Thomas Litman

Thomas Litman

Professor

Member of:

    ORCID: 0000-0002-6068-901X

    Introductory remarks on publicationslist

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    Publication year:
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    1 - 50 out of 140Page size: 50
    1. 1995
    2. Published

      Lipid composition of sensitive and multidrug resistant Ehrlich ascites tumour cells

      Litman, Thomas, Nielsen, D., Skovsgaard, T. & Bukhave, K., 1995, In: Cellular Pharmacology. Vol 2, p. 9-14

      Research output: Contribution to journal › Journal article › Research

    3. 1997
    4. Published

      ATPase activity of P-glycoprotein related to emergence of drug resistance in Ehrlich ascites tumor cell lines

      Litman, Thomas, Nielsen, D., Skovsgaard, T., Zeuthen, Thomas & Stein, W. D., 1997, In: BBA General Subjects. 1361, 2, p. 147-158

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity

      Litman, Thomas, Zeuthen, Thomas, Skovsgaard, T. & Stein, W. D., 1997, In: BBA General Subjects. vol. 1361, p. 169-176

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Drug accumulation in the presence of the multidrug resistance pump: dissociation between verapamil accumulation and the action of P-glycoprotein

      Ayesh, S., Litman, Thomas & Stein, W. D., 1997, In: Receptors and Channels. 5, 3-4, p. 175-83 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Structure-activity relationships of P-glycoprotein interacting drugs: kinetic characterization of their effects on ATPase activity

      Litman, Thomas, Zeuthen, Thomas, Skovsgaard, T. & Stein, W. D., 1997, In: BBA General Subjects. 1361, 2, p. 159-168

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Water transport by the Na+/glucose cotransporter under isotonic conditions

      Zeuthen, Thomas, Meinild, A. K., Klaerke, D. A., Loo, D. D., Wright, E. M., Belhage, B. & Litman, Thomas, 1997, In: Biology of the Cell. 89, 5-6, p. 307-12 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Water transport by the Na+/glucose cotransporter under isotonic conditions

      Zeuthen, T., Meinild, A. K., Klærke, D., Loo, D. D. F., Wright, E. M., Belhage, B. & Litman, Thomas, 1997, In: Biology of the Cell. Vol. 89, p. 307-312

      Research output: Contribution to journal › Journal article › Research

    10. Published

      The multidrug resistant phenotype - A comparative study

      Litman, Thomas, 1 Dec 1997, In: Ugeskrift for Laeger. 159, 6, p. 771-772 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. 1998
    12. Published

      pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells

      Litman, Thomas, Pedersen, Stine Helene Falsig, Kramhøft, B., Skovsgaard, T. & Hoffmann, E. K., 1998, In: Cell. Physiol. Biochem.. 8, p. 138-150

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells

      Litman, Thomas, Pedersen, S. F., Kramhøft, B., Skovsgaard, T. & Hoffmann, E. K., 1998, In: Cellular Physiology and Biochemistry. 8, 3, p. 138-50 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. 1999
    15. Published

      Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833

      Robey, R., Bakke, S., Stein, W., Meadows, B., Litman, Thomas, Patil, S., Smith, T., Fojo, T. & Bates, S., 1 Jan 1999, In: Blood. 93, 1, p. 306-14 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

      Miyake, K., Mickley, L., Litman, Thomas, Zhan, Z., Robey, R., Cristensen, B., Brangi, M., Greenberger, L., Dean, M., Fojo, T. & Bates, S. E., 1 Jan 1999, In: Cancer Research. 59, 1, p. 8-13 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR

      de Bruin, M., Miyake, K., Litman, Thomas, Robey, R. & Bates, S. E., 15 Nov 1999, In: Cancer Letters. 146, 2, p. 117-26 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

      Brangi, M., Litman, Thomas, Ciotti, M., Nishiyama, K., Kohlhagen, G., Takimoto, C., Robey, R., Pommier, Y., Fojo, T. & Bates, S. E., 1 Dec 1999, In: Cancer Research. 59, 23, p. 5938-46 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. 2000
    20. Published

      Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone

      Nielsen, D., Eriksen, J., Maare, C., Litman, Thomas, Kjaersgaard, E., Plesner, T., Friche, E. & Skovsgaard, T., 2000, In: Biochem Pharmacol.. 363-370, p. 60

      Research output: Contribution to journal › Journal article › Research

    21. Published

      The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane

      Rocchi, E., Khodjakov, A., Volk, E. L., Yang, C. H., Litman, Thomas, Bates, S. E. & Schneider, E., 29 Apr 2000, In: Biochemical and Biophysical Research Communications. 271, 1, p. 42-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

      Litman, Thomas, Brangi, M., Hudson, E., Fetsch, P., Abati, A., Ross, D. D., Miyake, K., Resau, J. H. & Bates, S. E., Jun 2000, In: Journal of Cell Science. 113 ( Pt 11), p. 2011-21 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Characterisation of multidrug-resistant Ehrlich ascites tumour cells selected in vivo for resistance to etoposide

      Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas, Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 353-61 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone

      Nielsen, D., Eriksen, J., Maare, C., Litman, Thomas, Kjaersgaard, E., Plesner, T., Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 363-70 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      New ABC transporters in multi-drug resistance

      Bates, S. E., Robey, R., Knutsen, T., Honjo, Y., Litman, Thomas & Dean, M., 1 Oct 2000, In: Expert Opinion On Therapeutic Targets. 4, 5, p. 561-580 20 p.

      Research output: Contribution to journal › Review › Research › peer-review

    26. 2001
    27. Published

      A functional assay for detection of the mitoxantrone resistance protein MXR (ABCG2)

      Robey, R. W., Miyake, K., van de Laar, A., Honjo, Y., Regis, J. T., Litman, Thomas & Bates, S. E., 2001, In: BBA General Subjects. 1512, p. 171-182

      Research output: Contribution to journal › Journal article › Research

    28. Published

      Cellular and biophysical evidence for interactions between Adenosine Triphosphate and P-Glycoprotein substrates: Functional implications for Adenosine Triphosphate/Drug Cotransport in P-Glycoprotein overexpressing tumor cells and in P-Glycoprotein low-level expressing erythrocytes

      Abraham, E. H., Shrivastav, B., Salikova, A. Y., Sterling, K. M., Johnston, N., Guidotti, G., Scala, S., Litman, Thomas, Chan, K. C., Arceci, R. J., Steiglitz, K., Herscher, L. & Okunieff, P., 2001, In: Blood Cells, Molecules and Diseases. 27, p. 181-200

      Research output: Contribution to journal › Journal article › Research

    29. Published

      Expression of P-glycoprotein and multidrug resistance associated protein in Ehrlich ascites tumor cells after fractionated irradiation

      Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas & Skovsgaard, T., 2001, In: Int J Radiat Oncol Biol Phys. 51, p. 1050-1057

      Research output: Contribution to journal › Journal article › Research

    30. Published

      From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance

      Litman, Thomas, Druley, T. E., Stein, W. D. & Bates, S. E., 2001, In: Cell Mol Life Sci.. 931-959, p. 58

      Research output: Contribution to journal › Journal article › Research

    31. Published

      Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

      Ozvegy, C., Litman, Thomas, Szakacs, G., Nagy, Z., Bates, S., Varadi, A. & Sarkadi, B., 2001, In: Biochem. Biophys. Res. Commun.. 285, p. 111-117

      Research output: Contribution to journal › Journal article › Research

    32. Published

      Overexpression of the mitoxantrone resistance ATP binding cassette half-transporter, ABCG2 (BCRP/MXR/ABCP), in flavopiridol-resistant human breast cancer cells

      Robey, R. W., Medina-Perez, W. Y., Nishiyama, K., Litman, Thomas, Miyake, K., Senderowicz, A. M. & Bates, S., 2001, In: Clinical Cancer Research. 7, p. 145-152

      Research output: Contribution to journal › Journal article › Research

    33. Published

      The role of half-transporters in multidrug resistance

      Bates, S. E., Robey, R., Miyake, K., Rao, K., Ross, D. D. & Litman, Thomas, 2001, In: J Bioenerg Biomembr. 503-511, p. 33

      Research output: Contribution to journal › Journal article › Research

    34. Published

      Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells

      Robey, R. W., Medina-Pérez, W. Y., Nishiyama, K., Lahusen, T., Miyake, K., Litman, Thomas, Senderowicz, A. M., Ross, D. D. & Bates, S. E., Jan 2001, In: Clinical Cancer Research. 7, 1, p. 145-52 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Cellular and biophysical evidence for interactions between adenosine triphosphate and P-glycoprotein substrates: functional implications for adenosine triphosphate/drug cotransport in P-glycoprotein overexpressing tumor cells and in P-glycoprotein low-level expressing erythrocytes

      Abraham, E. H., Shrivastav, B., Salikhova, A. Y., Sterling, K. M., Johnston, N., Guidotti, G., Scala, S., Litman, Thomas, Chan, K. C., Arceci, R. J., Steiglitz, K., Herscher, L. & Okunieff, P., 19 May 2001, In: Blood Cells, Molecules and Diseases. 27, 1, p. 181-200 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance

      Litman, Thomas, Druley, T. E., Stein, W. D. & Bates, S. E., Jun 2001, In: Cellular and molecular life sciences : CMLS. 58, 7, p. 931-59 29 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)

      Robey, R. W., Honjo, Y., van de Laar, A., Miyake, K., Regis, J. T., Litman, Thomas & Bates, S. E., 6 Jun 2001, In: BBA General Subjects. 1512, 2, p. 171-82 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

      Ozvegy, C., Litman, Thomas, Szakács, G., Nagy, Z., Bates, S., Váradi, A. & Sarkadi, B., 6 Jul 2001, In: Biochemical and Biophysical Research Communications. 285, 1, p. 111-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells

      Honjo, Y., Hrycyna, C. A., Yan, Q. W., Medina-Pérez, W. Y., Robey, R. W., van de Laar, A., Litman, Thomas, Dean, M. & Bates, S. E., 15 Sep 2001, In: Cancer Research. 61, 18, p. 6635-6639 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Expression of P-glycoprotein and multidrug resistance associated protein in Ehrlich ascites tumor cells after fractionated irradiation

      Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas & Skovsgaard, T., 15 Nov 2001, In: International Journal of Radiation Oncology, Biology, Physics. 51, 4, p. 1050-7 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      The role of half-transporters in multidrug resistance

      Bates, S. E., Robey, R., Miyake, K., Rao, K., Ross, D. D. & Litman, Thomas, Dec 2001, In: Journal of Bioenergetics and Biomembranes. 33, 6, p. 503-11 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. 2002
    43. Published

      Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells

      Poulsen, K. A., Litman, Thomas, Eriksen, J., Mollerup, J. & Lambert, Ian Henry, 2002, In: Amino Acids. 22, p. 333-350

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Functional analysis of candidate ABC transporters proteins for sitosterol transport

      Albrecht, C., Elliott, J. I., Sardini, A., Litman, Thomas, Stieger, B., Meier, P. J. & Higgins, C. F., 2002, In: Biochem. Biophys. Acta. 133-142, p. 1567

      Research output: Contribution to journal › Journal article › Research

    45. Published

      Generation of an activating ZN(2+) switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

      Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 2002, In: Proceedings of the National Academy of Science of the United States of America. vol. 99(3), p. 1683-8

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Impact of BCRP/MXR, MRP1 and MDR1/P-Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells

      Stein, U., Lage, H., Jordan, A. D., Walther, W., Bates, S. E., Litman, Thomas, Hohenberger, P. & Dietel, M., 2002, In: International Journal of Cancer. 97, p. 751-760

      Research output: Contribution to journal › Journal article › Research

    47. Published

      Measurement of cell volume changes by fluorescence self-quenching

      Hamann, Steffen, Kiilgaard, J. F., Litman, Thomas, Alvarez-Leefmans, F. J., Winther, B. R. & Zeuthen, Thomas, 2002, In: Journal of Fluorescence. 12, 2, p. 139-145 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

      Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 5 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 3, p. 1683-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Impact of BCRP/MXR, MRP1 and MDR1/P-Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells

      Stein, U., Lage, H., Jordan, A., Walther, W., Bates, S. E., Litman, Thomas, Hohenberger, P. & Dietel, M., 20 Feb 2002, In: International journal of cancer. Journal international du cancer. 97, 6, p. 751-60 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells

      Poulsen, K. A., Litman, Thomas, Eriksen, J., Mollerup, J. & Lambert, Ian Henry, Jun 2002, In: Amino Acids. 22, 4, p. 333-50 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2

      Litman, Thomas, Jensen, U., Hansen, Alastair, Covitz, K., Zhan, Z., Fetsch, P., Abati, A., Hansen, Paul Robert, Horn, T., Skovsgaard, T. & Bates, S. E., 20 Sep 2002, In: BBA General Subjects. 1565, 1, p. 6-16 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Functional analysis of candidate ABC transporter proteins for sitosterol transport

      Albrecht, C., Elliott, J. I., Sardini, A., Litman, Thomas, Stieger, B., Meier, P. J. & Higgins, C. F., 23 Dec 2002, In: BBA General Subjects. 1567, 1-2, p. 133-42 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. 2003
    54. Published

      Pumping of drugs by P-glycoprotein: a two-step process?

      Litman, Thomas, Skovsgaard, T. & Stein, W. D., 2003, In: Pharmacol Exp Ther.. 307(3), p. 846-853

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Pumping of drugs by P-glycoprotein: a two-step process?

      Litman, Thomas, Skovsgaard, T. & Stein, W. D., Dec 2003, In: Journal of Pharmacology and Experimental Therapeutics. 307, 3, p. 846-53 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. 2004
    57. Published

      Bioinformatik, undervisningsformer og IT, Hvad mener de studerende?

      Vestergaard, B. F. & Litman, Thomas, 2004, In: Plexus. Vol. 36 (1), p. 16-9

      Research output: Contribution to journal › Journal article › Research

    58. Published

      Molecular cloning of a K+ channel from the malaria parasite Plasmodium falciparum

      Ellekvist, P., Ricke, C. H., Litman, Thomas, Salanti, Ali, Colding, H., Zeuthen, Thomas & Klærke, Dan Arne, 2004, In: Biochemical and Biophysical Research Communications. 318, 2, p. 477-84 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      A Serial Analysis of Gene Expression (SAGE) Database Analysis of Chemosensitivity: Comparing Solid Tumors with Cell Lines and Comparing Solid Tumors from Different Tissue Origins: comparing solid tumors with cell lines and comparing solid tumors from different tissue origins

      Stein, W. D., Litman, Thomas, Fojo, T. & Bates, S. E., 15 Apr 2004, In: Cancer Research. 64, 8, p. 2805-2816 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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