19 October 2022

Bacteria control their metabolism when going into biofilm formation


This shift in metabolism has strong implications for tolerance to antibiotics


In a new paper out now in  Cell Reports, a research team from Costerton Biofilm Center at the Department of Immunology and Microbiology (ISIM), University of Copenhagen - with Assistant professor Mads Lichtenberg, Assistant professor Kasper Nørskov Kragh, Professor Tim Tolker-Nielsen and Professor Thomas Bjarnsholt in front - describes how in response to cyclic-di-GMP, bacterial populations exhibit a burst of metabolic activity followed by a prolonged period of low metabolic activity as they enter the biofilm state. 

This fundamental research using biocalorimetry helps us to better understand biofilm formation which can have big implications for human health.

This research team is well known for their high-impact work in the field of biofilm and chronic infections. You can contact them here:

Assistant professor Mads Lichtenberg

Assistant professor Kasper Nørskov Kragh

Professor Tim Tolker-Nielsen

Professor Thomas Bjarnsholt 

You can read more here in Cell Reports