Jens Bukh

Jens Bukh

Professor

Member of:

    ORCID: 0000-0002-7815-4806

    Publication year:
    All
    1 - 17 out of 17Page size: 25
    1. 2013
    2. Published

      Efficient cell culture system for hepatitis C virus genotype 5A: Patent #: 8,618,275

      Jensen, T. B., Gottwein, Judith Margarete, Scheel, T. K. H., Eugen-Olsen, J. & Bukh, Jens, 31 Dec 2013, IPC No. C07H 21/00 (20060101); C12N 7/00 (20060101); A61K 39/295 (20060101); A61K 39/12 (20060101); A61K 39/29 (20060101), Patent No. WO2008/141651, 27 Nov 2008, Priority date 19 May 2008, Priority No. PCT/DK2008/050113

      Research output: Patent

    3. Published

      Adapted J6/JFH1-based Hepatitis C virus recombinants with genotype-specific NS4A show similar efficacies against lead protease inhibitors, alpha interferon, and a putative NS4A inhibitor

      Gottwein, Judith Margarete, Jensen, S. B., Serre, S. B. N., Ghanem, L., Scheel, Troels Kasper Høyer, Jensen, T. B., Krarup, H., Uzcategui, N., Mikkelsen, L. S. & Bukh, Jens, Dec 2013, In: Antimicrobial Agents and Chemotherapy. 57, 12, p. 6034-49 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Identification of alpha interferon-induced envelope mutations of hepatitis C virus in vitro associated with increased viral fitness and interferon resistance

      Serre, S. B. N., Krarup, H. B., Bukh, Jens & Gottwein, Judith Margarete, Dec 2013, In: Journal of Virology. 87, 23, p. 12776-93 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Persistent human hepatitis B virus infection in cynomolgus monkeys: a novel animal model in the search for a cure?

      Bukh, Jens, Lanford, R. E. & Purcell, R. H., Nov 2013, In: Hepatology. 58, 5, p. 1533-6 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Efficient cell culture system for hepatitis C virus genotype 6A: Patent #: 8,569,472

      Gottwein, Judith Margarete, Scheel, T. K. H., Jensen, T. B. & Bukh, Jens, 29 Oct 2013, IPC No. C07H 21/00 (20060101); C12N 7/00 (20060101); A61K 39/295 (20060101); A61K 39/12 (20060101); A61K 39/29 (20060101), Patent No. WO2009/080052, 2 Jul 2009, Priority date 19 Dec 2008, Priority No. PCT/DK2008/050332

      Research output: Patent

    7. Published

      Efficient cell culture system for hepatitis C virus genotype 1a and 1b: Patent #: 8,563,706

      Scheel, T. K. H., Gottwein, Judith Margarete, Prentø, Jannick, Jensen, T. B. & Bukh, Jens, 22 Oct 2013, IPC No. C07H 21/00 (20060101); A61K 39/29 (20060101); A61K 39/12 (20060101); A61K 39/295 (20060101); C12N 7/00 (20060101), Patent No. WO2009/080053, 2 Jul 2009, Priority date 19 Dec 2008, Priority No. PCT/DK2008/050333

      Research output: Patent

    8. Published

      Analysis of hepatitis C virus core/NS5A protein co-localization using novel cell culture systems expressing core-NS2 and NS5A of genotypes 1-7

      Galli, A., Scheel, Troels Kasper Høyer, Prentø, Jannick, Mikkelsen, L. S., Gottwein, Judith Margarete & Bukh, Jens, Oct 2013, In: The Journal of general virology. 94, Pt 10, p. 2221-35 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Viral hepatitis: Cell-culture-derived HCV--a promising vaccine antigen

      Gottwein, Judith Margarete & Bukh, Jens, Sep 2013, In: Nature Reviews. Gastroenterology & Hepatology. 10, 9, p. 508-9 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Efficient cell culture system for hepatitis C virus genotype 7a: Patent #: 8,506,969

      Gottwein, Judith Margarete, Scheel, T. K. H., Jensen, T. B. & Bukh, Jens, 13 Aug 2013, IPC No. A61K 39/12 (20060101); A61K 39/29 (20060101); C12Q 1/70 (20060101); C12N 15/00 (20060101); C12N 5/071 (20100101); C12N 1/20 (20060101), Patent No. WO2010/017819, 18 Feb 2010, Priority date 31 Jul 2009, Priority No. PCT/DK2009/050193

      Research output: Patent

    11. Published

      Adaptive mutations allow establishment of JFH1-based cell culture systems for hepatitis C virus genotype 4A: Patent #: 8,454,974

      Scheel, T. K. H., Gottwein, Judith Margarete, Eugen-Olsen, J. & Bukh, Jens, 4 Jun 2013, IPC No. A61K 39/29 (20060101); C07H 21/00 (20060101); C12N 15/06 (20060101); C12N 7/02 (20060101); C12Q 1/02 (20060101), Patent No. WO2008/125119, 23 Oct 2008, Priority date 11 Apr 2008, Priority No. PCT/DK2008/050085

      Research output: Patent

    12. Published

      Combination treatment with hepatitis C virus protease and NS5A inhibitors is effective against recombinant genotype 1a, 2a, and 3a viruses

      Gottwein, Judith Margarete, Jensen, S. B., Li, Y., Ghanem, L., Scheel, Troels Kasper Høyer, Serre, S. B. N., Mikkelsen, L. & Bukh, Jens, Mar 2013, In: Antimicrobial Agents and Chemotherapy. 57, 3, p. 1291-303 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Productive homologous and non-homologous recombination of hepatitis C virus in cell culture

      Scheel, Troels Kasper Høyer, Galli, A., Li, Y., Mikkelsen, L. S., Gottwein, Judith Margarete & Bukh, Jens, Mar 2013, In: P L o S Pathogens. 9, 3, p. 1-12 13 p., e1003228.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      A hepatitis C virus (HCV) vaccine comprising envelope glycoproteins gpE1/gpE2 derived from a single isolate elicits broad cross-genotype neutralizing antibodies in humans

      Law, J. L. M., Chen, C., Wong, J., Hockman, D., Santer, D. M., Frey, S. E., Belshe, R. B., Wakita, T., Bukh, Jens, Jones, C. T., Rice, C. M., Abrignani, S., Tyrrell, D. L. & Houghton, M., 2013, In: PloS one. 8, 3, p. 1-7 8 p., e59776.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Characterization of hepatitis C virus recombinants with chimeric E1/E2 envelope proteins and identification of single amino acids in the E2 stem region important for entry

      Carlsen, T. H. R., Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Foung, S. K. H. & Bukh, Jens, 2013, In: Journal of Virology. 87, 3, p. 1385-99 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Cooperativity in virus neutralization by human monoclonal antibodies to two adjacent regions located at the amino terminus of hepatitis C virus E2 glycoprotein

      Keck, Z., Wang, W., Wang, Y., Lau, P., Carlsen, T. H. R., Prentø, Jannick, Xia, J., Patel, A. H., Bukh, Jens & Foung, S. K. H., 2013, In: Journal of Virology. 87, 1, p. 37-51 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Neutralization resistance of hepatitis C virus can be overcome by recombinant human monoclonal antibodies

      Pedersen, J. L., Carlsen, T. H. R., Prentø, Jannick, Ramirez, S., Jensen, T. B., Forns, X., Alter, H., Foung, S. K. H., Law, M., Gottwein, Judith Margarete, Weis, Nina & Bukh, Jens, 2013, In: Hepatology. 58, 5, p. 1587-1597 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Neutralizing antibodies in patients with chronic hepatitis C, genotype 1, against a panel of genotype 1 culture viruses

      Pedersen, J., Jensen, T. B., Carlsen, T. H. R., Schønning, Kristian, Christensen, P. B., Laursen, A. L., Krarup, H., Bukh, Jens & Weis, Nina, 2013, In: P L o S One. 8, 5, 16 p., e62674.

      Research output: Contribution to journal › Journal article › Research › peer-review

    ID: 12437