Kenn Holmbeck

Kenn Holmbeck

Associate Professor


  1. 1999
  2. Published

    MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover

    Holmbeck, Kenn, Bianco, P., Caterina, J., Yamada, S., Kromer, M., Kuznetsov, S. A., Mankani, M., Robey, P. G., Poole, A. R., Pidoux, I., Ward, J. M. & Birkedal-Hansen, H., 1 Oct 1999, In: Cell. 99, 1, p. 81-92 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2001
  4. Published

    Gelatinase A (MMP-2) activation by skin fibroblasts: dependence on MT1-MMP expression and fibrillar collagen form

    Ruangpanit, N., Chan, D., Holmbeck, Kenn, Birkedal-Hansen, H., Polarek, J., Yang, C., Bateman, J. F. & Thompson, E. W., Jun 2001, In: Matrix Biology. 20, 3, p. 193-203 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A regulatory cascade involving retinoic acid, Cbfa1, and matrix metalloproteinases is coupled to the development of a process of perichondrial invasion and osteogenic differentiation during bone formation

    Jiménez, M. J., Balbín, M., Alvarez, J., Komori, T., Bianco, P., Holmbeck, Kenn, Birkedal-Hansen, H., López, J. M. & López-Otín, C., 24 Dec 2001, In: The Journal of Cell Biology. 155, 7, p. 1333-44 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2002
  7. Published

    MT1-MMP-dependent and -independent regulation of gelatinase A activation in long-term, ascorbate-treated fibroblast cultures: regulation by fibrillar collagen

    Ruangpanit, N., Price, J. T., Holmbeck, Kenn, Birkedal-Hansen, H., Guenzler, V., Huang, X., Chan, D., Bateman, J. F. & Thompson, E. W., 15 Jan 2002, In: Experimental Cell Research. 272, 2, p. 109-18 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Matrix metalloproteinases (MMPs) regulate fibrin-invasive activity via MT1-MMP-dependent and -independent processes

    Hotary, K. B., Yana, I., Sabeh, F., Li, X., Holmbeck, Kenn, Birkedal-Hansen, H., Allen, E. D., Hiraoka, N. & Weiss, S. J., 4 Feb 2002, In: The Journal of Experimental Medicine. 195, 3, p. 295-308 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Collagen dissolution by keratinocytes requires cell surface plasminogen activation and matrix metalloproteinase activity

    Netzel-Arnett, S., Mitola, D. J., Yamada, S. S., Chrysovergis, K., Holmbeck, Kenn, Birkedal-Hansen, H. & Bugge, T. H., 22 Nov 2002, In: The Journal of Biological Chemistry. 277, 47, p. 45154-61 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    On the role of MT1-MMP, a matrix metalloproteinase essential to collagen remodeling, in murine molar eruption and root growth

    Beertsen, W., Holmbeck, Kenn, Niehof, A., Bianco, P., Chrysovergis, K., Birkedal-Hansen, H. & Everts, V., Dec 2002, In: European Journal of Oral Sciences. 110, 6, p. 445-51 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2003
  12. Published

    Inhibition of molar eruption and root elongation in MT1-MMP-deficient mice

    Beertsen, W., Holmbeck, Kenn, Niehof, A., Bianco, P., Chrysovergis, K., Birkedal-Hansen, H. & Everts, V., 2003, In: Connective Tissue Research. 44 Suppl 1, p. 298-9 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

    Engelholm, Lars Henning, List, K., Netzel-Arnett, S., Cukierman, E., Mitola, D. J., Aaronson, H., Kjøller, L., Larsen, J. K., Yamada, K. M., Strickland, D. K., Holmbeck, Kenn, Danø, K., Birkedal-Hansen, H., Behrendt, Niels & Bugge, T. H., 31 Mar 2003, In: Journal of Cell Biology. 160, 7, p. 1009-15 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    MT1-mmp: a collagenase essential for tumor cell invasive growth

    Holmbeck, Kenn, Bianco, P. & Birkedal-Hansen, H., Aug 2003, In: Cancer Cell. 4, 2, p. 83-4 2 p.

    Research output: Contribution to journalJournal articleResearch

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ID: 164419721