The T Cell Biology and Skin Inflammation Group
Our goal is to get a better understanding of how T cells are activated, differentiated and maintained in the skin and the role they play locally and systemically. We hope that this will lead to a better understanding of inflammatory skin diseases which could result in the development of better treatments.
We use in vitro models including cell lines and cells purified from healthy individuals, in vivo mouse models and patient samples from patients with inflammatory skin diseases. This setup allow us to take our research from the bench to the bedside and back again.
- We have found that Vitamin D plays a central role in activation of naïve T cells and in regulation of the T cell response.
- We have shown that mixtures of contact allergens enhances the response to single allergens within the mixture.
- We have shown that epidermal resident T cells plays a critical role in inducing a rapid response to contact allergens and that the composition of epidermal resident T cells is tightly regulated during the response to contact allergens.
T Cell Biology and Skin Inflammation
Department of Immunology and Microbiology
University of Copenhagen - Panum Institute
Blegdamsvej 3 - Maersk Tower 07.12.85
DK-2200 Copenhagen K
Professor Charlotte Menné Bonefeld
|Anne-Sofie Østergaard Gadsbøll||Postdoc||+4535336887|
|Charlotte Menne Bonefeld||Head of Department||+4535327866|
|Charlotte Menne Bonefeld||Professor||+4535327866|
|Fatima Abdul Hassan Al-Jaberi||PhD Student||+4535332373|
|Kelvin Yeung||PhD Student||+4535335824|
|Louise Mørk||Laboratory Technician||+4535336603|
|Martin Kongsbak-Wismann||Assistant Professor||+4535337401|
|Veronika Mraz||PhD Student||+4531322376|