Thomas Mandel Clausen

Thomas Mandel Clausen

Associate Professor

  • CMP

    Blegdamsvej 3B

    2200 København N.

    Phone: +45 35 32 66 53

Member of:

  • VAR2CSA team


  1. 2012
  2. Published

    Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria

    Clausen, Thomas Mandel, Christoffersen, S., Dahlbäck, M., Langkilde, Annette Eva, Jensen, K. E., Resende, M., Agerbæk, Mette Ørskov, Andersen, D., Berisha, B., Ditlev, S. B., Pinto, V. V., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Larsen, Sine & Salanti, Ali, 2012, In : Journal of Biological Chemistry. 287, 28, p. 23332-45 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2014
  4. Published

    Characterization of human placental glycosaminoglycans and regional binding to VAR2CSA in malaria infected erythrocytes

    Beaudet, J. M., Mansur, L., Joo, E. J., Kamhi, E., Yang, B., Clausen, Thomas Mandel, Salanti, Ali, Zhang, F. & Linhardt, R. J., Feb 2014, In : Glycoconjugate Journal. 31, 2, p. 109-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2015
  6. Published

    Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein

    Salanti, Ali, Clausen, Thomas Mandel, Agerbæk, Mette Ørskov, Al Nakouzi, N., Dahlbäck, M., Oo, H. Z., Lee, S., Gustavsson, Tobias, Rich, J. R., Hedberg, B. J., Mao, Y., Barington, L., Pereira, M. A., LoBello, J., Endo, M., Fazli, L., Soden, J., Wang, C. K., Sander, A. F., Dagil, Robert, Thrane, Susan, Holst, Peter Johannes, Meng, L., Favero, F., Weiss, G. J., Nielsen, Morten Agertoug, Freeth, J., Nielsen, T. O., Zaia, J., Tran, N. L., Trent, J., Babcook, J. S., Theander, Thor Grundtvig, Sorensen, P. H. & Daugaard, M., 2015, In : Cancer Cell. 28, 4, p. 500-14 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2016
  8. Published

    Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting

    Clausen, Thomas Mandel, Ayres Pereira, M., Oo, H. Z., Resende, M., Gustavsson, Tobias, Mao, Y., Sugiura, N., Liew, J., Fazli, L., Theander, Thor Grundtvig, Daugaard, M. & Salanti, Ali, Jul 2016, In : Sensing and Bio-Sensing Research. 9, p. 23-30 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1

    Ayres Pereira, M., Clausen, Thomas Mandel, Pehrson, Caroline, Mao, Y., Resende, M., Daugaard, M., Riis Kristensen, A., Spliid, Charlotte Bredo, Mathiesen, Line, Knudsen, Lisbeth E., Damm, Peter, Theander, Thor Grundtvig, R Hansson, S., Nielsen, Morten Agertoug & Salanti, Ali, Aug 2016, In : P L o S Pathogens. 12, 8, 26 p., e1005831.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Molecular dissection of placental malaria protein VAR2CSA interaction with a chemo-enzymatically synthesized chondroitin sulfate library

    Sugiura, N., Clausen, Thomas Mandel, Shioiri, T., Gustavsson, Tobias, Watanabe, H. & Salanti, Ali, Dec 2016, In : Glycoconjugate Journal. 33, 6, p. 985-994 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Oncofetal chondroitin sulfate glycosaminoglycans are key players in integrin signaling and tumor cell motility

    Clausen, Thomas Mandel, Bento Ayres Pereira, M. M., Al Nakouzi, N., Oo, H. Z., Agerbæk, Mette Ørskov, Lee, S., Ørum-Madsen, M. S., Kristensen, A. R., El-Naggar, A., Grandgenett, P. M., Grem, J. L., Hollingsworth, M. A., Holst, Peter Johannes, Theander, Thor Grundtvig, Sorensen, P. H., Daugaard, M. & Salanti, Ali, Dec 2016, In : Molecular Cancer Research. 14, 12, p. 1288-1299 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2017
  13. Published

    An oncofetal glycosaminoglycan modification provides therapeutic access to Cisplatin-resistant bladder cancer

    Seiler, R., Oo, H. Z., Tortora, D., Clausen, Thomas Mandel, Wang, C. K., Kumar, G., Ayres Pereira, M., Ørum-Madsen, M. S., Agerbæk, Mette Ørskov, Gustavsson, Tobias, Nordmaj, Mie Anemone, Rich, J. R., Lallous, N., Fazli, L., Lee, S., Douglas, J., Todenhöfer, T., Esfandnia, S., Battsogt, D., Babcook, J. S., Al Nakouzi, N., Crabb, S. J., Moskalev, I., Kiss, B., Davicioni, E., Thalmann, G. N., Rennie, P. S., Black, P. C., Salanti, Ali & Daugaard, M., 2017, In : European Urology Supplements. 72, 1, p. 142-150 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration

    Agerbæk, Mette Ørskov, Bento Ayres Pereira, M. M., Clausen, Thomas Mandel, Pehrson, Caroline, Oo, H. Z., Spliid, Charlotte Bredo, Rich, J. R., Fung, V., Nkrumah, F., Neequaye, J., Biggar, R. J., Reynolds, S. J., Tosato, G., Pullarkat, S. T., Ayers, L. W., Theander, Thor Grundtvig, Daugaard, M., Bhatia, K., Nielsen, Morten Agertoug, Mbulaiteye, S. M. & Salanti, Ali, 2017, In : International Journal of Cancer. 140, 7, p. 1597–1608 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2018
  16. Published

    The GAGOme: a cell-based library of displayed glycosaminoglycans

    Chen, Y., Narimatsu, Yoshiki, Clausen, Thomas Mandel, Gomes, C., Karlsson, R., Steentoft, Catharina, Spliid, Charlotte Bredo, Gustavsson, Tobias, Salanti, Ali, Persson, A., Malmström, A., Willén, D., Ellervik, U., Bennett, Eric Paul, Mao, Y., Clausen, Henrik & Yang, Zhang, 2018, In : Nature Methods. 15, 11, p. 881-888

    Research output: Contribution to journalJournal articleResearchpeer-review

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