Thomas Litman

Thomas Litman

Professor

Member of:

    ORCID: 0000-0002-6068-901X

    Introductory remarks on publicationslist

    For reprints, just write me, or download directly, if available.


    Publication year:
    All
    101 - 141 out of 141Page size: 50
    1. 2002
    2. Published

      Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

      Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 5 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 3, p. 1683-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells

      Poulsen, K. A., Litman, Thomas, Eriksen, J., Mollerup, J. & Lambert, Ian Henry, 2002, In: Amino Acids. 22, p. 333-350

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Functional analysis of candidate ABC transporters proteins for sitosterol transport

      Albrecht, C., Elliott, J. I., Sardini, A., Litman, Thomas, Stieger, B., Meier, P. J. & Higgins, C. F., 2002, In: Biochem. Biophys. Acta. 133-142, p. 1567

      Research output: Contribution to journal › Journal article › Research

    5. Published

      Generation of an activating ZN(2+) switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

      Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 2002, In: Proceedings of the National Academy of Science of the United States of America. vol. 99(3), p. 1683-8

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Impact of BCRP/MXR, MRP1 and MDR1/P-Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells

      Stein, U., Lage, H., Jordan, A. D., Walther, W., Bates, S. E., Litman, Thomas, Hohenberger, P. & Dietel, M., 2002, In: International Journal of Cancer. 97, p. 751-760

      Research output: Contribution to journal › Journal article › Research

    7. Published

      Measurement of cell volume changes by fluorescence self-quenching

      Hamann, Steffen, Kiilgaard, J. F., Litman, Thomas, Alvarez-Leefmans, F. J., Winther, B. R. & Zeuthen, Thomas, 2002, In: Journal of Fluorescence. 12, 2, p. 139-145 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. 2001
    9. Published

      The role of half-transporters in multidrug resistance

      Bates, S. E., Robey, R., Miyake, K., Rao, K., Ross, D. D. & Litman, Thomas, Dec 2001, In: Journal of Bioenergetics and Biomembranes. 33, 6, p. 503-11 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Expression of P-glycoprotein and multidrug resistance associated protein in Ehrlich ascites tumor cells after fractionated irradiation

      Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas & Skovsgaard, T., 15 Nov 2001, In: International Journal of Radiation Oncology, Biology, Physics. 51, 4, p. 1050-7 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells

      Honjo, Y., Hrycyna, C. A., Yan, Q. W., Medina-Pérez, W. Y., Robey, R. W., van de Laar, A., Litman, Thomas, Dean, M. & Bates, S. E., 15 Sep 2001, In: Cancer Research. 61, 18, p. 6635-6639 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

      Ozvegy, C., Litman, Thomas, Szakács, G., Nagy, Z., Bates, S., Váradi, A. & Sarkadi, B., 6 Jul 2001, In: Biochemical and Biophysical Research Communications. 285, 1, p. 111-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)

      Robey, R. W., Honjo, Y., van de Laar, A., Miyake, K., Regis, J. T., Litman, Thomas & Bates, S. E., 6 Jun 2001, In: BBA General Subjects. 1512, 2, p. 171-82 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance

      Litman, Thomas, Druley, T. E., Stein, W. D. & Bates, S. E., Jun 2001, In: Cellular and molecular life sciences : CMLS. 58, 7, p. 931-59 29 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Cellular and biophysical evidence for interactions between adenosine triphosphate and P-glycoprotein substrates: functional implications for adenosine triphosphate/drug cotransport in P-glycoprotein overexpressing tumor cells and in P-glycoprotein low-level expressing erythrocytes

      Abraham, E. H., Shrivastav, B., Salikhova, A. Y., Sterling, K. M., Johnston, N., Guidotti, G., Scala, S., Litman, Thomas, Chan, K. C., Arceci, R. J., Steiglitz, K., Herscher, L. & Okunieff, P., 19 May 2001, In: Blood Cells, Molecules and Diseases. 27, 1, p. 181-200 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells

      Robey, R. W., Medina-Pérez, W. Y., Nishiyama, K., Lahusen, T., Miyake, K., Litman, Thomas, Senderowicz, A. M., Ross, D. D. & Bates, S. E., Jan 2001, In: Clinical Cancer Research. 7, 1, p. 145-52 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      A functional assay for detection of the mitoxantrone resistance protein MXR (ABCG2)

      Robey, R. W., Miyake, K., van de Laar, A., Honjo, Y., Regis, J. T., Litman, Thomas & Bates, S. E., 2001, In: BBA General Subjects. 1512, p. 171-182

      Research output: Contribution to journal › Journal article › Research

    18. Published

      Cellular and biophysical evidence for interactions between Adenosine Triphosphate and P-Glycoprotein substrates: Functional implications for Adenosine Triphosphate/Drug Cotransport in P-Glycoprotein overexpressing tumor cells and in P-Glycoprotein low-level expressing erythrocytes

      Abraham, E. H., Shrivastav, B., Salikova, A. Y., Sterling, K. M., Johnston, N., Guidotti, G., Scala, S., Litman, Thomas, Chan, K. C., Arceci, R. J., Steiglitz, K., Herscher, L. & Okunieff, P., 2001, In: Blood Cells, Molecules and Diseases. 27, p. 181-200

      Research output: Contribution to journal › Journal article › Research

    19. Published

      Expression of P-glycoprotein and multidrug resistance associated protein in Ehrlich ascites tumor cells after fractionated irradiation

      Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas & Skovsgaard, T., 2001, In: Int J Radiat Oncol Biol Phys. 51, p. 1050-1057

      Research output: Contribution to journal › Journal article › Research

    20. Published

      From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance

      Litman, Thomas, Druley, T. E., Stein, W. D. & Bates, S. E., 2001, In: Cell Mol Life Sci.. 931-959, p. 58

      Research output: Contribution to journal › Journal article › Research

    21. Published

      Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

      Ozvegy, C., Litman, Thomas, Szakacs, G., Nagy, Z., Bates, S., Varadi, A. & Sarkadi, B., 2001, In: Biochem. Biophys. Res. Commun.. 285, p. 111-117

      Research output: Contribution to journal › Journal article › Research

    22. Published

      Overexpression of the mitoxantrone resistance ATP binding cassette half-transporter, ABCG2 (BCRP/MXR/ABCP), in flavopiridol-resistant human breast cancer cells

      Robey, R. W., Medina-Perez, W. Y., Nishiyama, K., Litman, Thomas, Miyake, K., Senderowicz, A. M. & Bates, S., 2001, In: Clinical Cancer Research. 7, p. 145-152

      Research output: Contribution to journal › Journal article › Research

    23. Published

      The role of half-transporters in multidrug resistance

      Bates, S. E., Robey, R., Miyake, K., Rao, K., Ross, D. D. & Litman, Thomas, 2001, In: J Bioenerg Biomembr. 503-511, p. 33

      Research output: Contribution to journal › Journal article › Research

    24. 2000
    25. Published

      New ABC transporters in multi-drug resistance

      Bates, S. E., Robey, R., Knutsen, T., Honjo, Y., Litman, Thomas & Dean, M., 1 Oct 2000, In: Expert Opinion On Therapeutic Targets. 4, 5, p. 561-580 20 p.

      Research output: Contribution to journal › Review › Research › peer-review

    26. Published

      Characterisation of multidrug-resistant Ehrlich ascites tumour cells selected in vivo for resistance to etoposide

      Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas, Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 353-61 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone

      Nielsen, D., Eriksen, J., Maare, C., Litman, Thomas, Kjaersgaard, E., Plesner, T., Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 363-70 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

      Litman, Thomas, Brangi, M., Hudson, E., Fetsch, P., Abati, A., Ross, D. D., Miyake, K., Resau, J. H. & Bates, S. E., Jun 2000, In: Journal of Cell Science. 113 ( Pt 11), p. 2011-21 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane

      Rocchi, E., Khodjakov, A., Volk, E. L., Yang, C. H., Litman, Thomas, Bates, S. E. & Schneider, E., 29 Apr 2000, In: Biochemical and Biophysical Research Communications. 271, 1, p. 42-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone

      Nielsen, D., Eriksen, J., Maare, C., Litman, Thomas, Kjaersgaard, E., Plesner, T., Friche, E. & Skovsgaard, T., 2000, In: Biochem Pharmacol.. 363-370, p. 60

      Research output: Contribution to journal › Journal article › Research

    31. 1999
    32. Published

      Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

      Brangi, M., Litman, Thomas, Ciotti, M., Nishiyama, K., Kohlhagen, G., Takimoto, C., Robey, R., Pommier, Y., Fojo, T. & Bates, S. E., 1 Dec 1999, In: Cancer Research. 59, 23, p. 5938-46 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR

      de Bruin, M., Miyake, K., Litman, Thomas, Robey, R. & Bates, S. E., 15 Nov 1999, In: Cancer Letters. 146, 2, p. 117-26 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833

      Robey, R., Bakke, S., Stein, W., Meadows, B., Litman, Thomas, Patil, S., Smith, T., Fojo, T. & Bates, S., 1 Jan 1999, In: Blood. 93, 1, p. 306-14 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

      Miyake, K., Mickley, L., Litman, Thomas, Zhan, Z., Robey, R., Cristensen, B., Brangi, M., Greenberger, L., Dean, M., Fojo, T. & Bates, S. E., 1 Jan 1999, In: Cancer Research. 59, 1, p. 8-13 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. 1998
    37. Published

      pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells

      Litman, Thomas, Pedersen, Stine Helene Falsig, Kramhøft, B., Skovsgaard, T. & Hoffmann, E. K., 1998, In: Cell. Physiol. Biochem.. 8, p. 138-150

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells

      Litman, Thomas, Pedersen, S. F., Kramhøft, B., Skovsgaard, T. & Hoffmann, E. K., 1998, In: Cellular Physiology and Biochemistry. 8, 3, p. 138-50 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. 1997
    40. Published

      The multidrug resistant phenotype - A comparative study

      Litman, Thomas, 1 Dec 1997, In: Ugeskrift for Laeger. 159, 6, p. 771-772 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      ATPase activity of P-glycoprotein related to emergence of drug resistance in Ehrlich ascites tumor cell lines

      Litman, Thomas, Nielsen, D., Skovsgaard, T., Zeuthen, Thomas & Stein, W. D., 1997, In: BBA General Subjects. 1361, 2, p. 147-158

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity

      Litman, Thomas, Zeuthen, Thomas, Skovsgaard, T. & Stein, W. D., 1997, In: BBA General Subjects. vol. 1361, p. 169-176

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Drug accumulation in the presence of the multidrug resistance pump: dissociation between verapamil accumulation and the action of P-glycoprotein

      Ayesh, S., Litman, Thomas & Stein, W. D., 1997, In: Receptors and Channels. 5, 3-4, p. 175-83 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Structure-activity relationships of P-glycoprotein interacting drugs: kinetic characterization of their effects on ATPase activity

      Litman, Thomas, Zeuthen, Thomas, Skovsgaard, T. & Stein, W. D., 1997, In: BBA General Subjects. 1361, 2, p. 159-168

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Water transport by the Na+/glucose cotransporter under isotonic conditions

      Zeuthen, Thomas, Meinild, A. K., Klaerke, D. A., Loo, D. D., Wright, E. M., Belhage, B. & Litman, Thomas, 1997, In: Biology of the Cell. 89, 5-6, p. 307-12 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Water transport by the Na+/glucose cotransporter under isotonic conditions

      Zeuthen, T., Meinild, A. K., Klærke, D., Loo, D. D. F., Wright, E. M., Belhage, B. & Litman, Thomas, 1997, In: Biology of the Cell. Vol. 89, p. 307-312

      Research output: Contribution to journal › Journal article › Research

    47. 1995
    48. Published

      Lipid composition of sensitive and multidrug resistant Ehrlich ascites tumour cells

      Litman, Thomas, Nielsen, D., Skovsgaard, T. & Bukhave, K., 1995, In: Cellular Pharmacology. Vol 2, p. 9-14

      Research output: Contribution to journal › Journal article › Research

    Previous 1 2 3 Next

    ID: 33298538