, K. J., Esbjornsson, J., Borggren, M., Hentze, J. L., Karlsson, I., Andresen, B. S., Gram, G. J., Kløverpris, Henrik Nyhus, Aaby, P., da Silva, Z. J., Fenyö, E. & Fomsgaard, A., 2011, In: APMIS. 119, 8, p. 487-497

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2012
  12. Published

    HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunogenicity, selection pressure, and HIV immune control

    Kløverpris, Henrik Nyhus, Buus, Anette Stryhn, van der Stok, M., Harndahl, M., Payne, R. P., Matthews, P. C., Chen, F., Riddell, L., Walker, B. D., Ndung'u, T., Buus, Søren & Goulder, P., 2012, In: Journal of Virology. 86, 2, p. 919-29 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    HIV control through a single nucleotide on the HLA-B locus

    Kløverpris, Henrik Nyhus, Harndahl, M., Leslie, A. J., Carlson, J. M., Ismail, N., van der Stok, M., Huang, K. G., Chen, F., Riddell, L., Steyn, D., Goedhals, D., van Vuuren, C., Frater, J., Walker, B. D., Carrington, M., Ndung'u, T., Buus, Søren & Goulder, P., Nov 2012, In: Journal of Virology. 86, 21, p. 11493-11500 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Identification of conserved subdominant HIV Type 1 CD8(+) T Cell epitopes restricted within common HLA Supertypes for therapeutic HIV Type 1 vaccines

    Karlsson, I., Kløverpris, Henrik Nyhus, Jensen, K. J., Buus, Anette Stryhn, Buus, Søren, Karlsson, A., Vinner, L., Goulder, P. & Fomsgaard, A., Nov 2012, In: AIDS Research and Human Retroviruses. 28, 11, p. 1434-1443 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope

    Matthews, P. C., Koyanagi, M., Kløverpris, H. N., Harndahl, M., Buus, A. S., Akahoshi, T., Gatanaga, H., Oka, S., Juarez Molina, C., Valenzuela Ponce, H., Avila Rios, S., Cole, D., Carlson, J., Payne, R. P., Ogwu, A., Bere, A., Ndung'u, T., Gounder, K., Chen, F., Riddell, L. & 11 others, Luzzi, G., Shapiro, R., Brander, C., Walker, B., Sewell, A. K., Reyes Teran, G., Heckerman, D., Hunter, E., Buus, Søren, Takiguchi, M. & Goulder, P. J. R., Dec 2012, In: Journal of Virology. 86, 23, p. 12643-12654 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2013
  17. Published

    A Randomised, Placebo-Controlled, First-In-Human Study of a Novel Clade C Therapeutic Peptide Vaccine Administered Ex Vivo to Autologous White Blood Cells in HIV Infected Individuals

    Jackson, Andrew D., Kløverpris, Henrik Nyhus, Boffito, M., Handley, A., Atkins, M., Hayes, P., Gilmour, J., Riddel, L., Chen, F., Bailey-Tippets, M., Walker, B., Ackland, J., Sullivan, M. & Goulder, P., 2013, In: PLoS ONE.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    CD8αα expression marks terminally differentiated human CD8+ T cells expanded in chronic viral infection

    Walker, L. J., Marrinan, E., Muenchhoff, M., Ferguson, J., Kløverpris, Henrik Nyhus, Cheroutre, H., Barnes, E., Goulder, P. & Klenerman, P., 2013, In: Frontiers in Immunology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T Cells

    Kløverpris, Henrik Nyhus, Payne, R. P., Sacha, J. B., Rasaiyaah, J. T., Chen, F., Takiguchi, M., Yang, O. O., Towers, G. J., Goulder, P. & Prado, J. G., 2013, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01

    Kløverpris, Henrik Nyhus, Stryhn, A., Harndahl, M., Payne, R., Towers, G. J., Chen, F., Riddell, L., Walker, B. D., Ndung'u, T., Leslie, A., Buus, Søren & Goulder, P., 2013, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Nef-specific CD8+ T cell responses contribute to HIV-1 immune control

    Adland, E., Carlson, J. M., Paioni, P., Kløverpris, Henrik Nyhus, Shapiro, R., Ogwu, A., Riddell, L., Luzzi, G., Chen, F., Balachandran, T., Heckerman, D., Stryhn, A., Edwards, A., Ndung'u, T., Walker, B. D., Buus, Søren, Goulder, P. & Matthews, P. C., 2013, In: PLoS ONE. 8, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Non-Immunogenicity of Overlapping Gag Peptides Pulsed on Autologous Cells after Vaccination of HIV Infected Individuals

    Kløverpris, Henrik Nyhus, Jackson, Andrew D., Handley, A., Hayes, P., Gilmour, J., Riddell, L., Chen, F., Atkins, M., Boffito, M., Walker, B. D., Ackland, J., Sullivan, M. & Goulder, P., 2013, In: PLoS ONE.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    HLA-A*68:02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective

    Kløverpris, Henrik Nyhus, Buus, Anette Stryhn, Harndahl, M., Carlson, J. M., Leslie, A. J., Chen, F., Riddell, L., Mulenga, J., Walker, B. D., Ndung'u, T., Buus, Søren & Goulder, P., 17 Jul 2013, In: AIDS (London, England). 27, 11, p. 1717-23 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2014
  25. Differential escape patterns within the dominant HLA-B*57:03-restricted HIV gag epitope reflect distinct clade-specific functional constraints

    Payne, R. P., Branch, S., Kløverpris, H., Matthews, P. C., Koofhethile, C. K., Strong, T., Adland, E., Leitman, E., Frater, J., Ndung'u, T., Hunter, E., Haubrich, R., Mothe, B., Edwards, A., Riddell, L., Chen, F., Harrigan, P. R., Brumme, Z. L., Mallal, S., John, M. & 9 others, Jooste, J. P., Shapiro, R., Deeks, S. G., Walker, B. D., Brander, C., Landis, C., Carlson, J. M., Prado, J. G. & Gouldera, P. J. R., 2014, In: Journal of Virology. 88, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    HIV subtype influences HLA-B*07:02-associated HIV disease outcome

    Kløverpris, Henrik Nyhus, Adland, E., Koyanagi, M., Buus, Anette Stryhn, Harndahl, M., Matthews, P. C., Shapiro, R., Walker, B. D., Ndung'u, T., Brander, C., Takiguchi, M., Buus, Søren & Goulder, P., May 2014, In: AIDS Research and Human Retroviruses. 30, 5, p. 468-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load

    Kløverpris, Henrik Nyhus, McGregor, R., McLaren, J. E., Ladell, K., Buus, Anette Stryhn, Koofhethile, C., Brener, J., Chen, F., Riddell, L., Graziano, L., Klenerman, P., Leslie, A., Buus, Søren, Price, D. A. & Goulder, P., 10 Sep 2014, In: AIDS (London, England). 28, 14, p. 2007-21 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2015
  29. Published

    A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape

    Kløverpris, Henrik Nyhus, Cole, D. K., Fuller, A., Carlson, J., Beck, K., Schauenburg, A. J., Rizkallah, P. J., Buus, Søren, Sewell, A. K. & Goulder, P., 20 Feb 2015, In: Retrovirology. 12, p. 1-11 11 p., 20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Human and Murine Clonal CD8+T Cell Expansions Arise during Tuberculosis Because of TCR Selection

    Nunes-Alves, C., Booty, M. G., Carpenter, S. M., Rothchild, A. C., Martin, C. J., Desjardins, D., Steblenko, K., Kløverpris, Henrik Nyhus, Madansein, R., Ramsuran, D., Leslie, A., Correia-Neves, M. & Behar, S. M., May 2015, In: P L o S Pathogens. 11, 5, p. 1-29 29 p., e1004849.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    CD8+ TCR Bias and Immunodominance in HIV-1 Infection

    Kløverpris, Henrik Nyhus, McGregor, R., McLaren, J. E., Ladell, K., Harndahl, M., Buus, Anette Stryhn, Carlson, J. M., Koofhethile, C., Gerritsen, B., Kesmir, C., Chen, F., Riddell, L., Luzzi, G., Leslie, A., Walker, B. D., Ndung'u, T., Buus, Søren, Price, D. A. & Goulder, P. J., 1 Jun 2015, In: Journal of Immunology. 194, 11, p. 5329-5345 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

    Ndhlovu, Z. M., Kamya, P., Mewalal, N., Kloverpris, H. N., Nkosi, T., Pretorius, K., Laher, F., Ogunshola, F., Chopera, D., Shekhar, K., Ghebremichael, M., Ismail, N., Moodley, A., Malik, A., Leslie, A., Goulder, P. J. R., Buus, S., Chakraborty, A., Dong, K., Ndung'u, T. & 1 others, Walker, B. D., 15 Sep 2015, In: Immunity. 43, 3, p. 591-604 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 43835678