Kenn Holmbeck

Kenn Holmbeck

Associate Professor


  1. 2023
  2. Published
  3. Published

    Full-length sequence analysis of hepatitis C virus genotype 3b strains and development of an in vivo infectious 3b cDNA clone

    Bajpai, P. S., Collignon, Laura Maria F, Sølund, C., Madsen, L. W., Christensen, P. B., Øvrehus, A., Weis, Nina, Holmbeck, Kenn, Fahnøe, Ulrik & Bukh, Jens, 2023, In: Journal of Virology. 97, 12, 23 p., 00925.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide

    Sherwood, A. V., Rivera-Rangel, L. R., Ryberg, L. A., Larsen, H. S., Anker, K. M., Costa, R., Vågbø, C. B., Jakljevič, E., Pham, L. V., Fernandez-Antunez, C., Indrisiunaite, G., Podolska-Charlery, A., Grothen, J. E. R., Langvad, N. W., Fossat, N., Offersgaard, A., Al-Chaer, A., Nielsen, L., Kuśnierczyk, A., Sølund, C. & 8 others, Weis, Nina, Gottwein, Judith Margarete, Holmbeck, Kenn, Bottaro, S., Ramirez Almeida, Santseharay, Bukh, Jens, Scheel, Troels Kasper Høyer & Vinther, Jeppe, 2023, In: Nature. 619, p. 811-818

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Molecular Determinants of Mouse Adaptation of Rat Hepacivirus

    Wolfisberg, R., Holmbeck, Kenn, Billerbeck, E., Thorselius, Caroline Eva, Batista, M. N., Fahnøe, Ulrik, Lundsgaard, Emma Alberte, Kennedy, Matthew James, Nielsen, L., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Journal of Virology. 97, 4, 17 p., e0181222.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2022
  7. Published

    Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals

    Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Holmbeck, K., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P. & 5 others, Ramirez Almeida, Santseharay, Reichl, U., Genzel, Y., Bukh, J. & Gottwein, Judith Margarete, 6 Jul 2022.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  8. Published

    Neutralization and receptor use of infectious culture–derived rat hepacivirus as a model for HCV

    Wolfisberg, R., Thorselius, Caroline Eva, Salinas, E., Elrod, E., Trivedi, S., Nielsen, L., Fahnøe, Ulrik, Kapoor, A., Grakoui, A., Rice, C. M., Bukh, Jens, Holmbeck, Kenn & Scheel, Troels Kasper Høyer, 2022, In: Hepatology. 76, 5, p. 1506-1519

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Novel HCV Genotype 4d Infectious Systems and Assessment of Direct-Acting Antivirals and Antibody Neutralization

    Pham, Long, Velázquez-Moctezuma, R., Fahnøe, Ulrik, Collignon, Laura Maria F, Bajpai, P., Sølund, C., Weis, Nina, Holmbeck, Kenn, Prentø, Jannick & Bukh, Jens, 2022, In: Viruses. 14, 11, 2527.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2019
  11. Published

    Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells

    Wolfisberg, R., Holmbeck, Kenn, Nielsen, L., Kapoor, A., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2019, In: Journal of Virology. 93, 19, 19 p., e00733-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2018
  13. MT3-MMP Promotes Excitatory Synapse Formation by Promoting Nogo-66 Receptor Ectodomain Shedding

    Sanz, R. L., Ferraro, G. B., Kacervosky, J., Salesse, C., Gowing, E., Hua, L., Rambaldi, I., Beaubien, F., Holmbeck, Kenn, Cloutier, J. F., Lévesque, M., Murai, K. & Fournier, A. E., 2018, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 38, 3, p. 518-529 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2017
  15. Btbd7 is essential for region-specific epithelial cell dynamics and branching morphogenesis in vivo

    Daley, W. P., Matsumoto, K., Doyle, A. D., Wang, S., DuChez, B. J., Holmbeck, Kenn & Yamada, K. M., 2017, In: Development (Cambridge). 144, 12, p. 2200-2211 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia

    Mayer, B., Németh, K., Krepuska, M., Myneni, V. D., Maric, D., Tisdale, J. F., Hsieh, M. M., Uchida, N., Lee, H-J., Nemeth, M. J., Holmbeck, K., Noguchi, C. T., Rogers, H., Dey, S., Hansen, A., Hong, J., Chow, I., Key, S., Szalayova, I., Pagani, J. & 6 others, Markó, K., McClain-Caldwell, I., Vitale-Cross, L., Young, W. S., Brownstein, M. J. & Mezey, É., 2017, In: Science Translational Medicine. 9, 418

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2016
  18. Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream

    Langenfurth, A., Gu, S., Bautze, V., Zhang, C., Neumann, J. E., Schüller, U., Stock, K., Wolf, S. A., Maier, A., Mastrella, G., Pak, A., Cheng, H., Kälin, R. E., Holmbeck, Kenn, Strotmann, J., Kettenmann, H. & Glass, R., 30 Aug 2016, In: Scientific Reports. 6, 32203.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo

    Motley, M. P., Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Spencer, D. E., Szabo, R., Holmbeck, Kenn, Flick, M. J., Lawrence, D. A., Castellino, F. J., Weigert, R. & Bugge, T. H., 2016, In: Blood. 127, 9, p. 1085-1096 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Multiple essential MT1-MMP functions in tooth root formation, dentinogenesis, and tooth eruption

    Xu, H., Snider, T. N., Wimer, H. F., Yamada, S. S., Yang, T., Holmbeck, Kenn & Foster, B. L., 2016, In: Matrix Biology. 52-54, p. 266-283 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2015
  22. Mice Deficient in AKAP13 (BRX) Are Osteoporotic and Have Impaired Osteogenesis

    Koide, H., Holmbeck, Kenn, Lui, J. C., Guo, X. C., Driggers, P., Chu, T., Tatsuno, I., Quaglieri, C., Kino, T., Baron, J., Young, M. F., Robey, P. G. & Segars, J. H., Oct 2015, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30, 10, p. 1887-95 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Osteoblast-specific expression of the fibrous dysplasia (FD)-causing mutation Gsα(R201C) produces a high bone mass phenotype but does not reproduce FD in the mouse

    Remoli, C., Michienzi, S., Sacchetti, B., Consiglio, A. D., Cersosimo, S., Spica, E., Robey, P. G., Holmbeck, Kenn, Cumano, A., Boyde, A., Davis, G., Saggio, I., Riminucci, M. & Bianco, P., Jun 2015, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30, 6, p. 1030-43 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling

    Maeda, A., Ono, M., Holmbeck, Kenn, Li, L., Kilts, T. M., Kram, V., Noonan, M. L., Yoshioka, Y., McNerny, E. M. B., Tantillo, M. A., Kohn, D. H., Lyons, K. M., Robey, P. G. & Young, M. F., 2015, In: The Journal of Biological Chemistry. 290, 22, p. 14004-14018 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2014
  26. Biglycan modulates angiogenesis and bone formation during fracture healing

    Berendsen, A. D., Pinnow, E. L., Maeda, A., Brown, A. C., McCartney-Francis, N., Kram, V., Owens, R. T., Robey, P. G., Holmbeck, Kenn, de Castro, L. F., Kilts, T. M. & Young, M. F., Apr 2014, In: Matrix Biology. 35, p. 223-31 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Constitutive expression of Gsα(R201C) in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history

    Saggio, I., Remoli, C., Spica, E., Cersosimo, S., Sacchetti, B., Robey, P. G., Holmbeck, Kenn, Cumano, A., Boyde, A., Bianco, P. & Riminucci, M., 2014, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 29, 11, p. 2357-68 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2010
  29. Published

    Membrane-type MMPs are indispensable for placental labyrinth formation and development

    Szabova, L., Son, M., Shi, J., Sramko, M., Yamada, S. S., Swaim, W. D., Zerfas, P., Kahan, S. & Holmbeck, Kenn, 16 Dec 2010, In: Blood. 116, 25, p. 5752-61 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Carcinomas contain a matrix metalloproteinase-resistant isoform of type I collagen exerting selective support to invasion

    Makareeva, E., Han, S., Vera, J. C., Sackett, D. L., Holmbeck, Kenn, Phillips, C. L., Visse, R., Nagase, H. & Leikin, S., 1 Jun 2010, In: Cancer Research. 70, 11, p. 4366-74 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2009
  32. Published

    MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis

    Rebustini, I. T., Myers, C., Lassiter, K. S., Surmak, A., Szabova, L., Holmbeck, Kenn, Pedchenko, V., Hudson, B. G. & Hoffman, M. P., Oct 2009, In: Developmental Cell. 17, 4, p. 482-93 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion

    Markovic, D. S., Vinnakota, K., Chirasani, S., Synowitz, M., Raguet, H., Stock, K., Sliwa, M., Lehmann, S., Kälin, R., van Rooijen, N., Holmbeck, Kenn, Heppner, F. L., Kiwit, J., Matyash, V., Lehnardt, S., Kaminska, B., Glass, R. & Kettenmann, H., 28 Jul 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 30, p. 12530-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2008
  35. Published

    MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease

    Szabova, L., Chrysovergis, K., Yamada, S. S. & Holmbeck, Kenn, 22 May 2008, In: Oncogene. 27, 23, p. 3274-81 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Development of craniofacial structures in transgenic mice with constitutively active PTH/PTHrP receptor

    Tsutsui, T. W., Riminucci, M., Holmbeck, Kenn, Bianco, P. & Robey, P. G., Feb 2008, In: Bone. 42, 2, p. 321-31 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 164419721