Judith Margarete Gottwein

Judith Margarete Gottwein

Associate Professor


  1. 2013
  2. Published

    Analysis of hepatitis C virus core/NS5A protein co-localization using novel cell culture systems expressing core-NS2 and NS5A of genotypes 1-7

    Galli, A., Scheel, Troels Kasper Høyer, Prentø, Jannick, Mikkelsen, L. S., Gottwein, Judith Margarete & Bukh, Jens, Oct 2013, In: The Journal of general virology. 94, Pt 10, p. 2221-35 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Viral hepatitis: Cell-culture-derived HCV--a promising vaccine antigen

    Gottwein, Judith Margarete & Bukh, Jens, Sep 2013, In: Nature Reviews. Gastroenterology & Hepatology. 10, 9, p. 508-9 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Efficient cell culture system for hepatitis C virus genotype 7a: Patent #: 8,506,969

    Gottwein, Judith Margarete, Scheel, T. K. H., Jensen, T. B. & Bukh, Jens, 13 Aug 2013, IPC No. A61K 39/12 (20060101); A61K 39/29 (20060101); C12Q 1/70 (20060101); C12N 15/00 (20060101); C12N 5/071 (20100101); C12N 1/20 (20060101), Patent No. WO2010/017819, 18 Feb 2010, Priority date 31 Jul 2009, Priority No. PCT/DK2009/050193

    Research output: Patent

  5. Published

    Adaptive mutations allow establishment of JFH1-based cell culture systems for hepatitis C virus genotype 4A: Patent #: 8,454,974

    Scheel, T. K. H., Gottwein, Judith Margarete, Eugen-Olsen, J. & Bukh, Jens, 4 Jun 2013, IPC No. A61K 39/29 (20060101); C07H 21/00 (20060101); C12N 15/06 (20060101); C12N 7/02 (20060101); C12Q 1/02 (20060101), Patent No. WO2008/125119, 23 Oct 2008, Priority date 11 Apr 2008, Priority No. PCT/DK2008/050085

    Research output: Patent

  6. Published

    Combination treatment with hepatitis C virus protease and NS5A inhibitors is effective against recombinant genotype 1a, 2a, and 3a viruses

    Gottwein, Judith Margarete, Jensen, S. B., Li, Y., Ghanem, L., Scheel, Troels Kasper Høyer, Serre, S. B. N., Mikkelsen, L. & Bukh, Jens, Mar 2013, In: Antimicrobial Agents and Chemotherapy. 57, 3, p. 1291-303 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Productive homologous and non-homologous recombination of hepatitis C virus in cell culture

    Scheel, Troels Kasper Høyer, Galli, A., Li, Y., Mikkelsen, L. S., Gottwein, Judith Margarete & Bukh, Jens, Mar 2013, In: P L o S Pathogens. 9, 3, p. 1-12 13 p., e1003228.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Neutralization resistance of hepatitis C virus can be overcome by recombinant human monoclonal antibodies

    Pedersen, J. L., Carlsen, T. H. R., Prentø, Jannick, Ramirez, S., Jensen, T. B., Forns, X., Alter, H., Foung, S. K. H., Law, M., Gottwein, Judith Margarete, Weis, Nina & Bukh, Jens, 2013, In: Hepatology. 58, 5, p. 1587-1597 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2012
  10. Published

    Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system

    Li, Y., Ramirez, S., Jensen, S. B., Purcell, R. H., Gottwein, Judith Margarete & Bukh, Jens, 27 Nov 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 48, p. 19757-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Efficient replication of genotype 3a and 4a hepatitis C virus replicons in human hepatoma cells

    Saeed, M., Scheel, Troels Kasper Høyer, Gottwein, Judith Margarete, Marukian, S., Dustin, L. B., Bukh, Jens & Rice, C. M., Oct 2012, In: Antimicrobial Agents and Chemotherapy. 56, 10, p. 5365-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Analysis of functional differences between hepatitis C virus NS5A of genotypes 1-7 in infectious cell culture systems

    Scheel, Troels Kasper Høyer, Prentø, Jannick, Carlsen, T. H. R., Mikkelsen, L. S., Gottwein, Judith Margarete & Bukh, Jens, 2012, In: P L o S Pathogens. 8, 5, p. 1-16 17 p., e1002696.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 40928930