Jan Pravsgaard Christensen
Professor
Immunology
Nørre Allé 14
2200 København N
- 2024
- Published
Prevention of respiratory virus transmission by resident memory CD8 + T cells.
Uddbäck, Ida Elin Maria, Michalets, S. E., Saha, A., Mattingly, C., Kost, K. N., Williams, M. E., Lawrence, L. A., Hicks, S. L., Lowen, A. C., Ahmed, H., Thomsen, Allan Randrup, Russell, C. J., Scharer, C. D., Boss, J. M., Koelle, K., Antia, R., Christensen, Jan Pravsgaard & Kohlmeier, J. E., 2024, In: Nature. 626, p. 392–400Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals
Offersgaard, Anna Falden, Duarte Hernandez, Carlos Rene, Feng, S., Marichal-Gallardo, P., Holmbeck, Kenn, Pihl, A. F., Fernandez-Antunez, C., Alzua, G. P., Hartmann, Katrine Top, Pham, Long, Zhou, Y., Gammeltoft, Karen Anbro, Fahnøe, Ulrik, Schneider, Uffe Vest, Pedersen, Gabriel Kristian, Jensen, Henrik Elvang, Christensen, Jan Pravsgaard, Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: iScience. 26, 2, 105949.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice
Skeltved, Nanna, Nordmaj, Mie Anemone, Pagh-Berendtsen, Nicolai, Dagil, Robert, Stormer, E. M. R., Al-Nakouzi, N., Jiang, K., Aicher, A., Heeschen, C., Gustavsson, Tobias, Choudhary, Swati, Gögenur, Ismail, Christensen, Jan Pravsgaard, Theander, Thor Grundtvig, Daugaard, M., Salanti, Ali & Nielsen, Morten Agertoug, 2023, In: Journal of Experimental & Clinical Cancer Research. 42, 16 p., 106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice
Alzua, G. P., Pihl, A. F., Offersgaard, Anna Falden, Duarte Hernandez, Carlos Rene, Duan, Z., Feng, S., Fahnøe, Ulrik, Sølund, C., Weis, Nina, Law, M., Prentø, Jannick, Christensen, Jan Pravsgaard, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Gut. 72, 3, p. 560-572Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Consequences of Peripheral Influenza A Infection on Cell Populations in the Murine Hypothalamus
Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, 31 p.Research output: Working paper › Preprint › Research
- Published
Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus
Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, In: eLife. 12, 28 p., RP87515.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systemic virus infection results in CD8 T cell recruitment to the retina in the absence of local virus infection
Paskeviciute, E., Chen, M., Xu, H., Honoré, B., Vorum, H., Sørensen, Torben Lykke, Christensen, Jan Pravsgaard, Thomsen, Allan Randrup, Nissen, Mogens Holst & Steffensen, Maria Abildgaard, 2023, In: Frontiers in Immunology. 14, 1221511.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vaccine induced memory CD8+ T cells efficiently prevent viral transmission from the respiratory tract.
Zhou, Jinglin, Uddbäck, Ida Elin Maria, Kohlmeier, J. E., Christensen, Jan Pravsgaard & Thomsen, Allan Randrup, 2023, In: Frontiers in Immunology. 14, 13 p., 1322536.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals
Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P., Ramirez Almeida, S. & 4 others, , 6 Jul 2022.Research output: Contribution to conference › Poster › Communication
- Published
Establishment of high-titer HCV and SARS-CoV-2 production in a scalable packed-bed bioreactor for inactivated vaccines inducing neutralizing antibodies in animals
Offersgaard, A. F., Hernandez, C. R. D., Finne Pihl, A., Feng, S., Marichal-Gallardo, P., Holmbeck, K., Venkatesan, N. P., Lin, X., Fernandez-Antunez, C., Pena Alzua, G., Costa, R., Hartmann, K. T., Pham, L., Zhou, Y., Gammeltoft, K. A., Fahnøe, U., Scheel, T. K. H., Schneider, U. V., Jensen, H. E., Christensen, J. P. & 5 others, , 6 Jul 2022.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
A Novel H-2d Epitope for Influenza A Polymerase Acidic Protein
Uddbäck, Ida Elin Maria, Kohlmeier, J. E., Thomsen, Allan Randrup & Christensen, Jan Pravsgaard, 2022, In: Viruses. 14, 3, 601.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional in vitro models of the inhibitory effect of adipose tissue-derived stromal cells on lymphocyte proliferation: Improved sensitivity and quantification through flow cytometric analysis
Juhl, M., Follin, Bjarke, Christensen, Jan Pravsgaard, Kastrup, J. & Ekblond, A., 2022, In: Journal of Immunological Methods. 510, 113360.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPR183 is Dispensable for B1 cell Accumulation and Function, but Affects B2 cell Abundance, in the Omentum and Peritoneal Cavity
Barington, L., Christensen, Liv von Voss, Pedersen, K. K., Arfelt, K. N., Roumain, M., Jensen, Kristian HR, Kjær, Viktoria Madeline Skovgaard, Daugvilaite, V., Kearney, J. F., Christensen, Jan Pravsgaard, Hjortø, Gertrud Malene, Muccioli, G. G., Holst, Peter Johannes & Rosenkilde, Mette, 2022, In: Cells. 11, 3, 19 p., 494.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inactivated whole hepatitis C virus vaccine employing a licensed adjuvant elicits cross-genotype neutralizing antibodies in mice
Pihl, A. F., Feng, S., Offersgaard, Anna Falden, Alzua, G. P., Augestad, Elias Honerød, Mathiesen, C. K., Jensen, T. B., Krarup, H., Law, M., Prentø, Jannick, Christensen, Jan Pravsgaard, Bukh, Jens & Gottwein, Judith Margarete, 2022, In: Journal of Hepatology. 76, 5, p. 1051-1061Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Persistent Antigen Harbored by Alveolar Macrophages Enhances the Maintenance of Lung-Resident Memory CD8+ T Cells
Lobby, J. L., Uddbäck, Ida Elin Maria, Scharer, C. D., Mi, T., Boss, J. M., Thomsen, Allan Randrup, Christensen, Jan Pravsgaard & Kohlmeier, J. E., 2022, In: Journal of Immunology. 209, 9, p. 1778-1787Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
Fougeroux, C., Goksøyr, L., Idorn, M., Soroka, V., Myeni, S. K., Dagil, R., Janitzek, C. M., Søgaard, M., Aves, K-L., Horsted, E. W., Erdogan, S. M., Gustavsson, T., Dorosz, J., Clemmensen, S., Fredsgaard, L., Thrane, S., Vidal-Calvo, E. E., Khalifé, P., Hulen, T. M., Choudhary, S. & 27 others, , 2021, In: Nature Communications. 12, 1, p. 324Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cryopreservation of peripheral blood mononuclear cells for use in proliferation assays: First step towards potency assays
Juhl, M., Christensen, Jan Pravsgaard, Pedersen, Anders Elm, Kastrup, J. & Ekblond, A., 2021, In: Journal of Immunological Methods. 488, 112897.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytotoxic CD8+ T cells in cancer and cancer immunotherapy
Raskov, H., Orhan, Adile, Christensen, Jan Pravsgaard & Gögenur, Ismail, 2021, In: British Journal of Cancer. 124, p. 359–367 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Efficient control of zika virus infection induced by a non-replicating adenovector encoding zika virus ns1/ns2 antigens fused to the mhc class ii-associated invariant chain
Nazerai, L., Buus, Søren, Buus, Anette Stryhn, Thomsen, Allan Randrup & Christensen, Jan Pravsgaard, 2021, In: Viruses. 13, 11, 2215.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functionally Competent, PD-1+ CD8+ Trm Cells Populate the Brain Following Local Antigen Encounter
Schøller, A. S., Nazerai, L., Christensen, Jan Pravsgaard & Thomsen, Allan Randrup, 2021, In: Frontiers in Immunology. 11, 17 p., 595707.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term maintenance of lung resident memory T cells is mediated by persistent antigen
Uddbäck, Ida Elin Maria, Cartwright, E. K., Schøller, A. S., Wein, A. N., Hayward, S. L., Takamura, S., Thomsen, Allan Randrup, Kohlmeier, J. E. & Christensen, Jan Pravsgaard, 2021, In: Mucosal Immunology. 14, p. 92-99Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Th1/Th17 T cell Tissue-Resident Immunity Increases Protection, But Is Not Required in a Vaccine Strategy Against Genital Infection With Chlamydia trachomatis
Nguyen, N. D. N. T., Guleed, S., Olsen, A. W., Follmann, F., Christensen, Jan Pravsgaard & Dietrich, J., 2021, In: Frontiers in Immunology. 12, 790463.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
A Systematic, Unbiased Mapping of CD8+ and CD4+ T Cell Epitopes in Yellow Fever Vaccinees
Buus, Anette Stryhn, Kongsgaard, M., Rasmussen, M., Harndahl, M. N., Østerbye, Thomas, Bassi, Maria Rosaria, Thybo, S., Gabriel, M., Hansen, Morten Bagge, Nielsen, M., Christensen, Jan Pravsgaard, Thomsen, Allan Randrup & Buus, Søren, 31 Aug 2020, In: Frontiers in Immunology. 11, 25 p., 1836.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A vaccine displaying a trimeric influenza-A HA stem protein on capsid-like particles elicits potent and long-lasting protection in mice
Thrane, Susan, Aves, Kara-Lee, Uddbäck, Ida Elin Maria, Janitzek, C. M., Han, J., Yang, Y. R., Ward, A. B., Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Thomsen, Allan Randrup, Christensen, Jan Pravsgaard & Sander, Adam F. , 2020, In: Vaccines. 8, 3, 389.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effector CD8 T Cell-Dependent Zika Virus Control in the CNS: A Matter of Time and Numbers
Nazerai, L., Schøller, A. S., Bassi, Maria Rosaria, Buus, Søren, Buus, Anette Stryhn, Christensen, Jan Pravsgaard & Thomsen, Allan Randrup, 2020, In: Frontiers in Immunology. 11, 16 p., 1977.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3879
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2080
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Increased immunogenicity and protective efficacy of influenza M2e fused to a tetramerizing protein
Research output: Contribution to journal › Journal article › Research › peer-review
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1659
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Vesicular stomatitis virus infection promotes immune evasion by preventing NKG2D-ligand surface expression
Research output: Contribution to journal › Journal article › Research › peer-review
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1079
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The availability of a functional tumor targeting T-cell repertoire determines the anti-tumor efficiency of combination therapy with anti-CTLA-4 and anti-4-1BB antibodies
Research output: Contribution to journal › Journal article › Research › peer-review
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