Thomas Litman

Thomas Litman

Professor

Member of:

    ORCID: 0000-0002-6068-901X

    Introductory remarks on publicationslist

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    1. Published

      Cellular and biophysical evidence for interactions between adenosine triphosphate and P-glycoprotein substrates: functional implications for adenosine triphosphate/drug cotransport in P-glycoprotein overexpressing tumor cells and in P-glycoprotein low-level expressing erythrocytes

      Abraham, E. H., Shrivastav, B., Salikhova, A. Y., Sterling, K. M., Johnston, N., Guidotti, G., Scala, S., Litman, Thomas, Chan, K. C., Arceci, R. J., Steiglitz, K., Herscher, L. & Okunieff, P., 19 May 2001, In: Blood Cells, Molecules and Diseases. 27, 1, p. 181-200 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Cellular and biophysical evidence for interactions between Adenosine Triphosphate and P-Glycoprotein substrates: Functional implications for Adenosine Triphosphate/Drug Cotransport in P-Glycoprotein overexpressing tumor cells and in P-Glycoprotein low-level expressing erythrocytes

      Abraham, E. H., Shrivastav, B., Salikova, A. Y., Sterling, K. M., Johnston, N., Guidotti, G., Scala, S., Litman, Thomas, Chan, K. C., Arceci, R. J., Steiglitz, K., Herscher, L. & Okunieff, P., 2001, In: Blood Cells, Molecules and Diseases. 27, p. 181-200

      Research output: Contribution to journal › Journal article › Research

    3. Published

      Functional analysis of candidate ABC transporter proteins for sitosterol transport

      Albrecht, C., Elliott, J. I., Sardini, A., Litman, Thomas, Stieger, B., Meier, P. J. & Higgins, C. F., 23 Dec 2002, In: BBA General Subjects. 1567, 1-2, p. 133-42 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Functional analysis of candidate ABC transporters proteins for sitosterol transport

      Albrecht, C., Elliott, J. I., Sardini, A., Litman, Thomas, Stieger, B., Meier, P. J. & Higgins, C. F., 2002, In: Biochem. Biophys. Acta. 133-142, p. 1567

      Research output: Contribution to journal › Journal article › Research

    5. Published

      Regional differences in neuroinflammation-associated gene expression in the brain of sporadic creutzfeldt–jakob disease patients

      Areškevičiūtė, A., Litman, Thomas, Broholm, H., Melchior, L. C., Nielsen, P. R., Green, A., Eriksen, J. O., Smith, C. & Lund, Eva Løbner, 2021, In: International Journal of Molecular Sciences. 22, 1, p. 1-17 17 p., 140.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Drug accumulation in the presence of the multidrug resistance pump: dissociation between verapamil accumulation and the action of P-glycoprotein

      Ayesh, S., Litman, Thomas & Stein, W. D., 1997, In: Receptors and Channels. 5, 3-4, p. 175-83 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. E-pub ahead of print

      Effect of anterior quadratus lumborum block with ropivacaine on the immune response after laparoscopic surgery in colon cancer: a substudy of a randomized clinical trial

      Balsevicius, L., Urbano, P. C. M., Hasselager, R. P., Mohamud, A. A., Olausson, M., Svraka, M., Wahlstrøm, K. L., Oppermann, C., Gögenur, D. S., Hølmich, E. R., Cappelen, B., Sækmose, S. G., Tanggaard, K., Litman, Thomas, Børglum, Jens, Brix, S. & Gögenur, Ismail, 2024, (E-pub ahead of print) In: Regional Anesthesia and Pain Medicine. 10 p., 104896.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      A simplified bacterial community found within the epidermis than at the epidermal surface of atopic dermatitis patients and healthy controls

      Barnes, Christopher James, Asplund, M., Clausen, M., Rasmussen, Linett, Olesen, C. M., Yüksel, Y. T., Andersen, P. S., Litman, Thomas, Holmstrøm, K., Bay, Lene, Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Agner, Tove & Hansen, Anders Johannes, 2023, In: BMC Microbiology. 23, 12 p., 273.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Temporal and Spatial Variation of the Skin-Associated Bacteria from Healthy Participants and Atopic Dermatitis Patients

      Barnes, Christopher James, Clausen, M., Asplund, M., Rasmussen, Linett, Olesen, C. M., Yüsel, Y. T., Andersen, P. S., Litman, Thomas, Hansen, Anders Johannes & Agner, Tove, 2022, In: mSphere. 7, 1, 14 p., e00917-21.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      The role of half-transporters in multidrug resistance

      Bates, S. E., Robey, R., Miyake, K., Rao, K., Ross, D. D. & Litman, Thomas, Dec 2001, In: Journal of Bioenergetics and Biomembranes. 33, 6, p. 503-11 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      The role of half-transporters in multidrug resistance

      Bates, S. E., Robey, R., Miyake, K., Rao, K., Ross, D. D. & Litman, Thomas, 2001, In: J Bioenerg Biomembr. 503-511, p. 33

      Research output: Contribution to journal › Journal article › Research

    12. Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data

      Bates, S. E., Eisch, R., Ling, A., Rosing, D., Turner, M., Pittaluga, S., Prince, H. M., Kirschbaum, M. H., Allen, S. L., Zain, J., Geskin, L. J., Joske, D., Popplewell, L., Cowen, E. W., Jaffe, E. S., Nichols, J., Kennedy, S., Steinberg, S. M., Liewehr, D. J., Showe, L. C. & 5 others, Steakley, C., Wright, J., Fojo, T., Litman, Thomas & Piekarz, R. L., Jul 2015, In: British Journal of Haematology. 170, 1, p. 96-109 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      New ABC transporters in multi-drug resistance

      Bates, S. E., Robey, R., Knutsen, T., Honjo, Y., Litman, Thomas & Dean, M., 1 Oct 2000, In: Expert Opinion On Therapeutic Targets. 4, 5, p. 561-580 20 p.

      Research output: Contribution to journal › Review › Research › peer-review

    14. Published

      IκBζ is a key player in the antipsoriatic effects of secukinumab

      Bertelsen, T., Ljungberg, C., Litman, Thomas, Huppertz, C., Hennze, R., Rønholt, K., Iversen, L. & Johansen, C., 2020, In: Journal of Allergy and Clinical Immunology. 145, 1, p. 379-390 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

      Brangi, M., Litman, Thomas, Ciotti, M., Nishiyama, K., Kohlhagen, G., Takimoto, C., Robey, R., Pommier, Y., Fojo, T. & Bates, S. E., 1 Dec 1999, In: Cancer Research. 59, 23, p. 5938-46 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      HSP90 inhibitor RGRN‐305 for oral treatment of plaque‐type psoriasis: efficacy, safety and biomarker results in an open‐label proof‐of‐concept study

      Bregnhøj, A., Thuesen, K. K. H., Emmanuel, T., Litman, Thomas, Grek, C. L., Ghatnekar, G. S., Johansen, C. & Iversen, L., 2022, In: British Journal of Dermatology. 186, 5, p. 861-874

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Colonic Stent as Bridge to Surgery for Malignant Obstruction Induces Gene Expressional Changes Associated with a More Aggressive Tumor Phenotype

      Broholm, M., Degett, T. H., Furbo, S., Fiehn, Anne-Marie Kanstrup, Bulut, Mustafa, Litman, Thomas, Eriksen, J. O., Troelsen, J. T., Gjerdrum, Lise Mette Rahbek & Gögenur, Ismail, 2021, In: Annals of Surgical Oncology. 28, S3, p. 481–482

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    18. Published

      Single-cell heterogeneity in Sézary syndrome.

      Buus, Terkild Brink, Willerslev-Olsen, A., Fredholm, S. M., Blümel, E., Nastasi, C., Gluud, Maria, Hu, T., Lindahl, L. M., Iversen, L., Fogh, H., Gniadecki, R., Litvinov, I. V., Persson, J. L., Bonefeld, Charlotte Menne, Geisler, Carsten, Christensen, Jan Pravsgaard, Krejsgaard, T. F., Litman, Thomas, Woetmann, Anders & Ødum, Niels, 2018, In: Blood advances. 2, 16, p. 2115-2126

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      C10orf99/GPR15L Regulates Proinflammatory Response of Keratinocytes and Barrier Formation of the Skin

      Dainichi, T., Nakano, Y., Doi, H., Nakamizo, S., Nakajima, S., Matsumoto, R., Farkas, T., Wong, P. M., Narang, V., Moreno Traspas, R., Kawakami, E., Guttman-Yassky, E., Dreesen, O., Litman, Thomas, Reversade, B. & Kabashima, K., 2022, In: Frontiers in Immunology. 13, 825032.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells

      Dejligbjerg, M., Grauslund, M., Litman, Thomas, Collins, L., Qian, X., Jeffers, M., Lichenstein, H., Jensen, P. B. & Sehested, M., 12 Sep 2008, In: Molecular Cancer. 7, 70.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Human pathways in animal models: possibilities and limitations

      Doncheva, Nadezhda Tsankova, Palasca, Oana, Yarani, R., Litman, Thomas, Anthon, Christian, Groenen, M. A. M., Stadler, P. F., Pociot, Flemming, Jensen, Lars Juhl & Gorodkin, Jan, 2021, In: Nucleic Acids Research. 49, 4, p. 1859-1871 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Molecular cloning of a K+ channel from the malaria parasite Plasmodium falciparum

      Ellekvist, P., Ricke, C. H., Litman, Thomas, Salanti, Ali, Colding, H., Zeuthen, Thomas & Klærke, Dan Arne, 2004, In: Biochemical and Biophysical Research Communications. 318, 2, p. 477-84 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Tumor-Preferential Induction of Immune Responses and Epidermal Cell Death in Actinic Keratoses by Ingenol Mebutate

      Emmert, S., Haenssle, H. A., Zibert, J. R., Schön, M., Hald, A., Hansen, M. H., Litman, Thomas & Schön, M. P., 2016, In: PLOS ONE. 11, 9, p. e0160096

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection

      Esaki, H., Ewald, D. A., Ungar, B., Rozenblit, M., Zheng, X., Xu, H., Estrada, Y. D., Peng, X., Mitsui, H., Litman, Thomas, Suárez-Fariñas, M., Krueger, J. G. & Guttman-Yassky, E., Jan 2015, In: The Journal of allergy and clinical immunology. 135, 1, p. 153-63 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways

      Ewald, D. A., Malajian, D., Krueger, J. G., Workman, C. T., Wang, T., Tian, S., Litman, Thomas, Guttman-Yassky, E. & Suárez-Fariñas, M., 12 Oct 2015, In: BMC Medical Genomics. 8, p. 60

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling

      Ewald, D. A., Noda, S., Oliva, M., Litman, Thomas, Nakajima, S., Li, X., Xu, H., Workman, C. T., Scheipers, P., Svitacheva, N., Labuda, T., Krueger, J. G., Suárez-Fariñas, M., Kabashima, K. & Guttman-Yassky, E., 2017, In: Journal of Allergy and Clinical Immunology. 139, 2, p. 562-571 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues

      Fetsch, P. A., Abati, A., Litman, Thomas, Morisaki, K., Honjo, Y., Mittal, K. & Bates, S. E., 2006, In: Cancer Letters. 235, 1, p. 84-92 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Metastatic and recurrent adrenocortical cancer is not defined by its genomic landscape

      Fojo, T., Huff, L., Litman, Thomas, Im, K., Edgerly, M., del Rivero, J., Pittaluga, S., Merino, M., Bates, S. E. & Dean, M., 2020, In: BMC Medical Genomics. 13, 15 p., 165.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      The rectal cancer microRNAome - microRNA expression in rectal cancer and matched normal mucosa

      Gaedcke, J., Grade, M., Camps, J., Søkilde, R., Kaczkowski, B., Schetter, A. J., Difilippantonio, M. J., Harris, C. C., Ghadimi, B. M., Møller, S., Beissbarth, T., Ried, T. & Litman, Thomas, 2012, In: Clinical Cancer Research. 18, 18, p. 4919-4930 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      MicroRNAs in the pathogenesis, diagnosis, prognosis and targeted treatment of cutaneous T-cell lymphomas

      Gluud, Maria, Willerslev-Olsen, A., Gjerdrum, Lise Mette Rahbek, Lindahl, L. M., Buus, Terkild Brink, Andersen, Mads Hald, Bonefeld, Charlotte Menne, Krejsgaard, T., Litvinov, I. V., Iversen, L., Becker, J. C., Persson, J. L., Koralov, S. B., Litman, Thomas, Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 2020, In: Cancers. 12, 5, 18 p., 1229.

      Research output: Contribution to journal › Review › Research › peer-review

    31. Published

      MicroRNA-93 Targets p21 and Promotes Proliferation in Mycosis Fungoides T Cells

      Gluud, Maria, Fredholm, S., Blümel, E., Willerslev-Olsen, A., Buus, Terkild Brink, Nastasi, C., Krejsgaard, T., Bonefeld, Charlotte Menne, Woetmann, Anders , Iversen, L., Litman, Thomas, Geisler, Carsten, Ødum, Niels & Lindahl, L. M., 2021, In: Dermatology. 237, p. 277–282

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Malignant T cells induce skin barrier defects through cytokine-mediated JAK/STAT signaling in cutaneous T-cell lymphoma

      Gluud, M., Pallesen, E. M. H., Buus, T. B., Gjerdrum, L. M. R., Lindahl, L. M., Kamstrup, M. R., Bzorek, M., Danielsen, M., Bech, R., Monteiro, M. N., Blümel, E., Willerslev-Olsen, A., Lykkebo-Valløe, A., Vadivel, C. K., Krejsgaard, T., Bonefeld, C. M., Geisler, C., Becker, J. C., Koralov, S. B., Iversen, L. & 3 others, Litman, Thomas, Woetmann, Anders & Ødum, Niels, 2023, In: Blood. 141, 2, p. 180-193 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503

      Gorbatenko, A., Søkilde, R., Sorensen, E. E., Newie, I., Persson, H., Morancho, B., Arribas, J., Litman, Thomas, Rovira, C. & Pedersen, Stine Helene Falsig, 2019, In: Scientific Reports. 9, 1, p. 1-16 3352.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer

      Gravgaard, K. H., Lyng, M. B., Laenkholm, A., Søkilde, R., Nielsen, B. S., Litman, Thomas & Ditzel, H., 2012, In: Breast Cancer Research and Treatment. 134, 1, p. 207-217 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Measurement of cell volume changes by fluorescence self-quenching

      Hamann, Steffen, Kiilgaard, J. F., Litman, Thomas, Alvarez-Leefmans, F. J., Winther, B. R. & Zeuthen, Thomas, 2002, In: Journal of Fluorescence. 12, 2, p. 139-145 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      IFN-α primes T- and NK-cells for IL-15-mediated signaling and cytotoxicity

      Hansen, M. L., Woetmann, Anders , Krejsgaard, T., Kopp, K. L. M., Søkilde, R., Litman, Thomas, Straten, P. T., Geisler, Carsten, Wasik, M. A., Ødum, Niels & Eriksen, K. W., Sep 2011, In: Molecular Immunology. 48, 15-16, p. 2087-93 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2

      Henriksen, U. B., Fog, J. U., Litman, Thomas & Gether, Ulrik, 4 Nov 2005, In: Journal of Biological Chemistry. 280, 44, p. 36926-34 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2

      Henriksen, U. B., Gether, Ulrik & Litman, Thomas, 1 Apr 2005, In: Journal of Cell Science. 118, Pt 7, p. 1417-26 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells

      Honjo, Y., Hrycyna, C. A., Yan, Q. W., Medina-Pérez, W. Y., Robey, R. W., van de Laar, A., Litman, Thomas, Dean, M. & Bates, S. E., 15 Sep 2001, In: Cancer Research. 61, 18, p. 6635-6639 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome

      Hu, T., Buus, T. B., Krejsgaard, T., Nansen, A., Lundholt, B. K., Spee, P., Fredholm, S., Petersen, D. L., Blümel, E., Gluud, M., Monteiro, M. N., Willerslev-Olsen, A., Andersen, M. H., Straten, P. T., Met, Ö., Stolearenco, V., Fogh, H., Gniadecki, R., Nastasi, C., Litman, T. & 3 others, Woetmann, Anders , Gjerdrum, Lise Mette Rahbek & Ødum, Niels, 2019, In: OncoTarget. 10, 47, p. 4894-4906 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Profiling the Atopic Dermatitis Epidermal Transcriptome by Tape Stripping and BRB-seq

      Hu, T., Todberg, T., Andersen, D., Danneskiold-Samsøe, Niels Banhos, Hansen, Sofie Boesgaard Neestrup, Kristiansen, Karsten, Ewald, D. A., Brix, S., da Rosa, J. C., Hoof, I., Skov, Lone & Litman, Thomas, 2022, In: International Journal of Molecular Sciences. 23, 11, 12 p., 6140.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Assessment of Spatial and Temporal Variation in the Skin Transcriptome of Atopic Dermatitis by Use of 1.5 mm Minipunch Biopsies

      Hu, T., Todberg, T., Ewald, D. A., Hoof, I., Correa da Rosa, J., Skov, Lone & Litman, Thomas, 2023, In: Journal of Investigative Dermatology. 143, 4, p. 612-620.e6

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      MicroRNA expression profiles associated with development of drug resistance in Ehrlich ascites tumor cells

      Husted, S., Søkilde, R., Rask, L., Cirera, S., Busk, P. K., Eriksen, J. & Litman, Thomas, 5 Dec 2011, In: Molecular Pharmaceutics. 8, 6, p. 2055-62 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Gene expression profiling in chemoresistant variants of three cell lines of different origin

      Johnsson, A., Vallon-Christensson, J., Strand, C., Litman, Thomas & Eriksen, J., 2005, In: Anticancer Research. 25, 4, p. 2661-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma

      Kopp, K. L., Ralfkiaer, U., Gjerdrum, Lise Mette Rahbek, Helvad, R., Pedersen, I. H., Litman, Thomas, Jønson, L., Hagedorn, P. H., Krejsgaard, T., Gniadecki, R., Bonefeld, Charlotte Menne, Skov, Lone, Geisler, Carsten, Wasik, M. A., Ralfkiaer, E., Ødum, Niels & Woetmann, A., 2013, In: Cell Cycle. 12, 12, p. 1939-47 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      MicroRNA-106b Regulates Expression of the Tumour Suppressors p21 and TXNIP and Promotes Tumour Cell Proliferation in Mycosis Fungoides

      Lindahl, L. M., Gluud, Maria, Emmanuel, T., Thomsen, E. A., Hu, T., Rittig, A. H., Celis, P., Stolearenco, V., Krejsgaard, T., Johansen, C., Willerslev-Olsen, A., Buus, Terkild Brink, Woetmann, Anders , Aagaard, L., Geisler, Carsten, Litman, Thomas, Mikkelsen, J. G., Ødum, Niels & Iversen, L., 2020, In: Acta Dermato-Venereologica. 100, 8 p., adv00270.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Antibiotics inhibit tumor and disease activity in cutaneous T cell lymphoma

      Lindahl, L. M., Willerslev-Olsen, A., Gjerdrum, L. M. R., Nielsen, P. R., Blümel, E., Rittig, A. H., Celis, P., Herpers, B., Becker, J. C., Stausbøl-Grøn, B., Wasik, M. A., Gluud, M., Fredholm, S., Buus, T. B., Johansen, C., Nastasi, C., Peiffer, L., Kubat, L., Bzorek, M., Eriksen, J. O. & 11 others, Krejsgaard, T., Bonefeld, Charlotte Menne, Geisler, Carsten, Mustelin, T., Langhoff, E., Givskov, Michael, Woetmann, Anders , Kilian, M., Litman, Thomas, Iversen, L. & Ødum, Niels, 26 Sep 2019, In: Blood. 134, 13, p. 1072-1083

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Prognostic miRNA classifier in early-stage mycosis fungoides: development and validation in a Danish nationwide study

      Lindahl, L. M., Besenbacher, S., Rittig, A. H., Celis, P., Willerslev-Olsen, A., Gjerdrum, Lise Mette Rahbek, Krejsgaard, T., Johansen, C., Litman, Thomas, Woetmann, Anders , Ødum, Niels & Iversen, L., 2018, In: Blood. 131, 7, p. 759-770 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Personalized medicine - concepts, technologies, and applications in inflammatory skin diseases

      Litman, Thomas, 2019, In: APMIS - Journal of Pathology, Microbiology and Immunology. 127, 5, p. 386-424 39 p.

      Research output: Contribution to journal › Review › Research › peer-review

    50. Published

      Ancient lineages of the keratin-associated protein (KRTAP) genes and their co-option in the evolution of the hair follicle

      Litman, Thomas & Stein, W. D., 2023, In: BMC Ecology and Evolution. 23, 7.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity

      Litman, Thomas, Zeuthen, Thomas, Skovsgaard, T. & Stein, W. D., 1997, In: BBA General Subjects. vol. 1361, p. 169-176

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2

      Litman, Thomas, Jensen, U., Hansen, Alastair, Covitz, K., Zhan, Z., Fetsch, P., Abati, A., Hansen, Paul Robert, Horn, T., Skovsgaard, T. & Bates, S. E., 20 Sep 2002, In: BBA General Subjects. 1565, 1, p. 6-16 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Pumping of drugs by P-glycoprotein: a two-step process?

      Litman, Thomas, Skovsgaard, T. & Stein, W. D., 2003, In: Pharmacol Exp Ther.. 307(3), p. 846-853

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Lipid composition of sensitive and multidrug resistant Ehrlich ascites tumour cells

      Litman, Thomas, Nielsen, D., Skovsgaard, T. & Bukhave, K., 1995, In: Cellular Pharmacology. Vol 2, p. 9-14

      Research output: Contribution to journal › Journal article › Research

    55. Published

      From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance

      Litman, Thomas, Druley, T. E., Stein, W. D. & Bates, S. E., 2001, In: Cell Mol Life Sci.. 931-959, p. 58

      Research output: Contribution to journal › Journal article › Research

    56. Published

      From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance

      Litman, Thomas, Druley, T. E., Stein, W. D. & Bates, S. E., Jun 2001, In: Cellular and molecular life sciences : CMLS. 58, 7, p. 931-59 29 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Ammonia and urea permeability of mammalian aquaporins

      Litman, Thomas, Søgaard, R. & Zeuthen, Thomas, 2009, In: Handbook of Experimental Pharmacology. 190, p. 327-58 31 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Published

      Obtaining estimates for the ages of all the protein-coding genes and most of the ontology-identified noncoding genes of the human genome, assigned to 19 phylostrata

      Litman, Thomas & Stein, W. D., 2019, In: Seminars in Oncology. 46, 1, p. 3-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Structure-activity relationships of P-glycoprotein interacting drugs: kinetic characterization of their effects on ATPase activity

      Litman, Thomas, Zeuthen, Thomas, Skovsgaard, T. & Stein, W. D., 1997, In: BBA General Subjects. 1361, 2, p. 159-168

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells

      Litman, Thomas, Pedersen, S. F., Kramhøft, B., Skovsgaard, T. & Hoffmann, E. K., 1998, In: Cellular Physiology and Biochemistry. 8, 3, p. 138-50 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Pumping of drugs by P-glycoprotein: a two-step process?

      Litman, Thomas, Skovsgaard, T. & Stein, W. D., Dec 2003, In: Journal of Pharmacology and Experimental Therapeutics. 307, 3, p. 846-53 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells

      Litman, Thomas, Pedersen, Stine Helene Falsig, Kramhøft, B., Skovsgaard, T. & Hoffmann, E. K., 1998, In: Cell. Physiol. Biochem.. 8, p. 138-150

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      ATPase activity of P-glycoprotein related to emergence of drug resistance in Ehrlich ascites tumor cell lines

      Litman, Thomas, Nielsen, D., Skovsgaard, T., Zeuthen, Thomas & Stein, W. D., 1997, In: BBA General Subjects. 1361, 2, p. 147-158

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. Published

      The multidrug resistant phenotype - A comparative study

      Litman, Thomas, 1 Dec 1997, In: Ugeskrift for Laeger. 159, 6, p. 771-772 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. Published

      The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

      Litman, Thomas, Brangi, M., Hudson, E., Fetsch, P., Abati, A., Ross, D. D., Miyake, K., Resau, J. H. & Bates, S. E., Jun 2000, In: Journal of Cell Science. 113 ( Pt 11), p. 2011-21 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. Published

      Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

      Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 5 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 3, p. 1683-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    67. Histone deacetylase inhibitor-mediated cell death is distinct from its global effect on chromatin

      Luchenko, V. L., Litman, Thomas, Chakraborty, A. R., Heffner, A., Devor, C., Wilkerson, J., Stein, W., Robey, R. W., Bangiolo, L., Levens, D. & Bates, S. E., 2014, In: Molecular Oncology. 8, 8, p. 1379-1392 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Global microRNA expression profiling of high-risk ER+ breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG study

      Lyng, M. B., Lænkholm, A. V., Søkilde, R., Gravgaard, K. H., Litman, Thomas & Ditzel, H., 2012, In: PloS one. 7, 5, p. e36170

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. Published

      Generation of an activating ZN(2+) switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

      Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 2002, In: Proceedings of the National Academy of Science of the United States of America. vol. 99(3), p. 1683-8

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      Gene expression analysis during progression of malignant meningioma compared to benign meningioma

      Maier, A. D., Meddis, Alessandra, Mirian, C., Haslund-Vinding, Jeppe Lohfert, Bartek, J., Krog, S. M., Nguyen, T. U. P., Areškevičiūtė, A., Melchior, L. C., Heegaard, Steffen, Kristensen, Bjarne Winther, Munch, Tina Nørgaard, Fugleholm, Kåre, Ziebell, M., Raleigh, D. R., Poulsen, F. R., Gerds, Thomas Alexander, Litman, Thomas, Scheie, David & Mathiesen, Tiit Illimar, 2023, In: Journal of Neurosurgery. 138, 5, p. 1-11 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Published

      Validation of a diagnostic miRNA classifier in cutaneous T-cell lymphomas

      Marstrand, T., Ahler, C. B., Ralfkiaer, U., Clemmensen, A., Kopp, K. L., Sibbesen, N. A., Krejsgaard, T., Litman, Thomas, Wasik, M. A., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Gjerdum, L. M. R., Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Woetmann, Anders , Røpke, M. A., Glue, C., Skov, Lone & Ødum, Niels, 2014, In: Leukemia and Lymphoma. 55, 4, p. 957-958 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. Published

      Distinct molecular signatures of mild extrinsic and intrinsic atopic dermatitis

      Martel, B. C., Litman, Thomas, Hald, A., Norsgaard, H., Lovato, P., Dyring-Andersen, Beatrice, Skov, Lone, Thestrup-Pedersen, K., Skov, Søren, Skak, K. & Poulsen, Lars K., Jun 2016, In: Experimental Dermatology Online. 25, 6, p. 453-459 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    73. Published

      Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer

      Martens-Uzunova, E. S., Jalava, S. E., Dits, N. F., van Leenders, G. J. L. H., Møller, S., Trapman, J., Bangma, C. H., Litman, Thomas, Visakorpi, T. & Jenster, G., 18 Jul 2011, In: Oncogene. 31, 8, p. 978-991 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    74. Published

      Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

      Miyake, K., Mickley, L., Litman, Thomas, Zhan, Z., Robey, R., Cristensen, B., Brangi, M., Greenberger, L., Dean, M., Fojo, T. & Bates, S. E., 1 Jan 1999, In: Cancer Research. 59, 1, p. 8-13 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. Published

      Repeated monthly epicutaneous challenges with diphenylcyclopropenone result in a clinically reproducible level of contact allergy in de novo sensitized individuals

      Mose, K. F., Andersen, F., Skov, Lone, Røpke, M. A., Litman, Thomas, Friedmann, P. S. & Andersen, K. E., Apr 2017, In: British Journal of Dermatology. 176, 4, p. 1095-1097

      Research output: Contribution to journal › Letter › Research › peer-review

    76. Published

      The gene expression and immunohistochemical time-course of diphenylcyclopropenone-induced contact allergy in healthy humans following repeated epicutaneous challenges

      Mose, K. F., Burton, M., Thomassen, M., Andersen, F., Kruse, T. A., Tan, Q., Skov, Lone, Ropke, M. A., Litman, Thomas, Clemmensen, O., Kristensen, B. W., Friedmann, P. S. & Andersen, K. E., Oct 2017, In: Experimental Dermatology. 26, 10, p. 926-933

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Elevated NK-cell transcriptional signature and dysbalance of resting and activated NK cells in atopic dermatitis

      Möbus, L. & TREATgermany Study Group, T. S. G., 2021, In: Journal of Allergy and Clinical Immunology. 147, 5, p. 1959-1965.e2

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      LAG3 and TIGIT Expression on Tumor-Infiltrating Lymphocytes in Cutaneous Melanoma

      Naimy, S., Bzorek, M., Eriksen, J. O., Løvendorf, Marianne Bengtson, Litman, Thomas, Dyring-Andersen, Beatrice & Gjerdrum, Lise Mette Rahbek, 2024, In: Dermatology. 240, p. 156-163

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. E-pub ahead of print

      Comparative quantitative proteomic analysis of melanoma subtypes, nevus-associated melanoma, and corresponding nevi

      Naimy, S., Sølberg, J. B. K., Kuczek, D. E., Løvendorf, Marianne Bengtson, Bzorek, M., Litman, Thomas, Mund, Andreas, Gjerdrum, Lise Mette Rahbek, Clark, R. A., Mann, Matthias & Dyring-Andersen, Beatrice, 5 Jan 2024, (E-pub ahead of print) In: The Journal of Investigative Dermatology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. Published

      Inhibition of succinate dehydrogenase activity impairs human T cell activation and function: [Publisher correction]

      Nastasi, C., Willerlev-Olsen, A., Dalhoff, K., Ford, Shayne Lavondua, Gadsbøll, A. S. Ø., Buus, Terkild Brink, Gluud, Maria, Danielsen, M., Litman, Thomas, Bonefeld, Charlotte Menne, Geisler, Carsten, Ødum, Niels & Woetmann, Anders , 2021, In: Scientific Reports. 11, 1, 1458.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Published

      Structural determinants underlying permeant discrimination of the Cx43 hemichannel

      Nielsen, B. S., Zonta, F., Farkas, T., Litman, Thomas, Nielsen, Morten Schak & MacAulay, Nanna, 2019, In: Journal of Biological Chemistry. 294, 45, p. 16789-16803 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. Published

      Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone

      Nielsen, D., Eriksen, J., Maare, C., Litman, Thomas, Kjaersgaard, E., Plesner, T., Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 363-70 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Published

      Expression of P-glycoprotein and multidrug resistance associated protein in Ehrlich ascites tumor cells after fractionated irradiation

      Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas & Skovsgaard, T., 15 Nov 2001, In: International Journal of Radiation Oncology, Biology, Physics. 51, 4, p. 1050-7 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. Published

      Characterisation of multidrug-resistant Ehrlich ascites tumour cells selected in vivo for resistance to etoposide

      Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas, Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 353-61 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    85. Published

      Expression of P-glycoprotein and multidrug resistance associated protein in Ehrlich ascites tumor cells after fractionated irradiation

      Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas & Skovsgaard, T., 2001, In: Int J Radiat Oncol Biol Phys. 51, p. 1050-1057

      Research output: Contribution to journal › Journal article › Research

    86. Published

      Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone

      Nielsen, D., Eriksen, J., Maare, C., Litman, Thomas, Kjaersgaard, E., Plesner, T., Friche, E. & Skovsgaard, T., 2000, In: Biochem Pharmacol.. 363-370, p. 60

      Research output: Contribution to journal › Journal article › Research

    87. Published

      Diagnostic Two-Gene Classifier in Early-Stage Mycosis Fungoides: A Retrospective Multicenter Study

      Nielsen, Pia Rude, Eriksen, J. O., Lindahl, L. M., Wehkamp, U., Bzorek, M., Andersen, G., Woetmann, Anders , Iversen, L., Ødum, Niels, Litman, Thomas & Gjerdrum, Lise Mette Rahbek, 2021, In: Journal of Investigative Dermatology. 141, 1, p. 213-217.e5

      Research output: Contribution to journal › Letter › Research › peer-review

    88. Published

      Role of B-cells in mycosis fungoides

      Nielsen, Pia Rude, Eriksen, J. O., Sørensen, M. D., Wehkamp, U., Lindahl, L. M., Bzorek, M., Iversen, L., Woetmann, Anders , Ødum, Niels, Litman, Thomas & Gjerdrum, Lise Mette Rahbek, 2021, In: Acta Dermato-Venereologica. 101, 3, adv00413.

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. The molecular signature of chronic prurigo

      Ohanyan, T., Litman, Thomas, Hawro, T., Schoepke, N., Koopmann, W., Maurer, M. & Metz, M., 2018, In: Experimental Dermatology. 27, 3, p. E79-E79 P180.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    90. Published

      Altered Maturation of the Skin Microbiome in Infants with Atopic Dermatitis

      Olesen, C. M., Clausen, M. L., Agner, Tove, Asplund, M., Rasmussen, Linett, Yüksel, Y. T., Andersen, P. S., Litman, Thomas, Hansen, Anders Johannes & Barnes, Christopher James, 2022, In: Acta Dermato-Venereologica. 102, 7 p., adv00817.

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. Published

      Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

      Ozvegy, C., Litman, Thomas, Szakács, G., Nagy, Z., Bates, S., Váradi, A. & Sarkadi, B., 6 Jul 2001, In: Biochemical and Biophysical Research Communications. 285, 1, p. 111-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

      Ozvegy, C., Litman, Thomas, Szakacs, G., Nagy, Z., Bates, S., Varadi, A. & Sarkadi, B., 2001, In: Biochem. Biophys. Res. Commun.. 285, p. 111-117

      Research output: Contribution to journal › Journal article › Research

    93. Published

      Adrenocortical cancer: A molecularly complex disease where surgery matters

      Payabyab, E. C., Balasubramaniam, S., Edgerly, M., Velarde, M., Merino, M. J., Venkatesan, A. M., Leuva, H., Litman, Thomas, Bates, S. E. & Fojo, T., 15 Oct 2016, In: Clinical Cancer Research. 22, 20, p. 4989-5000 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      Ablative fractional laser treatment reduces hedgehog pathway gene expression in murine basal cell carcinomas

      Pedersen, K. K., Granborg, J. R., Lerche, Catharina Margrethe, Litman, Thomas, Olesen, U. H. & Hædersdal, Merete, 2024, In: Lasers in Medical Science. 39, 1, 9 p., 55.

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Published

      Topical Delivery of Hedgehog Inhibitors: Current Status and Perspectives

      Pedersen, K. K., Høyer-Hansen, M. H., Litman, Thomas, Hædersdal, Merete & Olesen, U. H., 2022, In: International Journal of Molecular Sciences. 23, 22, 14191.

      Research output: Contribution to journal › Review › Research › peer-review

    96. Published

      How the RNA isolation method can affect microRNA microarray results

      Podolska, A., Kaczkowski, B., Litman, Thomas, Fredholm, Merete & Cirera, Susanna, 2011, In: Acta Biochimica Polonica. 58, 4, p. 535-540 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. Published

      Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells

      Poulsen, K. A., Litman, Thomas, Eriksen, J., Mollerup, J. & Lambert, Ian Henry, Jun 2002, In: Amino Acids. 22, 4, p. 333-50 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    98. Published

      Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells

      Poulsen, K. A., Litman, Thomas, Eriksen, J., Mollerup, J. & Lambert, Ian Henry, 2002, In: Amino Acids. 22, p. 333-350

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Published

      Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)

      Ralfkiaer, U., Hagedorn, P., Bangsgaard, N., Løvendorf, M. B., Ahler, C. B., Svensson, L., Kopp, K. L., Vennegaard, M. T., Lauenborg, B., Zibert, J. R., Krejsgaard, T., Bonefeld, C. M., Søkilde, R., Gjerdrum, L. M., Labuda, T., Mathiesen, A-M., Grønbaek, K., Wasik, M. A., Sokolowska-Wojdylo, M., Queille-Roussel, C. & 9 others, Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Litman, Thomas, Woetmann, Anders , Glue, C., Røpke, M. A., Skov, Lone & Ødum, Niels, 2011, In: Blood. 118, 22, p. 5891-5900 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Published

      MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma

      Ralfkiaer, U., Lindahl, L. M., Litman, Thomas, Gjerdrum, Lise Mette Rahbek, Ahler, C. B., Gniadecki, R., Marstrand, T., Fredholm, S., Iversen, L., Wasik, M. A., Bonefeld, Charlotte Menne, Geisler, Carsten, Krejsgaard, T., Glue, C., Røpke, M. A., Woetmann, A., Skov, Lone, Grønbæk, Kirsten & Ødum, Niels, Dec 2014, In: Anticancer Research. 34, 12, p. 7207-17 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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