Thomas Litman

Thomas Litman

Professor

Member of:

    Introductory remarks on publicationslist

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    1. 1995
    2. Published

      Lipid composition of sensitive and multidrug resistant Ehrlich ascites tumour cells

      Litman, Thomas, Nielsen, D., Skovsgaard, T. & Bukhave, K., 1995, In: Cellular Pharmacology. Vol 2, p. 9-14

      Research output: Contribution to journalJournal articleResearch

    3. 1997
    4. Published

      ATPase activity of P-glycoprotein related to emergence of drug resistance in Ehrlich ascites tumor cell lines

      Litman, Thomas, Nielsen, D., Skovsgaard, T., Zeuthen, Thomas & Stein, W. D., 1997, In: BBA General Subjects. 1361, 2, p. 147-158

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity

      Litman, Thomas, Zeuthen, Thomas, Skovsgaard, T. & Stein, W. D., 1997, In: BBA General Subjects. vol. 1361, p. 169-176

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Drug accumulation in the presence of the multidrug resistance pump: dissociation between verapamil accumulation and the action of P-glycoprotein

      Ayesh, S., Litman, Thomas & Stein, W. D., 1997, In: Receptors and Channels. 5, 3-4, p. 175-83 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Structure-activity relationships of P-glycoprotein interacting drugs: kinetic characterization of their effects on ATPase activity

      Litman, Thomas, Zeuthen, Thomas, Skovsgaard, T. & Stein, W. D., 1997, In: BBA General Subjects. 1361, 2, p. 159-168

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Water transport by the Na+/glucose cotransporter under isotonic conditions

      Zeuthen, Thomas, Meinild, A. K., Klaerke, D. A., Loo, D. D., Wright, E. M., Belhage, B. & Litman, Thomas, 1997, In: Biology of the Cell. 89, 5-6, p. 307-12 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Water transport by the Na+/glucose cotransporter under isotonic conditions

      Zeuthen, T., Meinild, A. K., Klærke, D., Loo, D. D. F., Wright, E. M., Belhage, B. & Litman, Thomas, 1997, In: Biology of the Cell. Vol. 89, p. 307-312

      Research output: Contribution to journalJournal articleResearch

    10. Published

      The multidrug resistant phenotype - A comparative study

      Litman, Thomas, 1 Dec 1997, In: Ugeskrift for Laeger. 159, 6, p. 771-772 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. 1998
    12. Published

      pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells

      Litman, Thomas, Pedersen, Stine Helene Falsig, Kramhøft, B., Skovsgaard, T. & Hoffmann, E. K., 1998, In: Cell. Physiol. Biochem.. 8, p. 138-150

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells

      Litman, Thomas, Pedersen, S. F., Kramhøft, B., Skovsgaard, T. & Hoffmann, E. K., 1998, In: Cellular Physiology and Biochemistry. 8, 3, p. 138-50 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. 1999
    15. Published

      Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833

      Robey, R., Bakke, S., Stein, W., Meadows, B., Litman, Thomas, Patil, S., Smith, T., Fojo, T. & Bates, S., 1 Jan 1999, In: Blood. 93, 1, p. 306-14 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

      Miyake, K., Mickley, L., Litman, Thomas, Zhan, Z., Robey, R., Cristensen, B., Brangi, M., Greenberger, L., Dean, M., Fojo, T. & Bates, S. E., 1 Jan 1999, In: Cancer Research. 59, 1, p. 8-13 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR

      de Bruin, M., Miyake, K., Litman, Thomas, Robey, R. & Bates, S. E., 15 Nov 1999, In: Cancer Letters. 146, 2, p. 117-26 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

      Brangi, M., Litman, Thomas, Ciotti, M., Nishiyama, K., Kohlhagen, G., Takimoto, C., Robey, R., Pommier, Y., Fojo, T. & Bates, S. E., 1 Dec 1999, In: Cancer Research. 59, 23, p. 5938-46 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. 2000
    20. Published

      Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone

      Nielsen, D., Eriksen, J., Maare, C., Litman, Thomas, Kjaersgaard, E., Plesner, T., Friche, E. & Skovsgaard, T., 2000, In: Biochem Pharmacol.. 363-370, p. 60

      Research output: Contribution to journalJournal articleResearch

    21. Published

      The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane

      Rocchi, E., Khodjakov, A., Volk, E. L., Yang, C. H., Litman, Thomas, Bates, S. E. & Schneider, E., 29 Apr 2000, In: Biochemical and Biophysical Research Communications. 271, 1, p. 42-6 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

      Litman, Thomas, Brangi, M., Hudson, E., Fetsch, P., Abati, A., Ross, D. D., Miyake, K., Resau, J. H. & Bates, S. E., Jun 2000, In: Journal of Cell Science. 113 ( Pt 11), p. 2011-21 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Characterisation of multidrug-resistant Ehrlich ascites tumour cells selected in vivo for resistance to etoposide

      Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas, Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 353-61 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone

      Nielsen, D., Eriksen, J., Maare, C., Litman, Thomas, Kjaersgaard, E., Plesner, T., Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 363-70 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      New ABC transporters in multi-drug resistance

      Bates, S. E., Robey, R., Knutsen, T., Honjo, Y., Litman, Thomas & Dean, M., 1 Oct 2000, In: Expert Opinion On Therapeutic Targets. 4, 5, p. 561-580 20 p.

      Research output: Contribution to journalReviewResearchpeer-review

    26. 2001
    27. Published

      A functional assay for detection of the mitoxantrone resistance protein MXR (ABCG2)

      Robey, R. W., Miyake, K., van de Laar, A., Honjo, Y., Regis, J. T., Litman, Thomas & Bates, S. E., 2001, In: BBA General Subjects. 1512, p. 171-182

      Research output: Contribution to journalJournal articleResearch

    28. Published

      Cellular and biophysical evidence for interactions between Adenosine Triphosphate and P-Glycoprotein substrates: Functional implications for Adenosine Triphosphate/Drug Cotransport in P-Glycoprotein overexpressing tumor cells and in P-Glycoprotein low-level expressing erythrocytes

      Abraham, E. H., Shrivastav, B., Salikova, A. Y., Sterling, K. M., Johnston, N., Guidotti, G., Scala, S., Litman, Thomas, Chan, K. C., Arceci, R. J., Steiglitz, K., Herscher, L. & Okunieff, P., 2001, In: Blood Cells, Molecules and Diseases. 27, p. 181-200

      Research output: Contribution to journalJournal articleResearch

    29. Published

      Expression of P-glycoprotein and multidrug resistance associated protein in Ehrlich ascites tumor cells after fractionated irradiation

      Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas & Skovsgaard, T., 2001, In: Int J Radiat Oncol Biol Phys. 51, p. 1050-1057

      Research output: Contribution to journalJournal articleResearch

    30. Published

      From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance

      Litman, Thomas, Druley, T. E., Stein, W. D. & Bates, S. E., 2001, In: Cell Mol Life Sci.. 931-959, p. 58

      Research output: Contribution to journalJournal articleResearch

    31. Published

      Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

      Ozvegy, C., Litman, Thomas, Szakacs, G., Nagy, Z., Bates, S., Varadi, A. & Sarkadi, B., 2001, In: Biochem. Biophys. Res. Commun.. 285, p. 111-117

      Research output: Contribution to journalJournal articleResearch

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