Kenn Holmbeck

Kenn Holmbeck

Associate Professor

ORCID: 0000-0002-4472-3257

Publication year:
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1 - 54 out of 54Page size: 500
  1. 2023
  2. Published

    An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals

    Offersgaard, Anna Falden, Duarte Hernandez, Carlos Rene, Feng, S., Marichal-Gallardo, P., Holmbeck, Kenn, Pihl, A. F., Fernandez-Antunez, C., Alzua, G. P., Hartmann, Katrine Top, Pham, Long, Zhou, Y., Gammeltoft, Karen Anbro, Fahnøe, Ulrik, Schneider, Uffe Vest, Pedersen, Gabriel Kristian, Jensen, Henrik Elvang, Christensen, Jan Pravsgaard, Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: iScience. 26, 2, 105949.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Full-length sequence analysis of hepatitis C virus genotype 3b strains and development of an in vivo infectious 3b cDNA clone

    Bajpai, P. S., Collignon, Laura Maria F, Sølund, C., Madsen, L. W., Christensen, P. B., Øvrehus, A., Weis, Nina, Holmbeck, Kenn, Fahnøe, Ulrik & Bukh, Jens, 2023, In: Journal of Virology. 97, 12, 23 p., 00925.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide

    Sherwood, A. V., Rivera-Rangel, L. R., Ryberg, L. A., Larsen, H. S., Anker, K. M., Costa, R., Vågbø, C. B., Jakljevič, E., Pham, L. V., Fernandez-Antunez, C., Indrisiunaite, G., Podolska-Charlery, A., Grothen, J. E. R., Langvad, N. W., Fossat, N., Offersgaard, A., Al-Chaer, A., Nielsen, L., Kuśnierczyk, A., Sølund, C. & 8 others, Weis, Nina, Gottwein, Judith Margarete, Holmbeck, Kenn, Bottaro, S., Ramirez Almeida, Santseharay, Bukh, Jens, Scheel, Troels Kasper Høyer & Vinther, Jeppe, 2023, In: Nature. 619, p. 811-818

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Molecular Determinants of Mouse Adaptation of Rat Hepacivirus

    Wolfisberg, R., Holmbeck, Kenn, Billerbeck, E., Thorselius, Caroline Eva, Batista, M. N., Fahnøe, Ulrik, Lundsgaard, Emma Alberte, Kennedy, Matthew James, Nielsen, L., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Journal of Virology. 97, 4, 17 p., e0181222.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2022
  7. Published

    Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals

    Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Holmbeck, K., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P. & 5 others, Ramirez Almeida, Santseharay, Reichl, U., Genzel, Y., Bukh, J. & Gottwein, Judith Margarete, 6 Jul 2022.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  8. Published

    Neutralization and receptor use of infectious culture–derived rat hepacivirus as a model for HCV

    Wolfisberg, R., Thorselius, Caroline Eva, Salinas, E., Elrod, E., Trivedi, S., Nielsen, L., Fahnøe, Ulrik, Kapoor, A., Grakoui, A., Rice, C. M., Bukh, Jens, Holmbeck, Kenn & Scheel, Troels Kasper Høyer, 2022, In: Hepatology. 76, 5, p. 1506-1519

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Novel HCV Genotype 4d Infectious Systems and Assessment of Direct-Acting Antivirals and Antibody Neutralization

    Pham, Long, Velázquez-Moctezuma, R., Fahnøe, Ulrik, Collignon, Laura Maria F, Bajpai, P., Sølund, C., Weis, Nina, Holmbeck, Kenn, Prentø, Jannick & Bukh, Jens, 2022, In: Viruses. 14, 11, 2527.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2019
  11. Published

    Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells

    Wolfisberg, R., Holmbeck, Kenn, Nielsen, L., Kapoor, A., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2019, In: Journal of Virology. 93, 19, 19 p., e00733-19.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2018

  13. MT3-MMP Promotes Excitatory Synapse Formation by Promoting Nogo-66 Receptor Ectodomain Shedding

    Sanz, R. L., Ferraro, G. B., Kacervosky, J., Salesse, C., Gowing, E., Hua, L., Rambaldi, I., Beaubien, F., Holmbeck, Kenn, Cloutier, J. F., Lévesque, M., Murai, K. & Fournier, A. E., 2018, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 38, 3, p. 518-529 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2017

  15. Btbd7 is essential for region-specific epithelial cell dynamics and branching morphogenesis in vivo

    Daley, W. P., Matsumoto, K., Doyle, A. D., Wang, S., DuChez, B. J., Holmbeck, Kenn & Yamada, K. M., 2017, In: Development (Cambridge). 144, 12, p. 2200-2211 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia

    Mayer, B., Németh, K., Krepuska, M., Myneni, V. D., Maric, D., Tisdale, J. F., Hsieh, M. M., Uchida, N., Lee, H-J., Nemeth, M. J., Holmbeck, K., Noguchi, C. T., Rogers, H., Dey, S., Hansen, A., Hong, J., Chow, I., Key, S., Szalayova, I., Pagani, J. & 6 others, Markó, K., McClain-Caldwell, I., Vitale-Cross, L., Young, W. S., Brownstein, M. J. & Mezey, É., 2017, In: Science Translational Medicine. 9, 418

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2016

  18. Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream

    Langenfurth, A., Gu, S., Bautze, V., Zhang, C., Neumann, J. E., Schüller, U., Stock, K., Wolf, S. A., Maier, A., Mastrella, G., Pak, A., Cheng, H., Kälin, R. E., Holmbeck, Kenn, Strotmann, J., Kettenmann, H. & Glass, R., 30 Aug 2016, In: Scientific Reports. 6, 32203.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo

    Motley, M. P., Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Spencer, D. E., Szabo, R., Holmbeck, Kenn, Flick, M. J., Lawrence, D. A., Castellino, F. J., Weigert, R. & Bugge, T. H., 2016, In: Blood. 127, 9, p. 1085-1096 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Multiple essential MT1-MMP functions in tooth root formation, dentinogenesis, and tooth eruption

    Xu, H., Snider, T. N., Wimer, H. F., Yamada, S. S., Yang, T., Holmbeck, Kenn & Foster, B. L., 2016, In: Matrix Biology. 52-54, p. 266-283 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2015

  22. Mice Deficient in AKAP13 (BRX) Are Osteoporotic and Have Impaired Osteogenesis

    Koide, H., Holmbeck, Kenn, Lui, J. C., Guo, X. C., Driggers, P., Chu, T., Tatsuno, I., Quaglieri, C., Kino, T., Baron, J., Young, M. F., Robey, P. G. & Segars, J. H., Oct 2015, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30, 10, p. 1887-95 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Osteoblast-specific expression of the fibrous dysplasia (FD)-causing mutation Gsα(R201C) produces a high bone mass phenotype but does not reproduce FD in the mouse

    Remoli, C., Michienzi, S., Sacchetti, B., Consiglio, A. D., Cersosimo, S., Spica, E., Robey, P. G., Holmbeck, Kenn, Cumano, A., Boyde, A., Davis, G., Saggio, I., Riminucci, M. & Bianco, P., Jun 2015, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30, 6, p. 1030-43 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling

    Maeda, A., Ono, M., Holmbeck, Kenn, Li, L., Kilts, T. M., Kram, V., Noonan, M. L., Yoshioka, Y., McNerny, E. M. B., Tantillo, M. A., Kohn, D. H., Lyons, K. M., Robey, P. G. & Young, M. F., 2015, In: The Journal of Biological Chemistry. 290, 22, p. 14004-14018 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2014

  26. Biglycan modulates angiogenesis and bone formation during fracture healing

    Berendsen, A. D., Pinnow, E. L., Maeda, A., Brown, A. C., McCartney-Francis, N., Kram, V., Owens, R. T., Robey, P. G., Holmbeck, Kenn, de Castro, L. F., Kilts, T. M. & Young, M. F., Apr 2014, In: Matrix Biology. 35, p. 223-31 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Constitutive expression of Gsα(R201C) in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history

    Saggio, I., Remoli, C., Spica, E., Cersosimo, S., Sacchetti, B., Robey, P. G., Holmbeck, Kenn, Cumano, A., Boyde, A., Bianco, P. & Riminucci, M., 2014, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 29, 11, p. 2357-68 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. 2010
  29. Published

    Membrane-type MMPs are indispensable for placental labyrinth formation and development

    Szabova, L., Son, M., Shi, J., Sramko, M., Yamada, S. S., Swaim, W. D., Zerfas, P., Kahan, S. & Holmbeck, Kenn, 16 Dec 2010, In: Blood. 116, 25, p. 5752-61 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Carcinomas contain a matrix metalloproteinase-resistant isoform of type I collagen exerting selective support to invasion

    Makareeva, E., Han, S., Vera, J. C., Sackett, D. L., Holmbeck, Kenn, Phillips, C. L., Visse, R., Nagase, H. & Leikin, S., 1 Jun 2010, In: Cancer Research. 70, 11, p. 4366-74 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2009
  32. Published

    MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis

    Rebustini, I. T., Myers, C., Lassiter, K. S., Surmak, A., Szabova, L., Holmbeck, Kenn, Pedchenko, V., Hudson, B. G. & Hoffman, M. P., Oct 2009, In: Developmental Cell. 17, 4, p. 482-93 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion

    Markovic, D. S., Vinnakota, K., Chirasani, S., Synowitz, M., Raguet, H., Stock, K., Sliwa, M., Lehmann, S., Kälin, R., van Rooijen, N., Holmbeck, Kenn, Heppner, F. L., Kiwit, J., Matyash, V., Lehnardt, S., Kaminska, B., Glass, R. & Kettenmann, H., 28 Jul 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 30, p. 12530-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. 2008
  35. Published

    MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease

    Szabova, L., Chrysovergis, K., Yamada, S. S. & Holmbeck, Kenn, 22 May 2008, In: Oncogene. 27, 23, p. 3274-81 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Development of craniofacial structures in transgenic mice with constitutively active PTH/PTHrP receptor

    Tsutsui, T. W., Riminucci, M., Holmbeck, Kenn, Bianco, P. & Robey, P. G., Feb 2008, In: Bone. 42, 2, p. 321-31 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Membrane-type MMPs enable extracellular matrix permissiveness and mesenchymal cell proliferation during embryogenesis

    Shi, J., Son, M., Yamada, S., Szabova, L., Kahan, S., Chrysovergis, K., Wolf, L., Surmak, A. & Holmbeck, Kenn, 1 Jan 2008, In: Developmental Biology. 313, 1, p. 196-209 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells

    Ingvarsen, S. Z., Madsen, D. H., Hillig, T., Lund, L. R., Holmbeck, Kenn, Behrendt, Niels & Engelholm, L. H., 2008, In: Biological Chemistry. 389, 7, p. 943-953 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2007

  40. Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

    Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, Henrik, Høyer-Hansen, G., Holmbeck, Kenn, Bugge, T. H. & Behrendt, Niels, 14 Sep 2007, In: The Journal of Biological Chemistry. 282, 37, p. 27037-45 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Complementary roles of intracellular and pericellular collagen degradation pathways in vivo

    Wagenaar-Miller, R. A., Engelholm, Lars Henning, Gavard, J., Yamada, S. S., Gutkind, J. S., Behrendt, Niels, Bugge, T. H. & Holmbeck, Kenn, Sep 2007, In: Molecular and Cellular Biology. 27, 18, p. 6309-22 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Membrane type 1 matrix metalloproteinase is necessary for distal airway epithelial repair and keratinocyte growth factor receptor expression after acute injury

    Atkinson, J. J., Toennies, H. M., Holmbeck, Kenn & Senior, R. M., Sep 2007, In: American Journal of Physiology: Lung Cellular and Molecular Physiology. 293, 3, p. L600-10

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    GNAS transcripts in skeletal progenitors: evidence for random asymmetric allelic expression of Gs alpha

    Michienzi, S., Cherman, N., Holmbeck, Kenn, Funari, A., Collins, M. T., Bianco, P., Robey, P. G. & Riminucci, M., 15 Aug 2007, In: Human Molecular Genetics. 16, 16, p. 1921-30 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    MT1-MMP controls tumor-induced angiogenesis through the release of semaphorin 4D

    Basile, J. R., Holmbeck, Kenn, Bugge, T. H. & Gutkind, J. S., 2 Mar 2007, In: The Journal of Biological Chemistry. 282, 9, p. 6899-905 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. 2006
  46. Published

    Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo

    Zhang, W., Matrisian, L. M., Holmbeck, Kenn, Vick, C. C. & Rosenthal, E. L., 6 Mar 2006, In: BMC Cancer. 6, p. 52

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Aspects of extracellular matrix remodeling in development and disease

    Holmbeck, Kenn & Szabova, L., Mar 2006, In: Birth Defects Research. Part C: Embryo Today Reviews (Print). 78, 1, p. 11-23 13 p.

    Research output: Contribution to journal › Review › Research

  48. 2005
  49. Published

    Expression pattern of four membrane-type matrix metalloproteinases in the normal and diseased mouse mammary gland

    Szabova, L., Yamada, S. S., Birkedal-Hansen, H. & Holmbeck, Kenn, Oct 2005, In: Journal of Cellular Physiology. 205, 1, p. 123-32 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells

    Filippov, S., Koenig, G. C., Chun, T., Hotary, K. B., Ota, I., Bugge, T. H., Roberts, J. D., Fay, W. P., Birkedal-Hansen, H., Holmbeck, Kenn, Sabeh, F., Allen, E. D. & Weiss, S. J., 5 Sep 2005, In: The Journal of Experimental Medicine. 202, 5, p. 663-71 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature

    Lehti, K., Allen, E., Birkedal-Hansen, H., Holmbeck, Kenn, Miyake, Y., Chun, T. & Weiss, S. J., 15 Apr 2005, In: Genes & Development. 19, 8, p. 979-91 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Membrane-type 1 matrix metalloproteinase is required for normal alveolar development

    Atkinson, J. J., Holmbeck, Kenn, Yamada, S., Birkedal-Hansen, H., Parks, W. C. & Senior, R. M., Apr 2005, In: Developmental Dynamics. 232, 4, p. 1079-90 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    The metalloproteinase MT1-MMP is required for normal development and maintenance of osteocyte processes in bone

    Holmbeck, Kenn, Bianco, P., Pidoux, I., Inoue, S., Billinghurst, R. C., Wu, W., Chrysovergis, K., Yamada, S., Birkedal-Hansen, H. & Poole, A. R., 1 Jan 2005, In: Journal of Cell Science. 118, Pt 1, p. 147-56 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Collagenase in cranial morphogenesis

    Holmbeck, Kenn, 2005, In: Cells, Tissues, Organs. 181, 3-4, p. 154-65 12 p.

    Research output: Contribution to journal › Review › Research

  55. 2004
  56. Published

    MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix

    Chun, T., Sabeh, F., Ota, I., Murphy, H., McDonagh, K. T., Holmbeck, Kenn, Birkedal-Hansen, H., Allen, E. D. & Weiss, S. J., 22 Nov 2004, In: The Journal of Cell Biology. 167, 4, p. 757-67 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP

    Sabeh, F., Ota, I., Holmbeck, Kenn, Birkedal-Hansen, H., Soloway, P., Balbin, M., Lopez-Otin, C., Shapiro, S., Inada, M., Krane, S., Allen, E., Chung, D. & Weiss, S. J., 22 Nov 2004, In: The Journal of Cell Biology. 167, 4, p. 769-81 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    MT1-MMP: a tethered collagenase

    Holmbeck, Kenn, Bianco, P., Yamada, S. & Birkedal-Hansen, H., Jul 2004, In: Journal of Cellular Physiology. 200, 1, p. 11-9 9 p.

    Research output: Contribution to journal › Review › Research

  59. 2003
  60. Published

    MT1-MMP-dependent, apoptotic remodeling of unmineralized cartilage: a critical process in skeletal growth

    Holmbeck, Kenn, Bianco, P., Chrysovergis, K., Yamada, S. & Birkedal-Hansen, H., 10 Nov 2003, In: The Journal of Cell Biology. 163, 3, p. 661-71 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    MT1-mmp: a collagenase essential for tumor cell invasive growth

    Holmbeck, Kenn, Bianco, P. & Birkedal-Hansen, H., Aug 2003, In: Cancer Cell. 4, 2, p. 83-4 2 p.

    Research output: Contribution to journal › Journal article › Research

  62. Published

    uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

    Engelholm, Lars Henning, List, K., Netzel-Arnett, S., Cukierman, E., Mitola, D. J., Aaronson, H., Kjøller, L., Larsen, J. K., Yamada, K. M., Strickland, D. K., Holmbeck, Kenn, Danø, K., Birkedal-Hansen, H., Behrendt, Niels & Bugge, T. H., 31 Mar 2003, In: Journal of Cell Biology. 160, 7, p. 1009-15 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Inhibition of molar eruption and root elongation in MT1-MMP-deficient mice

    Beertsen, W., Holmbeck, Kenn, Niehof, A., Bianco, P., Chrysovergis, K., Birkedal-Hansen, H. & Everts, V., 2003, In: Connective Tissue Research. 44 Suppl 1, p. 298-9 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. 2002
  65. Published

    On the role of MT1-MMP, a matrix metalloproteinase essential to collagen remodeling, in murine molar eruption and root growth

    Beertsen, W., Holmbeck, Kenn, Niehof, A., Bianco, P., Chrysovergis, K., Birkedal-Hansen, H. & Everts, V., Dec 2002, In: European Journal of Oral Sciences. 110, 6, p. 445-51 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Collagen dissolution by keratinocytes requires cell surface plasminogen activation and matrix metalloproteinase activity

    Netzel-Arnett, S., Mitola, D. J., Yamada, S. S., Chrysovergis, K., Holmbeck, Kenn, Birkedal-Hansen, H. & Bugge, T. H., 22 Nov 2002, In: The Journal of Biological Chemistry. 277, 47, p. 45154-61 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Matrix metalloproteinases (MMPs) regulate fibrin-invasive activity via MT1-MMP-dependent and -independent processes

    Hotary, K. B., Yana, I., Sabeh, F., Li, X., Holmbeck, Kenn, Birkedal-Hansen, H., Allen, E. D., Hiraoka, N. & Weiss, S. J., 4 Feb 2002, In: The Journal of Experimental Medicine. 195, 3, p. 295-308 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    MT1-MMP-dependent and -independent regulation of gelatinase A activation in long-term, ascorbate-treated fibroblast cultures: regulation by fibrillar collagen

    Ruangpanit, N., Price, J. T., Holmbeck, Kenn, Birkedal-Hansen, H., Guenzler, V., Huang, X., Chan, D., Bateman, J. F. & Thompson, E. W., 15 Jan 2002, In: Experimental Cell Research. 272, 2, p. 109-18 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. 2001
  70. Published

    A regulatory cascade involving retinoic acid, Cbfa1, and matrix metalloproteinases is coupled to the development of a process of perichondrial invasion and osteogenic differentiation during bone formation

    Jiménez, M. J., Balbín, M., Alvarez, J., Komori, T., Bianco, P., Holmbeck, Kenn, Birkedal-Hansen, H., López, J. M. & López-Otín, C., 24 Dec 2001, In: The Journal of Cell Biology. 155, 7, p. 1333-44 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Gelatinase A (MMP-2) activation by skin fibroblasts: dependence on MT1-MMP expression and fibrillar collagen form

    Ruangpanit, N., Chan, D., Holmbeck, Kenn, Birkedal-Hansen, H., Polarek, J., Yang, C., Bateman, J. F. & Thompson, E. W., Jun 2001, In: Matrix Biology. 20, 3, p. 193-203 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. 1999
  73. Published

    MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover

    Holmbeck, Kenn, Bianco, P., Caterina, J., Yamada, S., Kromer, M., Kuznetsov, S. A., Mankani, M., Robey, P. G., Poole, A. R., Pidoux, I., Ward, J. M. & Birkedal-Hansen, H., 1 Oct 1999, In: Cell. 99, 1, p. 81-92 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 164419721