Kenn Holmbeck

Kenn Holmbeck

Associate Professor


  1. 2010
  2. Published

    Carcinomas contain a matrix metalloproteinase-resistant isoform of type I collagen exerting selective support to invasion

    Makareeva, E., Han, S., Vera, J. C., Sackett, D. L., Holmbeck, Kenn, Phillips, C. L., Visse, R., Nagase, H. & Leikin, S., 1 Jun 2010, In: Cancer Research. 70, 11, p. 4366-74 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2009
  4. Published

    MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis

    Rebustini, I. T., Myers, C., Lassiter, K. S., Surmak, A., Szabova, L., Holmbeck, Kenn, Pedchenko, V., Hudson, B. G. & Hoffman, M. P., Oct 2009, In: Developmental Cell. 17, 4, p. 482-93 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion

    Markovic, D. S., Vinnakota, K., Chirasani, S., Synowitz, M., Raguet, H., Stock, K., Sliwa, M., Lehmann, S., Kälin, R., van Rooijen, N., Holmbeck, Kenn, Heppner, F. L., Kiwit, J., Matyash, V., Lehnardt, S., Kaminska, B., Glass, R. & Kettenmann, H., 28 Jul 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 30, p. 12530-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2008
  7. Published

    MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease

    Szabova, L., Chrysovergis, K., Yamada, S. S. & Holmbeck, Kenn, 22 May 2008, In: Oncogene. 27, 23, p. 3274-81 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Development of craniofacial structures in transgenic mice with constitutively active PTH/PTHrP receptor

    Tsutsui, T. W., Riminucci, M., Holmbeck, Kenn, Bianco, P. & Robey, P. G., Feb 2008, In: Bone. 42, 2, p. 321-31 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Membrane-type MMPs enable extracellular matrix permissiveness and mesenchymal cell proliferation during embryogenesis

    Shi, J., Son, M., Yamada, S., Szabova, L., Kahan, S., Chrysovergis, K., Wolf, L., Surmak, A. & Holmbeck, Kenn, 1 Jan 2008, In: Developmental Biology. 313, 1, p. 196-209 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells

    Ingvarsen, S. Z., Madsen, D. H., Hillig, T., Lund, L. R., Holmbeck, Kenn, Behrendt, Niels & Engelholm, L. H., 2008, In: Biological Chemistry. 389, 7, p. 943-953 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2007
  12. Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

    Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, Henrik, Høyer-Hansen, G., Holmbeck, Kenn, Bugge, T. H. & Behrendt, Niels, 14 Sep 2007, In: The Journal of Biological Chemistry. 282, 37, p. 27037-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Complementary roles of intracellular and pericellular collagen degradation pathways in vivo

    Wagenaar-Miller, R. A., Engelholm, Lars Henning, Gavard, J., Yamada, S. S., Gutkind, J. S., Behrendt, Niels, Bugge, T. H. & Holmbeck, Kenn, Sep 2007, In: Molecular and Cellular Biology. 27, 18, p. 6309-22 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Membrane type 1 matrix metalloproteinase is necessary for distal airway epithelial repair and keratinocyte growth factor receptor expression after acute injury

    Atkinson, J. J., Toennies, H. M., Holmbeck, Kenn & Senior, R. M., Sep 2007, In: American Journal of Physiology: Lung Cellular and Molecular Physiology. 293, 3, p. L600-10

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 164419721