Judith Margarete Gottwein

Judith Margarete Gottwein

Associate Professor

ORCID: 0000-0003-2805-0256

Publication year:
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31 - 40 out of 70Page size: 10
  1. 2017
  2. Published

    Efficient hepatitis c virus genotype 1b core-NS5A recombinants permit efficacy testing of protease and NS5A inhibitors

    Pham, Long, Ramirez Almeida, Santseharay, Carlsen, T. H. R., Li, Y., Gottwein, Judith Margarete & Bukh, Jens, 2017, In: Antimicrobial Agents and Chemotherapy. 61, 6, 19 p., e00037-17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2016
  4. Published

    Robust HCV Genotype 3a Infectious Cell Culture System Permits Identification of Escape Variants With Resistance to Sofosbuvir

    Ramirez Almeida, Santseharay, Mikkelsen, L. S., Gottwein, Judith Margarete & Bukh, Jens, Nov 2016, In: Gastroenterology. 151, 5, p. 973-985.e2

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Hepatitis C Virus Genotype 1 to 6 Protease Inhibitor Escape Variants: In Vitro Selection, Fitness, and Resistance Patterns in the Context of the Infectious Viral Life Cycle.

    Serre, S., Jensen, S., Ghanem, L., Humes, D., Ramirez, S., Li, Y., Krarup, H., Bukh, Jens & Gottwein, Judith Margarete, Jun 2016, In: Antimicrobial Agents and Chemotherapy. 60, 6, p. 3563-3578 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2015
  7. Published

    Substitutions at NS3 Residue 155, 156, or 168 of Hepatitis C Virus Genotypes 2 to 6 Induce Complex Patterns of Protease Inhibitor Resistance

    Jensen, S. B., Serre, S. B. N., Humes, D. G., Ramirez Almeida, Santseharay, Li, Y., Bukh, Jens & Gottwein, Judith Margarete, Dec 2015, In: Antimicrobial Agents and Chemotherapy. 59, 12, p. 7426-7436 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Adaptive Mutations Enhance Assembly and Cell-to-Cell Transmission of a High-Titer Hepatitis C Virus Genotype 5a Core-NS2 JFH1-Based Recombinant

    Mathiesen, C. K., Prentø, Jannick, Meredith, L. W., Jensen, T. B., Krarup, H., McKeating, J. A., Gottwein, Judith Margarete & Bukh, Jens, Aug 2015, In: Journal of Virology. 89, 15, p. 7758-7775 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Cell culture system of a hepatitis C genotype 3a and 2a chimera: Patent #: 8,945,584

    Gottwein, Judith Margarete, Scheel, T. K. H., Eugen-Olsen, J. & Bukh, Jens, 3 Feb 2015, IPC No. A61K 39/29 (20060101); C12N 15/06 (20060101); C12Q 1/02 (20060101); C07H 21/00 (20060101); C12N 7/02 (20060101); A61K 39/12 (20060101), Patent No. WO2008/125117, 23 Oct 2008, Priority date 11 Apr 2008, Priority No. PCT/DK2008/050083

    Research output: Patent

  10. Published

    Infectious hepatitis C viruses of genotype 3A and 4A and uses thereof: Patent #: 8,946,398

    Gottwein, Judith Margarete, Scheel, T. K. H., Purcell, R. E. & Bukh, Jens, 3 Feb 2015, IPC No. C07H 21/04 (20060101); C07H 21/02 (20060101), Patent No. WO2011/038737, 26 Jul 2012, Priority date 16 Sep 2010, Priority No. PCT/DK2010/050236

    Research output: Patent

  11. Published

    High Reproducibility of ELISPOT Counts from Nine Different Laboratories.

    Sundararaman, S., Karulin, A., Ansari, T., BenHamouda, N., Gottwein, Judith Margarete, Laxmanan, S., Levine, S., Loffredo, J., McArdle, S., Neudoerfl, C., Roen, D., Silina, K., Welch, M. & Lehmann, P., 2015, In: Cells.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2014
  13. Published

    Infectious genotype 1a, 1b, 2a, 2b, 3a, 5a, 6a and 7a hepatitis C virus lacking the hypervariable region 1 (HVR1): Patent #: 8,846,891

    Prentø, Jannick, Gottwein, Judith Margarete, Scheel, T. K. H., Bukh, Jens & Jensen, T. B., 30 Sep 2014, IPC No. C07H 21/04 (20060101); C07H 21/02 (20060101), Patent No. WO2010/022727, 4 Mar 2010, Priority date 7 Aug 2009, Priority No. PCT/DK2009/050197

    Research output: Patent

  14. Published

    Hepatitis C virus expressing reporter tagged NS5A protein: Patent #: 8,772,022

    Gottwein, Judith Margarete, Scheel, T. K. H., Bukh, Jens, Prentø, Jannick & Jensen, T. B., 8 Jul 2014, IPC No. C12N 15/00 (20060101); C12N 5/00 (20060101); C12N 7/00 (20060101); C12N 15/64 (20060101); A61K 39/29 (20060101); C12N 7/01 (20060101), Patent No. WO2010/037403, 8 Apr 2010, Priority date 5 Oct 2009, Priority No. PCT/DK2009/050263

    Research output: Patent

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