Özcan Met

Özcan Met

Visiting associate professor, Gæstelektor

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    ORCID: 0000-0002-3256-7592

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    1. Published

       of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes

      Hulen, T. M., Friese, C., Kristensen, N. P., Granhøj, J. S., Borch, T. H., Peeters, M. J. W., Donia, M., Andersen, Mads Hald, Hadrup, S. R., Svane, Inge Marie & Met, Özcan, 2023, In: Frontiers in Immunology. 14, 15 p., 1180997.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      ACT Up TIL Now: The Evolution of Tumor-Infiltrating Lymphocytes in Adoptive Cell Therapy for the Treatment of Solid Tumors

      Morgan Hulen , T., Chamberlain, C. A., Svane, Inge Marie & Met, Özcan, 2021, In: Immuno. 1, 3, p. 194-211

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Addition of interferon-alpha to a standard maturation cocktail induces CD38 up-regulation and increases dendritic cell function

      Trepiakas, R., Pedersen, Anders Elm, Met, Özcan & Svane, Inge Marie, 2009, In: Vaccine. 27, 16, p. 2213-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

      Kverneland, Anders Handrup, Pedersen, M., Wulff Westergaard, M. C., Nielsen, M., Borch, T. H., Olsen, L. R., Aasbjerg, G., Santegoets, S. J., van der Burg, S. H., Milne, K., Nelson, B. H., Met, Özcan, dqp123, dqp123 & Svane, Inge Marie, 2020, In: OncoTarget. 11, 22, p. 2092-2105 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients

      Ellebaek, E., Iversen, T. Z., Junker, N., Donia, M., Engell-Noerregaard, L., Met, Özcan, Hølmich, Lisbet Rosenkrantz, Andersen, R. S., Hadrup, S. R., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2012, In: Journal of Translational Medicine. 10, p. 169

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma

      Klausen, U., Grønne Dahlager Jørgensen, N., Grauslund, J. H., Munir Ahmad, S., Gang, Anne Ortved, Martinenaite, E., Weis-Banke, S. E., Breinholt, M. F., Novotny, G. W., Kjeldsen, J. W., Orebo Holmström, M., Pedersen, L. B., Poulsen, C. B., Hansen, P. B., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2021, In: OncoImmunology. 10, 1, 1975889.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Analysis of Survivin-Specific T Cells in Breast Cancer Patients Using Human DCs Engineered with Survivin mRNA

      Met, Özcan & Svane, Inge Marie, 2013, Synthetic Messenger RNA and Cell Metabolism Modulation. Vol. 969. p. 275-292 18 p. (Methods in Molecular Biology).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    8. Published

      Anti-PD-L1/PD-L2 therapeutic vaccination in untreated chronic lymphocytic leukemia patients with unmutated IgHV

      Klausen, U., Grauslund, J. H., Jørgensen, N. G. D., Ahmad, S. M., Jonassen, M., Weis-Banke, S. E., Martinenaite, E., Pedersen, L. B., Lisle, T. L., Gang, Anne Ortved, Enggaard, L., Hansen, M., Holmström, M. O., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2022, In: Frontiers in Oncology. 12, 1023015.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells

      Weis-Banke, S. E., Lisle, T. L., Perez Penco, Maria, Schina, A., Hübbe, M. L., Siersbæk, M., Holmström, M. O., Jørgensen, M. A., Svane, Inge Marie, Met, Özcan, Ødum, Niels, Madsen, Daniel Hargbøl, dqp123, dqp123, Grøntved, L. & Andersen, Mads Hald, 2022, In: Journal for ImmunoTherapy of Cancer. 10, 10, e005326.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Autocrine CCL19 blocks dendritic cell migration toward weak gradients of CCL21

      Hansen, M., Met, Özcan, Larsen, N. B., Rosenkilde, Mette, Andersen, Mads Hald, Svane, Inge Marie & Hjortø, Gertrud Malene, Sep 2016, In: Cytotherapy. 18, 9, p. 1187-1196

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Broadening the repertoire of melanoma-associated T-cell epitopes

      Frøsig, T. M., Lyngaa, R., Met, Özcan, Larsen, S. K., Donia, M., Svane, Inge Marie, Thor Straten, P. & Hadrup, S. R., May 2015, In: Cancer immunology, immunotherapy : CII. 64, 5, p. 609-20 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment

      Martinenaite, E., Munir Ahmad, S., Hansen, M., Met, Özcan, Westergaard, M. W., Larsen, S. K., Klausen, T. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, 2016, In: OncoImmunology. 5, 11, 10 p., e1238541.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      CTLA-4 blockade boosts the expansion of tumor-reactive CD8+ tumor-infiltrating lymphocytes in ovarian cancer

      Friese, C., Harbst, K., Borch, T. H., Westergaard, M. C. W., Pedersen, M., Kverneland, A., Jönsson, G., dqp123, dqp123, Svane, Inge Marie & Met, Özcan, 2020, In: Scientific Reports. 10, 1, 12 p., 3914.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine

      Gigoux, M., Holmström, M. O., Zappasodi, R., Park, J. J., Pourpe, S., Bozkus, C. C., Mangarin, L. M. B., Redmond, D., Verma, S., Schad, S., George, M. M., Venkatesh, D., Ghosh, A., Hoyos, D., Molvi, Z., Kamaz, B., Marneth, A. E., Duke, W., Leventhal, M. J., Jan, M. & 23 others, Ho, V. T., Hobbs, G. S., Knudsen, T. A., Skov, V., Kjær, L., Larsen, T. S., Hansen, D. L., Lindsley, R. C., Hasselbalch, Hans Carl, Grauslund, J. H., Lisle, T. L., Met, Özcan, Wilkinson, P., Greenbaum, B., Sepulveda, M. A., Chan, T., Rampal, R., Andersen, Mads Hald, Abdel-Wahab, O., Bhardwaj, N., Wolchok, J. D., Mullally, A. & Merghoub, T., 2022, In: Science Translational Medicine. 14, 649, eaba4380.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Cell culture plastics with immobilized interleukin-4 for monocyte differentiation

      Hansen, M., Hjortø, Gertrud Malene, Met, Özcan, Jakobsen, M. H., Svane, Inge Marie & Larsen, N. B., Feb 2011, In: Journal of Biomedical Materials Research. Part A. 96, 2, p. 372-83 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Cellular based cancer vaccines: type 1 polarization of dendritic cells

      Hansen, M., Met, Özcan, Svane, Inge Marie & Andersen, M. H., 2012, In: Current Medicinal Chemistry. 19, 25, p. 4239-46 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    17. Published

      Chemokine receptor engineering of T cells with CXCR2 improves homing towards subcutaneous human melanomas in xenograft mouse model

      Idorn, M., Skadborg, S. K., Kellermann, L., Halldórsdóttir, H. R., Holmen Olofsson, G., Met, Özcan & thor Straten, P., 2018, In: OncoImmunology. 7, 8, 10 p., e1450715.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Clinical advances and ongoing trials on mRNA vaccines for cancer treatment

      Lorentzen, C. L., Haanen, J. B., Met, Özcan & Svane, Inge Marie, 2022, In: The Lancet Oncology. 23, 10, p. e450-e458

      Research output: Contribution to journal › Review › Research › peer-review

    19. Published

      Clinical efficacy of T-cell therapy after short-term BRAF-inhibitor priming in patients with checkpoint inhibitor-resistant metastatic melanoma

      Borch, T. H., Harbst, K., Rana, A. H., Andersen, R., Martinenaite, E., Kongsted, P., Pedersen, M., Nielsen, M., Kjeldsen, J. W., Kverneland, Anders Handrup, Lauss, M., Hølmich, Lisbet Rosenkrantz, Hendel, Helle Westergren, Met, Özcan, Jönsson, G., dqp123, dqp123 & Svane, Inge Marie, 2021, In: Journal for ImmunoTherapy of Cancer. 9, 7, 15 p., e00270.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Comparison of alpha-Type-1 polarizing and standard dendritic cell cytokine cocktail for maturation of therapeutic monocyte-derived dendritic cell preparations from cancer patients.

      Trepiakas, R., Pedersen, Anders Elm, Met, Özcan, Hansen, M. H., Berntsen, A. & Svane, I. M., 2008, In: Vaccine. 26, 23, p. 2824-32 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy

      Hansen, M., Hjortø, Gertrud Malene, Donia, M., Met, Özcan, Larsen, N. B., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2013, In: Vaccine. 31, 4, p. 639-46 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Cytotoxic T cells isolated from healthy donors and cancer patients kill TGFβ-expressing cancer cells in a TGFβ-dependent manner

      Holmström, M. O., Mortensen, R. E. J., Pavlidis, A. M., Martinenaite, E., Weis-Banke, S. E., Aaboe-Jørgensen, M., Bendtsen, S. K., Met, Özcan, Pedersen, A. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, Feb 2021, In: Cellular and Molecular Immunology. 18, 2, p. 415-426 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Dendritic cell vaccination in combination with docetaxel for patients with metastatic castration-resistant prostate cancer: A randomized phase II study

      Kongsted, P., Borch, T. H., Ellebaek, E., Iversen, T. Z., Andersen, R., Met, Özcan, Hansen, M., Lindberg, H., Sengeløv, L. & Svane, Inge Marie, 1 Apr 2017, In: Cytotherapy. 19, 4, p. 500-513 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Efficient large volume electroporation of dendritic cells through micrometer scale manipulation of flow in a disposable polymer chip

      Selmeczi, D., Hansen, T. S., Met, Özcan, Svane, Inge Marie & Larsen, N. B., Apr 2011, In: Biomedical Microdevices. 13, 2, p. 383-92 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome

      Hu, T., Buus, T. B., Krejsgaard, T., Nansen, A., Lundholt, B. K., Spee, P., Fredholm, S., Petersen, D. L., Blümel, E., Gluud, M., Monteiro, M. N., Willerslev-Olsen, A., Andersen, M. H., Straten, P. T., Met, Ö., Stolearenco, V., Fogh, H., Gniadecki, R., Nastasi, C., Litman, T. & 3 others, Woetmann, Anders , Gjerdrum, Lise Mette Rahbek & Ødum, Niels, 2019, In: OncoTarget. 10, 47, p. 4894-4906 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 33971757